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Articles tagged "Intestinal transplantation"

  • 2017 American Transplant Congress

    Renal Outcomes Following Intestinal Transplantation.

    C. Puttarajappa,1 A. Humar,1 S. Hariharan,1 R. Cruz Jr,1 A. Ganoza,1 D. Landsittel,1,3 X. Gao,3 M. Bhattarai,1 H. Sogawa.1,2

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; 2Abdominal Transplant & Hepatobiliary Surgery, New York Medical College/ Westchester Medical Center, Valhalla, NY; 3Section on Biomarkers and Prediction Modeling, University of Pittsburgh, Pittsburgh, PA

    Purpose: Single center study of Intestinal Transplant recipients to evaluate epidemiology of dialysis and renal transplantation(RT) following Intestinal transplantation(IT).Methods: 288 adult patients who underwent first…
  • 2017 American Transplant Congress

    Ex Vivo Normothermic Perfusion of Isolated Segmental Porcine Bowel: A Novel Functional Model of the Small Intestine.

    M. Hamed,1 A. Barlow,1 S. Khosla,1 A. Sagar,1 F. Gribble,2 M. Murphy,3 G. Pettigrew,1 E. Bolton,1 J. Bradley,1 M. Nicholson,1 S. Hosgood,1 K. Saeb-Parsy.1

    1University Department of Surgery, Cambridge NIHR Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, Cambridgeshire, United Kingdom; 2Wellcome Trust – MRC Institute of Metabolic Science, University of Cambridge, Cambridge, Cambridgeshire, United Kingdom; 3MRC Mitochondrial Biology Unit, Cambridge, Cambridgeshire, United Kingdom

    Introduction: There is a need for the development of suitable large animal models for research in gastroenterology and intestinal transplantation. Ex vivo normothermic perfusion (EVNP)…
  • 2017 American Transplant Congress

    Graft-versus-Host Disease in Intestine Transplantation.

    J. Clouse, C. Kubal, B. Ekser, J. Fridell, R. Mangus.

    Surgery, Indiana University School of Medicine, Indianapolis, IN

    PurposeThis study reports the incidence, location, and outcomes of graft-versus-host disease (GVHD) at an active intestine transplant center. Subgroup analysis is employed to assess for…
  • 2017 American Transplant Congress

    Effect of Preformed Donor-Specific Antibodies in Intestine/Multivisceral Transplantation.

    M. Safwan,1 M. Rizzari,1 K. Collins,1 A. Yoshida,1 S. Skorupski,2 O. Fagoaga,2 M. Abouljoud,1 S. Nagai.1

    1Divison of Transplant and Hepatobiliary Surgery, Henry Ford Transplant Institute, Detroit, MI; 2Transplant Immunology, Henry Ford Hospital, Detroit, MI

    Aim: To analyze the effect of preformed donor-specific antibodies (DSA) in intestine/multivisceral transplantation patients.Methods: Retrospective review of preformed and de novo DSAs of all intestine/multivisceral…
  • 2017 American Transplant Congress

    Intraabdominal Infections (IAI) and Bloodstream Infections in Small Intestinal and Multivisceral Transplants (IMVTX).

    A. Spence,1 S. Fogleman,1 G. Raffaele,2 C. Matsumoto,2 P. Kumar,1 R. Biswas,1 T. Fishbein,2 J. Timpone.1

    1Division of Infectious Diseases, Medstar Georgetown University Hospital, Washington, DC; 2Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington

    BackgroundIMVTX is a treatment option for patients with intestinal failure. IMVTX is often complicated by infection in the post-transplant period with the abdomen and bloodstream…
  • 2017 American Transplant Congress

    Evaluation of Cytomegalovirus Prophylaxis Regimens in Intestinal Transplant Recipients: A Single Center Experience.

    M. Eley,1 M. Keck,1 D. Collier,2 M. Vacha.1

    1Department of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, NE; 2College of Pharmacy: Department of Pharmacy Practice, University Of Nebraska Medical Center, Omaha, NE

    Purpose: To evaluate the incidence of cytomegalovirus (CMV) infection in intestinal transplant recipients after a change in an antiviral regimen.Methods: This was a retrospective review…
  • 2017 American Transplant Congress

    Donor Lymphoid Chimerism in Early Recognition and Prediction of Clinical Outcome Caused by Acute Graft versus Host Disease After Solid Organ Transplant.

    A. Zhang,1 Y. Sun,2 K. Hashimoto,4 M. Fujiki,4 M. Askar,3 J. Fung,5 C. Miller,4 K. Abu-Elmagd,4 B. Eghtesad.4

    1Cleveland Clinic, Allogen Laboratories, Cleveland, OH; 2Avalon University School of Medicine, Willemstad, Netherlands Antilles; 3Baylor University Medical Center, Dallas, TX; 4Transplantation Center, Cleveland Clinic, Cleveland, OH; 5Transplantation Center, University of Chicago, Chicago, IL

    Introduction: Acute graft versus host disease (aGvHD) after solid organ transplant (SOT) is rare but related with high mortality. Early accurate diagnosis is critical for…
  • 2017 American Transplant Congress

    Long-Term Outcomes of Renal Function in Pediatric Living Related Intestinal Transplantation.

    S. Garcia Aroz,1 K. Czech,2 L. Briar,2 G. Testa,3 E. Benedetti,1 E. John.2

    1Surgery, UIC, Chicago, IL; 2Pediatrics, UIC, Chicago, IL; 3Surgery, Baylor University, Texas

    Background: Renal function after organ transplantation is affected by several factors. The use of calcineurin inhibitors has a direct impact on the kidney. Material and…
  • 2017 American Transplant Congress

    Achieving Ideal Outcome After Intestinal Transplantation: How Close Are We?

    A. Ganoza,1 N. Celik,1 G. Bond,1 K. Soltys,1 J. Rudolph,2 R. Sindhi,1 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Intestinal Care and Rehabilitation Center, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Aim:To determine the incidence of factors affecting ideal outcome after pediatric intestinal transplantation (ITx).Methods: Children that underwent primary ITx with intact grafts at one year…
  • 2017 American Transplant Congress

    Impact of Donor Asystole in Intestine Transplant.

    J. Schroering, C. Kubal, R. Mangus.

    Surgery, Indiana University, Indianapolis, IN

    Intestine transplantation has a high risk of post-transplant complications. For this reason, many intestine transplant centers are conservative in their choice of deceased donors, using…
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