ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Intestinal transplantation"

  • 2019 American Transplant Congress

    Viral Enteritis in Intestinal Transplant Recipients

    A. Servais, M. Vacha, D. F. Florescu, M. Keck

    Nebraska Medicine, Omaha, NE

    *Purpose: To evaluate viral enteritis episodes in intestinal transplant recipients (ITR)*Methods: This retrospective review included ITR transplanted between January 2008 and December 2016. Data for…
  • 2019 American Transplant Congress

    The Role of the T Regulatory Cell Compartment in Intestinal Transplant Patients: Helpful or Unhinged?

    L. Belyayev1, M. Sadat2, K. Loh3, S. Moturi2, K. Khan2, J. Hawksworth2, C. Matsumoto2, T. M. Fishbein2, A. Kroemer2

    1Surgery, Walter Reed National Military Medical Center, Bethesda, MD, 2Transplant, MedStar Georgetown Transplant Institute, Washington D.C., DC, 3Pediatrics, Children’s National Medical Center, Washington D.C., DC

    *Purpose: The T regulatory (Treg) cell compartment has now been established as a key player in dampening T helper 17 (Th17) mediated inflammation, managing self-tolerance,…
  • 2019 American Transplant Congress

    Challenges to Inpatient Management Post Abdominal Wall Transplant (AWT) – From App’s Perspective

    K. Hattori, D. Sudan, K. Ravindra

    Duke University hospital, Durham, NC

    *Purpose: To highlight the unique features of caring for an AWT recipient and identify areas of improvement for future cases*Methods: AWT is an innovative adjunct…
  • 2019 American Transplant Congress

    An International Multicentre Validation Study of the Toronto Listing Criteria for Pediatric Intestinal Transplant

    A. J. Roberts1, P. W. Wales2, S. V. Beath3, H. M. Evans1, J. Hind4, T. Wong5, D. Mercer6, J. Yap7, C. Belza8, D. Grant9, Y. Avitzur10

    1Department of Paediatric Gastroenterology, Starship Child Health - Auckland District Health Board, Auckland, New Zealand, 2Division of General & Thoracic Surgery, Hospital for Sick Children, University of Toronto,, Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada, 3The Liver Unit, Birmingham Children’s Hospital, Birmingham, United Kingdom, 4Paediatric Liver, GI & Nutrition Centre, King's College Hospital, London, United Kingdom, 5The Liver Unit, Birmingham Children's Hospital, Birmingham, United Kingdom, 6Children’s Hospital and Medical Centre, Omaha, NE, 7Department of Pediatrics, University of Alberta, Edmonton, AB, Canada, 8Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada, 9Department of Surgery, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 10Division of Gastroenterology, Hepatology & Nutrition, Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada

    *Purpose: Current intestinal transplantation (IT) listing criteria from 2001 have limited ability to predict the need for IT in the current era of intestinal failure…
  • 2019 American Transplant Congress

    Surgical Management Of Five Hundred Patients With Chronic Gut Failure At A Single Center: Autologous Reconstruction Versus Transplantation

    S. Armanyous, Y. Fouda, M. Fujiki, N. Parekh, M. Osman, R. Girlanda, K. Hashimoto, G. Costa, K. Abu-Elmagd

    Cleveland Clinic, Cleveland, OH

    *Purpose: To define the evolving role of autologous gut reconstruction (AGR) in the management of total parenteral nutrition (TPN)-dependent-chronic gut failure (CGF) patients with special…
  • 2019 American Transplant Congress

    A National Survey of Immunosuppression Strategies in Intestinal Transplantation

    M. Segovia1, T. Beduschi2, J. Boike3, D. Farmer4, S. Horslen5, K. Iyer6, S. Jafri7, A. Langnas8, C. Matsumoto9, A. Mavis1, G. Mazariegos10, S. Nagai7, J. O'Leary11, Y. Patel1, D. Sudan1, N. Sulejmani7, B. Summers7, T. Schiano6

    1Duke, Durham, NC, 2Univ Miami, Miami, FL, 3NWU, Chicago, IL, 4UCLA, Los Angeles, CA, 5Seattle Child, Seattle, WA, 6Mt Sinai, NY, NY, 7Henry Ford, Detroit, MI, 8UNMC, Omaha, NE, 9Georgetown, Washington, DC, 10UPMC, Pittsburgh, PA, 11Dallas VAMC, Dallas, TX

    *Purpose: Review the management of immunosuppression (IS) for intestinal transplantation (IT) in the USA*Methods: A survey was created and sent via email to surgical directors…
  • 2019 American Transplant Congress

    First Report and Mechanistic Analysis of Operational Tolerance after Intestinal Transplant

    J. Weiner1, S. Moturi1, C. Ashokkumar2, K. Khan1, S. Kaufman1, R. Sindhi2, C. Matsumoto1, T. Fishbein1, A. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2University of Pittsburgh, Pittsburgh, PA

    *Purpose: Transplantation tolerance is a highly sought and rarely achieved state in clinical medicine. Defined as long-term stable and acceptable graft tolerance without immunosuppression and…
  • 2019 American Transplant Congress

    Promotion of Chimerism by Lymphohematopoietic Graft-versus-Host Responses in Patients Receiving Intestinal Transplantation

    J. Fu1, J. Zuber1, B. Shonts1, A. Obradovic1, K. Frangaj1, E. E. Waffarn1, S. Lau1, T. M. Savage1, S. Yang1, K. Rogers1, P. Satwani2, S. Ho1, Y. Shen3, A. Griesemer4, M. Martinez2, T. Kato4, M. Sykes1

    1Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, 2Department of Pediatrics, Columbia University, New York, NY, 3Department of Systems Biology, Columbia University, New York, NY, 4Department of Surgery, Columbia University, New York, NY

    *Purpose: Long-term multilineage chimerism often appears in blood following intestinal transplantation (ITx), usually without graft-versus-host disease (GVHD). Patients with donor T cell macrochimerism (≥4%) in…
  • 2019 American Transplant Congress

    Central Role of Graft Resident Memory T Cells in Pathogenesis of GVHD after Bowel Transplantation

    J. Weiner, N. Svetlicky, J. Schmidt, S. Moturi, O. Aguirre, J. Kang, M. Sadat, K. Khan, J. Hawksworth, C. Matsumoto, T. Fishbein, A. Kroemer

    MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Graft-versus-host disease (GVHD) is a relatively common and highly morbid complication after intestinal transplantation. Its pathophysiology remains poorly understood. Resident memory T cells (TRM)…
  • 2019 American Transplant Congress

    Deceased Donor Vascularized Abdominal Wall Allograft Procurement – Lessons Learned from Early Experiences

    J. A. Shah, D. L. Sudan, D. Erdmann, K. V. Ravindra

    Abdominal Transplant Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Vascularized abdominal wall allografts (AWA), which protect solid organs in patients with loss of abdominal domain or extensive abdominal wall damage, remain an essential…
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