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Articles tagged "Infection"

  • 2015 American Transplant Congress

    Infections After Alemtuzumab Induction: A Non Issue?

    A. Smith, M. John, I. Dortonne, A. Paramesh, M. Killackey, R. Zhang, B. Lee, J. Buell.

    Transplant Institute, Tulane University, New Orleans, LA.

    Background: Alemtuzumab is a powerful induction agent that depletes multiple lymphocyte cell lines resulting in leukopenia and/or neutropenia with concerns over infectious complications. This study…
  • 2015 American Transplant Congress

    BK Virus-Specific Polyfunctional CD8+ T Cells Predicts Successful Control of BK Viremia After Kidney Transplantation

    J. Schaenman,1 Y. Korin,2 T. Sidwell,2 F. Kandarian,2 N. Harre,2 P.-T. Pham,3 S. Bunnapradist,3 G. Danovitch,3 J. Veale,4 H. Gritsch,4 E. Reed.2

    1Medicine/Infectious Diseases, David Geffen School of Medicine (DGSOM) at UCLA, Los Angeles, CA; 2UCLA Immunogenetics Center, DGSOM at UCLA, Los Angeles, CA; 3Medicine/Nephrology, DGSOM at UCLA, Los Angeles, CA; 4Urology, DGSOM at UCLA, Los Angeles, CA.

    Introduction: BK Virus associated nephropathy (BKN) remains an important cause of graft loss after kidney transplantation. We hypothesized that analysis of the anti-BK virus immune…
  • 2015 American Transplant Congress

    The Impact of FcγRIIA, FcγRIIIA and C1QA Genes Polymorphism On Infectious Complications Following Renal Transplantation

    L. Das, Y. Tanaka, S. Verma, S. Shimizu, K. Ide, H. Ohdan.

    Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    AIM- Infectious complication is the leading cause of graft and patient loss after renal transplantation (RT). Under immunosuppressive condition when acquired immunity is suppressed, components…
  • 2015 American Transplant Congress

    Recreational and Lifestyle Infection Risks in Transplant Recipients

    R. Avery,1 D. Ostrander,1 S. Shoham,1 S. Alp,2 N. Lu,1 C. Cave,1 E. Kraus,3 K. Marr.1

    1Infectious Disease, Johns Hopkins, Baltimore, MD; 2Infectious Diseases and Clinical Microbiology, Hacettepe University Faculty of Medicine, Ankara, Turkey; 3Nephrology, Johns Hopkins, Baltimore, MD.

    Background: Counseling is commonly provided to transplant candidates and recipients concerning “strategies for safer living”, including ways to minimize infection risk.Methods: Patients enrolled in a…
  • 2015 American Transplant Congress

    Evaluation of the Gastrointestinal Tract as a Potential Route of Primary Polyomavirus Infection

    G. Huang,1 G. Zeng,2 Y. Huang,2 P. Randhawa.2

    1Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 2Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA.

    Detection of Polyomavirus(Py) DNA in metropolitan river water worldwide has led to the suggestion that primary viral infection can occur by the oral route. The…
  • 2015 American Transplant Congress

    Outcomes of Hepatitis C Virus (HCV) Treatment Following Liver Transplantation in the Era of Direct-Acting Antiviral Medications

    S. Baggett,1 D. Jones,1 M. Shoreibah.2

    1Department of Pharmacy, UAB Hospital, Birmingham, AL; 2Department of Gastroenterology, UAB Hospital, Birmingham, AL.

    BACKGROUND: The treatment of HCV is one of the most rapidly changing areas of medical practice. These agents have been shown to be safe and…
  • 2015 American Transplant Congress

    Adoptive Immunotherapy Using Activated NK Cells Ameliorates the FcγRIIIa Gene Polymorphism-Associated Susceptibility to Post Transplant Bloodstream Infection

    S. Shimizu, Y. Tanaka, H. Tazawa, S. Verma, H. Ohdan.

    Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.

    Background: At ATC 2014, we demonstrated that detection of single nucleotide polymorphisms (SNP) of FcγRIIIa helps predict the susceptibility of liver transplant (LT) recipients to…
  • 2015 American Transplant Congress

    Early Steroid Withdrawal and Infection Risk in Kidney Transplant Recipients

    S. Bae, L. Kucirka, C. Durand, B. Orandi, R. Avery, D. Segev.

    Johns Hopkins, Baltimore, MD.

    BACKGROUND: While early steroid withdrawal (ESW) is hypothesized to lower the risk of infection, previous studies failed to demonstrate this benefit. These were limited by…
  • 2015 American Transplant Congress

    Vaccination to Prevent the High Herpes Zoster Incidence After Renal Transplantation

    M. Kho,1 W. Weimar,1 D. Boveé,1 M. Boer-Verschragen,1 A. van der Eijk,2 N. van Besouw.1

    1Internal Medicine - Nephrology and Transplantation, Erasmus Medical Center, Rotterdam, Netherlands; 2Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.

    Introduction: Herpes zoster (HZ) is the clinical manifestation of varicella zoster virus (VZV) reactivation and occurs more frequently in people with a suppressed immune system.…
  • 2015 American Transplant Congress

    The Role of Quantitative Assay of Urinary Decoy Cells as a Screening and Follow-Up Tool in Renal Transplant Recipients With Polyomavirus BK Infection

    G. Huang, J. Qiu, C.-X. Wang, J.-G. Fei, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.

    Department of Organ Transplantation, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Polyomavirus BK nephropathy (BKVN) is an important infectious complication in kidney transplant patients. Urinary cytology is effective for early diagnosis of BKVN. However, quantitative assay…
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