Articles tagged "Infection"

2021 American Transplant Congress
Letermovir Prophylaxis in Solid Organ Transplant – CMV Breakthrough and Tacrolimus Drug Interaction
R. Winstead¹, D. Kumar¹, A. Brown¹, I. Yakubu¹, C. Song¹, L. Thacker², G. Gupta¹
¹Virginia Commonwealth University Health, Richmond, VA, ²Virginia Commonwealth University, Richmond, VA
*Purpose: Valganciclovir is the preferred drug for cytomegalovirus (CMV) prophylaxis in solid organ transplantation. A limitation to its use is profound myelosuppression. Letermovir is a…
2021 American Transplant Congress
The Impact of Covid-19 Pandemic on Living Donor Liver and Renal Transplantations in Japan: A Nationwide Survey
S. Yamanaga¹, T. Hibi², R. Osawa³, K. Yuzawa⁴, H. Egawa⁵, K. Kuramitsu⁶
¹General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan, ²Pediatric Surgery and Transplantation, Kumamoto University, Kumamoto, Japan, ³Infectious disease, Kameda medical center, Kamogawa, Japan, ⁴Transplant Surgery, Mito Medical Center, Higashiibaraki District, Japan, ⁵Gastrointestinal Surgery, Tokyo Women's Medical University Hospital, Shinjyuku-ku, Japan, ⁶HBP surgery, Kobe University, Kobe, Japan
*Purpose: COVID-19 brought a huge impact on the field of organ transplantation. On 6th March, the Japan Society for Transplantation (JST) COVID-19 task force published…
2021 American Transplant Congress
Transcriptomics and Proteomics Profiling of Complement Pathway (cp) Proteins in Biopsies With Polyomavirus Bk Nephropathy (bkvn)
P. Randhawa¹, F. Fei², Y. Huang¹, G. Tseng³, K. Xiao⁴
¹Departments of Pathology, Pittsburgh, PA, ²Pharmacology and Chemical Biology, Pittsburgh, PA, ³Biostatistics, Pittsburgh, PA, ⁴Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Late stage BKVN can show C4d as well as classic immune complex deposits in the tubular basement membranes (Bracamonte et al. Am J Transplant…
2021 American Transplant Congress
Influence of Immunosuppressant Management on Mortality in Kidney Transplant Recipients Hospitalized with COVID-19
Y. Fenig, A. Santeusanio, M. Menon, C. Liu, M. Rana, R. Shapiro
Mount Sinai Hospital, New York, NY
*Purpose: Kidney transplant recipients are thought to be at high risk for mortality from COVID-19 due to the necessity for chronic immunosuppressive therapy to prevent…
2021 American Transplant Congress
Sars-cov-2 versus Non-sars-cov-2 Infection Among Solid Organ Transplant Recipients: Case Control Study
M. A. Mendoza¹, M. Raja¹, S. Anjan¹, S. C. Curel², G. Rosello³, A. Fernandez¹, A. Chandorkar⁴, C. O'Brien⁵, A. Phancao⁵, N. Sinha¹, R. Vianna¹, M. Loebe¹, C. Gaetano¹, J. Simkins¹, M. Morris¹, L. Abbo¹, J. Camargo¹, G. Guerra¹, Y. Natori¹
¹Department of Medicine, University of Miami, Miami, FL, ²Miller School of Medicine, University of Miami, Miami, FL, ³University of Miami, Miami, FL, ⁴University of Minnesota, Minneapolis, MN, ⁵Miami Transplant Institute, University of Miami, Miami, FL
*Purpose: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been raging since the end of 2019. The clinical differences between non-SARS-CoV-2 coronavirus and SARS-CoV-2…
2021 American Transplant Congress
Impact of Early versus Late Ureteric Stent Removal and Antibiotic Prophylaxis on Urinary Tract Infection Incidence in Kidney Transplant Adult Recipients
K. Althiab¹, B. Alqahtani², R. Alotaibi³, R. Alhussein³, R. Almuhiteb², L. Alnajjar², M. Alqahtani², K. Bin Saad⁴, W. Ohali⁴, A. Tamimi⁴, M. N. Almarastani⁴, S. Kashkoush⁴, G. Aboalsameh⁴, M. Shaheen⁴, M. Tawhari⁴, A. Altheaby⁴, Z. Arabi⁵
¹Pharmaceutical Care Services, King Abdulaziz Medical Center, Riyadh, Saudi Arabia, ²College of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, ³bCollege of Pharmacy, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia, ⁴Organ Transplant Center, King Abdulaziz Medical Center, Riyadh, Saudi Arabia, ⁵King Abdulaziz Medical Center, Riyadh, Saudi Arabia
*Purpose: To investigate the impact of early Vs. late ureteric stent removal while utilizing various antibiotic prophylaxis regimens on UTI in renal transplant recipients. *Methods:…
2021 American Transplant Congress
Clinical and Pathological Features of Lobar Nephronia in Renal Allograft
Y. Wang¹, Z. Yan¹, Y. Liu¹, Y. Zhou¹, Y. He¹, W. Zeng¹, R. Xia¹, W. Deng¹, J. Xu¹, C. Wu², Y. Miao¹
¹Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, China, ²Department of Urology and Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
*Purpose: Lobar nephronia (acute focal nephritis) is a rare form of nephritis which can be presented as a renal mass and misdiagnosed as renal cancer,…
2021 American Transplant Congress
Pediatric Kidney Transplant Recipients Frequently Experience Utis Regardless of Esrd Etiology
E. Spiwak, C. Nailescu, A. Schwaderer
Indiana University Department of Pediatrics Division of Nephrology, Indianapolis, IN
*Purpose: Urinary tract infections (UTIs) remain the most common type of infectious complication experienced by renal allograft recipients. UTIs in transplant patients most commonly occur…
2021 American Transplant Congress
Panic in the Pandemic: A Medical Decision Analysis Examining When Kidney Transplant Programs Should Close
A. J. Vinson¹, B. Kiberd², K. Tennankore¹
¹Nova Scotia Health Authority Division of Nephrology, Departm, Halifax, NS, Canada, ²Dalhousie University, Halifax, NS, Canada
*Purpose: Pandemics greatly interfere with overall health care delivery as resources are diverted to combat the crisis. Kidney transplantation programs were closed temporarily during the…
2021 American Transplant Congress
T-Cell Responses in Solid Organ Transplant Recipients with SARS-CoV-2 Infection
V. H. Ferreira, T. M. Marinelli, T. Ku, M. Ierullo, B. Majchrzak-Kita, I. Bahinskaya, N. Pinzon, A. Humar, D. Kumar
University Health Network, Toronto, ON, Canada
*Purpose: Preliminary data suggest solid organ transplant (SOT) recipients may be at high-risk for developing severe COVID-19. This may be due in part to alterations…