Articles tagged "Infection"

2021 American Transplant Congress
Early Detection of SARS-CoV-2 and Other Infections in Solid Organ Transplant Recipients and Household Members Using Wearable Devices
E. H. Li¹, E. Mukhtar¹, E. D. Elftmann¹, F. R. Eweje¹, H. Gao¹, L. I. Ibrahim¹, R. G. Kathawate¹, A. C. Lee¹, K. A. Moore¹, N. Nair¹, S. Amaral², M. Snyder³, B. J. Keating¹
¹Department of Surgery, Penn Transplant Institute, Division of Transplantation, Philadelphia, PA, ²Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, ³Department of Genetics, Stanford University, Palo Alto, CA
*Purpose: Wearable devices that measure physiological parameters have shown utility for detecting infections such as influenza and recently COVID-19 up to 10 days before clinical…
2021 American Transplant Congress
Lung Transplant Recipients with Severe Acute Respiratory Syndrome-Coronavirus 2 Infection and Asymptomatic Carriers Waiting for Lung Transplantation Induce Circulating Exosomes with Severe Acute Respiratory Syndrome-Coronavirus 2 Spike Protein S2
S. Bansal, S. Tokman, T. Fleming, M. Smith, R. Bremner, T. Mohanakumar
St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Exosomes are vesicles released by cells into body fluids. We demonstrated increased circulating exosomes with lung self-antigens (Collagen V, Kα1 Tubulin) and viral antigens…
2021 American Transplant Congress
Dysregulation of Immune Cell Glycolysis and Oxidative Phosphorylation Correlates with Development of Pre-liver Transplant Immune Dysfunction and Post-transplant Mortality
G. Panayotova¹, L. Jin¹, A. Lemenze¹, S. Simonishvili¹, Y. Qin¹, L. Minze², G. Dikdan¹, F. Paterno¹, X. C. Li², M. Ghobrial², J. V. Guarrera¹, K. E. Lunsford¹
¹Transplant Surgery, Rutgers NJMS, Newark, NJ, ²Transplant Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Cirrhosis-related immune dysfunction contributes to early morbidity and mortality following liver transplant (LT). We have previously identified a pre-LT biomarker panel, the immune frailty…
2021 American Transplant Congress
Relationship Between Tacrolimus Blood Levels and Covid-19 Pandemic in Kidney Transplant Recipients
T. Inoue¹, K. Unagami,², A. Ishiwatari³, T. Kanzawa³, T. Shimizu³, K. Omoto³, M. Inui³, T. Suzuki¹, H. Ishida⁴, K. Tanabe³
¹Department of Nephrology, Kameda Medical Center, Chiba Kamogawa, Japan, ²Department of Organ Transplant Medicine, Tokyo Women’s Medical University, Tokyo, Japan, ³Department of Urology, Tokyo Women’s Medical University, Tokyo, Japan, ⁴Department of Organ transplant medicine, Tokyo Women’s Medical University, Tokyo, Japan
*Purpose: The novel coronavirus 2019 infection (COVID-19) caused a pandemic, prompting Tokyo, Japan, to restrict on the free movement of people in March 2020. Kidney…
2021 American Transplant Congress
Covid-19 Caseload and Management Practices Vary by Program-Level Factors: A Multinational Survey Study
S. Sandal¹, B. Boyarsky², P. Chiang², A. Massie², D. Segev², M. Cantarovich¹
¹McGill University, Montreal, QC, Canada, ²Johns Hopkins University, Baltimore, MD
*Purpose: During the pandemic, the COVID-19 patient caseload (CPC) is thought to be highly variable and likely dependant on the cumulative COVID-19 incidence (CCI) of…
2021 American Transplant Congress
Intensive Monitoring and Early Treatment for Urinary Infection in Renal Transplant Recipients Reduces Readmission and Sepsis
A. Patel, S. Desai, B. R. Schleich, M. Wynd, T. Carrea, Y. Yushkov, S. Geatrakas, N. White, R. Luongo, R. Sosnicki, V. Wadhera, D. Serur, M. J. Goldstein
Organ Transplant, Hackensack University Medical Center, Hackensack, NJ
*Purpose: Urinary tract infection (UTI) is a common renal transplant (RT) complication that is observed in up to 60-70% of RT recipients and may affect…
2021 American Transplant Congress
Tolerability of Mycophenolate Mofetil in Elderly Kidney Transplant Recipients: A Retrospective Cohort Study
S. Witek¹, G. Malat², D. Sawinski², C. Sammons², C. LaFratte¹, A. Forte¹, R. Samudralwar¹, S. Lyle¹, J. Rashid¹, J. Trofe-Clark²
¹Dept of Pharmacy, Hospital of the Univ of Pennsylvania, Philadelphia, PA, ²Penn Transplant Institute, Hospital of the Univ of Pennsylvania, Philadelphia, PA
*Purpose: Optimal immunosuppression in elderly kidney transplant recipients (KTRs) is not well-defined, with MMF being poorly tolerated at standard doses. This study aims to compare…
2021 American Transplant Congress
Outcomes of Covid 19 in Candidates Waitlisted for Kidney and Pancreas Transplantation
R. El-Rifai¹, S. Riad¹, R. Belina², A. Matas²
¹Medicine, University of Minnesota, Minneapolis, MN, ²Surgery, University of Minnesota, Minneapolis, MN
*Purpose: The COVID 19 pandemic has posed new challenges to transplant centers. The impact has been detrimental on wait-listed ESKD patients, reducing their access to…
2021 American Transplant Congress
COVID-19 in the Kidney Transplant Waitlist Population
A. C. Johnson¹, C. P. Larsen¹, H. Gebel², R. Bray²
¹Surgery, Emory University, Atlanta, GA, ²Pathology, Emory University, Atlanta, GA
*Purpose: Through banked serum samples from transplant candidates across Georgia, we characterize the prevalence, timing, and duration of SARS-CoV-2 seropositivity and investigate the impact on…
2021 American Transplant Congress
Early Stent Removal in Kidney Transplant Recipients – A Quality Improvement Project
V. Rohan, N. Pilch, M. Altiti, S. Nadig, A. Lin, D. DuBay, P. Baliga
Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Ureteric Stent placement is a is common practice at the time of kidney transplantation to reduce the incidence and severity of Major Urological Complications…