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American Transplant Congress abstracts

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Articles tagged "Infection"

  • 2021 American Transplant Congress

    The Metagenomic Landscape of Renal Transplant

    A. Johnson1, G. Karadkhele2, C. Larsen2

    1Emory University, Atlanta, GA, 2Surgery, Emory University, Atlanta, GA

    *Purpose: The selective targeting of T cells in transplant immunosuppression medications leads to a high rate of viral infections. Different immunosuppression regimens have been shown…
  • 2021 American Transplant Congress

    Immunosuppression is Not Associated with High-risk Immunologic Parameters in Transplant Recipients with the Sars-cov2 Virus

    S. Merl, R. Jones, B. Shonts, D. Rust, M. Sykes, J. Weiner

    Medicine/Surgery, Columbia University Medical Center, New York, NY

    *Purpose: The factors associated with severe COVID-19 disease in transplant patients are poorly understood. Despite concern that patients with weakened immune responses have increased risk…
  • 2021 American Transplant Congress

    An Evaluation of Pjp Prophylaxis and Anemia Among Renal Transplant Recipients

    J. Hedvat, N. Poladi, D. Salerno, G. Dube, N. Lange

    NewYork-Presbyterian Hospital, New York, NY

    *Purpose: Dapone and atovaquone are therapeutic options for PJP prophylaxis in renal transplant recipients. The objective of this study was to evaluate the incidence of…
  • 2021 American Transplant Congress

    Covid-19 Reinfection in a Kidney Transplant Patient

    Z. Saeed Zafar, D. Malhotra

    Nephrology, Yale School of Medicine, New Haven, CT

    *Purpose: Several cases have demonstrated positive SARS-CoV-2 PCR testing in patients who were initially shown to have cleared the infection. These reinfections may represent new…
  • 2021 American Transplant Congress

    Covid 19 Re-infection versus Re-activation in Two Renal Transplant Patients

    L. Liriano-Ward, Y. Al Azzi, R. Bartash, C. Pynadath, M. Ajaimy, P. Loarte, J. Graham, S. Greenstein, M. Kinkhabwala, J. Rocca, E. Akalin

    Montefiore Medical Center, New York, NY

    *Purpose: Rare cases of potential COVID 19 re-infection have been reported throughout the world.*Methods: We describe two renal transplant recipients with possible SARS-COV-2 re-infection.*Results: Patient…
  • 2021 American Transplant Congress

    Dosing Weight of Rabbit Antithymocyte Globulin and Outcomes Among Kidney Transplant Patients Treated for Rejection

    C. Patton, K. Cunningham, C. D'Agostino, A. Novak, M. Kapugi, K. Lang, C. Kane

    Pharmacy, Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Rabbit antithymocyte globulin (rATG) is FDA approved for kidney transplant induction therapy and treatment of T-cell mediated rejection (TCMR). While prior studies comparing dosing…
  • 2021 American Transplant Congress

    Impact of Bacterial Infection on HLA Allosensitization Among Kidney Recipients on the Waitlist

    D. P. Cina1, K. R. Sherwood2, S. Dobrer2, J. Wong3, F. Fenninger2, M. Kadatz4, P. Keown4, J. Lan4

    1Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada, 2University of British Columbia, Vancouver, BC, Canada, 3Department of Laboratory Medicine, Vancouver General Hospital, Vancouver, BC, Canada, 4Department of Nephrology, University of British Columbia, Vancouver, BC, Canada

    *Purpose: The clinical relevance of HLA allosensitization associated with bacterial infection remains poorly defined. The primary objective of this study is to determine the incidence,…
  • 2021 American Transplant Congress

    Early Detection of SARS-CoV-2 and Other Infections in Solid Organ Transplant Recipients and Household Members Using Wearable Devices

    E. H. Li1, E. Mukhtar1, E. D. Elftmann1, F. R. Eweje1, H. Gao1, L. I. Ibrahim1, R. G. Kathawate1, A. C. Lee1, K. A. Moore1, N. Nair1, S. Amaral2, M. Snyder3, B. J. Keating1

    1Department of Surgery, Penn Transplant Institute, Division of Transplantation, Philadelphia, PA, 2Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, 3Department of Genetics, Stanford University, Palo Alto, CA

    *Purpose: Wearable devices that measure physiological parameters have shown utility for detecting infections such as influenza and recently COVID-19 up to 10 days before clinical…
  • 2021 American Transplant Congress

    Lung Transplant Recipients with Severe Acute Respiratory Syndrome-Coronavirus 2 Infection and Asymptomatic Carriers Waiting for Lung Transplantation Induce Circulating Exosomes with Severe Acute Respiratory Syndrome-Coronavirus 2 Spike Protein S2

    S. Bansal, S. Tokman, T. Fleming, M. Smith, R. Bremner, T. Mohanakumar

    St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: Exosomes are vesicles released by cells into body fluids. We demonstrated increased circulating exosomes with lung self-antigens (Collagen V, Kα1 Tubulin) and viral antigens…
  • 2021 American Transplant Congress

    Dysregulation of Immune Cell Glycolysis and Oxidative Phosphorylation Correlates with Development of Pre-liver Transplant Immune Dysfunction and Post-transplant Mortality

    G. Panayotova1, L. Jin1, A. Lemenze1, S. Simonishvili1, Y. Qin1, L. Minze2, G. Dikdan1, F. Paterno1, X. C. Li2, M. Ghobrial2, J. V. Guarrera1, K. E. Lunsford1

    1Transplant Surgery, Rutgers NJMS, Newark, NJ, 2Transplant Surgery, Houston Methodist Hospital, Houston, TX

    *Purpose: Cirrhosis-related immune dysfunction contributes to early morbidity and mortality following liver transplant (LT). We have previously identified a pre-LT biomarker panel, the immune frailty…
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