2016 American Transplant Congress
After Alemtuzumab Induction, Tac+MMF Is Superior to CsA+MMF in Pediatric Kidney Transplantation.
1Boris Petrovsky SCS, Moscow, Russian Federation; 2Mount Sinai Hospital, New York, NY.
Introduction: Recipient parenchymal lymphatic cells are crucial for direct and indirect pathways of allorecognition. We proposed that administering alemtuzumab several weeks pretransplantation could eradicate peripheral…2016 American Transplant Congress
Implementation of a Risk Stratified Approach for Prevention of Hepatitis B Reactivation Post Kidney Transplant.
A large percentage of patients with end stage renal disease are known to be Hepatitis B virus (HBV) positive. A 2015 consensus guideline on use…2016 American Transplant Congress
Outcomes in Elderly Renal Transplant Recipients Using Thymoglobulin or Interleukin-2 Receptor Antagonist Induction.
1Pharmacy, University of Illinois, Chicago; 2Transplant Surgery, University of Illinois, Chicago.
Background: Approximately 20% of all renal transplants performed in the US in 2014 occurred in elderly patients. Elderly patients are known to be at higher…2016 American Transplant Congress
A Retrospective Analysis of Rabbit Antithymocyte Globulin Dosing, MELD, Race, and Weight on Infection and Rejection Rates in Liver Transplantation.
Department of Pharmacy, Stanford Health Care, Stanford, CA.
INTRODUCTION: Rabbit antithymocyte globulin (rATG) use in liver transplantation is uncommon. At our center, induction therapy is comprised of rATG dosed at 1 – 2…2016 American Transplant Congress
The Effect of Donor Age on Acute Rejection Age – The Clinical Impact of Donor Immuno-Senescence in the Modern Immunosuppressive Era.
Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom.
Experimental work has shown that donor age may alter the immune response of the recipient so that older donor grafts elicit a stronger response in…2016 American Transplant Congress
Induction with T-cell Depletional Agents Is Safe and Efficacious in the Very Elderly Kidney Transplant Recipients: An Analysis of the OPTN Database.
Virginia Commonwealth University, Richmond, VA.
Background: Kidney transplantation is increasingly being offered to the very elderly (Age>70 years) kidney transplant recipients. Previous studies analyzing the effect of induction immunosuppression in…2016 American Transplant Congress
Here Comes the Sun: Industry's Payments to Transplant Physicians.
Background: The Open Payments Program (OPP) was implemented to publicly disclose industry payments to physicians, enabling patients to be aware of conflicts of interests. We…2016 American Transplant Congress
PD-L1/PD-L2-Expressing B-1a Cells Inhibit Allo-Reactive T Cells in Mice.
Donor lymphocyte infusion (DLI) induces donor-specific hypo responsiveness or immune-tolerance among allo-reactive T cells in different organ transplantation models. However, the optimal cell source or…2016 American Transplant Congress
Comparison of De Novo Donor Specific Antibody Formation for Kidney Transplant Recipients Induced with Thymoglobulin or Basiliximab.
Division of Transplantation, University of Southern California, Los Angeles, CA.
Background: Thymoglobulin (ATG) and basiliximab (Bas) induction are commonly used therapies to prevent allograft rejection in kidney transplant recipients (KTx). Formation of donor specific antibodies…2016 American Transplant Congress
Do Powerful Induction Antibodies Increase Post Renal Transplant Infections?
Transplant Institute, Tulane University School of Medicine, New Orleans, LA.
Purpose: Infection is one of the most common and costly complications of solid organ transplantation. Alemtuzemab (AL) is a powerful antibody that significantly reduced rejection…
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