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Articles tagged "Induction therapy"

  • 2020 American Transplant Congress

    Thymoglobulin (ATG) Induction vs. Campath vs. Simulect in DCD Kidneys in UK; Induction Regimes Play a Role after All

    A. Asderakis1, T. Sabbah1, J. Watkins2, L. Szabó1, D. Elker1, A. M. Ilham1, E. Ablorsu1, M. Stephens1, U. Khalid1, R. Chavez1

    1Cardiff Transplant Unit,, University Hospital of Wales, Cardiff, United Kingdom, 2Infection and Immunity, Cardiff University, Cardiff, United Kingdom

    *Purpose: Controlled DCD kidneys have increased dramatically in UK. They suffer from a higher rate of DGF and, often in UK, come from older donors…
  • 2020 American Transplant Congress

    Comparison of Clinical Outcomes of Induction Regimens in Patients Undergoing Liver Transplantation for Acute Liver Failure

    C. M. Anugwom1, J. Parekh2, C. Hwang3, M. MacConmara3, W. M. Lee4, T. M. Leventhal1

    1Gastroenterology, Hepatology and Nutrition, University of Minnesota Medical Center, Minneapolis, MN, 2Department of Surgery, University of California, San Diego, San Diego, CA, 3Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, 4Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX

    *Purpose: Spontaneous survival rates in acute liver failure (ALF) are vastly improved by liver transplantation (LT). However, the value of induction agents beyond steroids continues…
  • 2020 American Transplant Congress

    Anti-T Lymphocyte Immunoglobulins versus Basiliximab in Highly Sensitized Kidney-Transplant Patients without Preformed DSAs: The Satir Study

    N. Kamar1, L. Couzi2, L. Albano3, A. Durrbach4, V. Pernin5, L. Esposito1, M. Lequintrec5, P. Merville2, A. Del Bello1

    1Toulouse University Hospital, Toulouse, France, 2Bordeaux University Hospital, Bordeaux, France, 3Nice University Hospital, Nice, France, 4Henri Mondor University Hospital, Paris, France, 5Montpellier University Hospital, Montpellier, France

    *Purpose: Two prospective studies that were performed before the era of highly sensitive solid-phase assays have shown a lower incidence of acute rejection in highly…
  • 2020 American Transplant Congress

    Impact of Immunogenicity on Kidney Allograft Survival in Patients Treated with Induction Therapy

    R. Michael, B. Mierzejewska, D. Bekbolsynov, J. Ortiz, O. Ekwenna, S. Stepkowski

    University of Toledo, Toledo, OH

    *Purpose: The induction therapy is currently used in the majority of kidney transplant recipients, regardless of their level of donor/recipient compatibility. We examined whether lower…
  • 2020 American Transplant Congress

    Comparison of 1-Year Incidence of De Novo Donor Specific Antibodies between Thymoglobulin and Alemtuzumab Induction in Kidney Transplantation

    J. P. Knorr, C. Kallis, D. A. Portley, A. Jeyarajasingam, P. W. Lai, G. Bradauskaite, K. Khanmoradi

    Transplant Nephrology, Einstein Medical Center, Philadelphia, PA

    *Purpose: Development of de novo donor specific antibodies (dnDSA) after kidney transplantation (KTx) has been associated with acute and chronic antibody-mediated rejection, transplant glomerulopathy and…
  • 2020 American Transplant Congress

    Enough Initial Tacrolimus Blood Concentration is Crucial Even with Additional Everolimus in Corticosteroid Early Withdrawal Regimen for Kidney Transplant Recipients

    H. Sasaki1, T. Tanabe1, H. Higuchi1, T. Tsujimoto2, H. Harada1

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan, 2Pharmacy, Sapporo City General Hospital, Sapporo, Japan

    *Purpose: Everolimus (EVR) in combination with low-dose calcineurin inhibitor has been demonstrated in clinical trials to have comparable efficacy in low immunological risk kidney transplant…
  • 2020 American Transplant Congress

    Pediatric Primary Kidney Transplant Recipients Outcomes by Immunosuppression Induction Received in the United States

    S. M. Riad1, S. Jackson2, A. Matas3, S. Chinnakotla3, P. Verghese4

    1University of Minnesota, Minneapolis, MN, 2Complex Care Analytics, Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN, 4Pediatrics, University of Minnesota, Minneapolis, MN

    *Purpose: Induction immunosuppression types for pediatric transplant recipients vary widely by transplant centers. We sought to study the impact of different induction types on recipients…
  • 2020 American Transplant Congress

    Basiliximab vs Antithymocyte Globulin Induction with Early Steroid Withdrawal in Kidney Transplant Recipients: Early Rejection Outcomes

    A. Szczepanik1, C. Burrelli1, A. Bixby1, K. Yadav2, K. Chavin2

    1Pharmacy, University Hospital Cleveland Medical Center, Cleveland, OH, 2Surgery, University Hospital Cleveland Medical Center, Cleveland, OH

    *Purpose: Steroid withdrawal within the first month of kidney transplant (KT) remains controversial and has demonstrated a higher risk of acute rejection. The impact of…
  • 2020 American Transplant Congress

    Renal Transplant Induction Therapy Safety Outcomes Comparison

    R. M. Hofmann1, J. Combs2, K. J. Schmidt3, T. Dyckman4

    1Nephrology, Renal Associates of West Michigan, Grand Rapids, MI, 2Pharmacy/Transplant, Mercy Health St. Mary's, Grand Rapids, MI, 3Pharmacy, Ferris State University College of Pharmacy, Big Rapids, MI, 4Pharmacy, Mercy Health St. Mary's, Grand Rapids, MI

    *Purpose: Induction immunosuppression with alemtuzumab and rabbit anti-thymocyte globulin (r-ATG) reduces acute rejection following kidney transplantation. Efficacy is thought to be similar between the agents…
  • 2020 American Transplant Congress

    Depletional Induction Improves Kidney Graft and Patient Survival in Recipients with a Previous Liver Transplant in the United States

    S. M. Riad1, N. Lim1, S. Jackson2, A. Matas3, J. Lake1

    1Medicine, University of Minnesota, Minneapolis, MN, 2Fairview Health Services, Minneapolis, MN, 3Surgery, University of Minnesota, Minneapolis, MN

    *Purpose: Induction choices for kidney-after-liver transplant recipients are variable. We examined the impact of kidney induction types on kidney graft and patient survival in liver…
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