2017 American Transplant Congress
Evaluating T Cell Repopulation Post Alemtuzumab Induction with a Belatacept-Based Regimen.
Department of Surgery, Duke University, Durham, NC
We reported that alemtuzumab induction followed by belatacept-sirolimus based immunosuppression effectively prevents costimulation blockade resistant rejection (CoBRR). This study investigates the phenotypic characteristics of repopulating…2017 American Transplant Congress
Alemtuzumab Induction and Belatacept Maintenance in Marginal Pathology Renal Allografts.
University of Maryland, Baltimore
Background: The potential for improved outcomes with CNI avoidance may be important for kidneys with an increased likelihood of impaired graft function. We performed a…2017 American Transplant Congress
Clinical and Pathologic Characteristics of Acute Rejection After Alemtuzumab Induction in Kidney Transplant Recipients.
Background: Alemtuzumab induction (AZI) can be used for early steroid withdrawal in kidney transplant (KTx) recipients. There is evidence that AZI-induced lymphocyte depletion leads to…2017 American Transplant Congress
The Outcome of 0 Mismatch Kidney in Pediatric Population with High Immunologic. The Impact of Induction Therapy. An Analysis of UNOS Database.
Surgery, State University New York, Syracuse, NY
Background: 0 mismatch kidneys have superior outcomes in primary transplant recipient. We performed Analysis UNOS database to determine the outcome of high PRA transplant pediatric…2017 American Transplant Congress
Does Choice of Induction Agent Affect Outcomes in Kidney Transplants from Deceased Donors with Acute Kidney Injury and Prolonged Cold Ischemia Time?
Nephrology, Columbia University Medical Center, New York, NY
Kidneys with acute kidney injury (AKI) have a higher rate of DGF but similar outcomes to kidneys without AKI, although most data are with kidneys…2017 American Transplant Congress
Liver Transplantation Outcomes Using Anti-Thymocyte Globulin Induction in Patients with Autoimmune Hepatitis.
Transplantation Surgery, Virginia Commonwealth University, Richmond, VA
Background: The use of rabbit anti-thymocyte globulin (ATG) induction in high immunological risk patients with autoimmune hepatitis (AIH) could lower the rejection rates after liver…2017 American Transplant Congress
Understanding the Role of Induction Agents in Older versus Younger Kidney Transplant Recipients.
Johns Hopkins University, Baltimore, MD
Background: There has been an increase in the number of older (over 65) KT recipients. Aging-related changes such as differences in immune senescence may influence…2017 American Transplant Congress
Renal Transplant Patient Outcomes Following Plasmapheresis, Thymoglobulin, and Rituximab Induction for High Risk DSA Positive Recipients.
Background: Kidney transplantation is associated with improved survival and quality of life relative to dialysis for patients with end-stage renal disease (ESRD). Patients who are…2017 American Transplant Congress
De Novo Malignancy Occurrence After Kidney Transplantation in HLA-Sensitized Patients Treated with B-Cell Targeting Therapy.
Management of high risk transplantations in patients with preformed DSA still remains a dilemma. Many groups propose to increase the immunosuppression in these patients by…2017 American Transplant Congress
Impact of T-Cell Depletion on CMV-Specific Memory T and B Cell Homeostatic Proliferation After Kidney Transplantation.
Human CMV infection is the most common opportunistic infection after kidney transplantation, with a negative impact on kidney allograft outcome. Transplant recipients are at higher…
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