2015 American Transplant Congress
The Use of Eculizumab to Treat the Highly Sensitized Patient Awaiting Heart Transplant
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: Highly sensitized patients (pts) awaiting heart transplantation remain a significant challenge due to prolonged often prohibitive wait times for suitable organs and increased rejection…2015 American Transplant Congress
The Molecular Landscape of Atrophy-Fibrosis in Human Kidney Transplants: The Dominant Role of Acute Parenchymal Injury
University of Alberta, Edmonton, Canada.
We studied the effect of time post-transplant on atrophy-fibrosis (AF) and molecular associations with AF in 703 kidney transplant indication biopsies (bx) 3 days to…2015 American Transplant Congress
Serum Creatinine Is Most Predictive of Graft Loss in Late Antibody Mediated Rejection
Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.
Development of acute antibody mediated rejection (AMR) is associated with graft loss and can occur both early (< 3 months) and late (> 3 months)…2015 American Transplant Congress
Immunodeficiency Assessment in Pediatric Intestinal Failure Patients
Intestinal failure (IF) is a clinical condition for which intestinal transplantation may be indicated. Patients without enteral autonomy have an increased risk of malnutrition which…2015 American Transplant Congress
Characteristics of IgGs Produced in Neu5Gc and α1-3 Gal Double Knock-Out Pigs
Xenotransplantation offers a large number of potential applications, including solid organs, pancreatic islets, acellular tissues such as heart valves and skin grafts, and new bioreagents…2015 American Transplant Congress
Anti-Thymocyte Globulin Induction in Infected Mechanical Circulatory Support Patients: Is It Safe?
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: The use of mechanical circulatory assist devices (MCSD) have been increasing over the past several years. Driveline infections (DLI) are one of the most…2015 American Transplant Congress
Plasmapharesis, Intravenous Immunoglobulin and Rituximab Successfully Treat Recurrent Progressive Familial Intrahepatic Cholestasis Type 2 (PFIC-2) After Liver Transplantation
Background:Allo-immune mediated BSEP dysfunction may occur after liver transplantation in PFIC2 patients leading to a PFIC2 like phenotype. The IgG antibodies are reactive toward a…2015 American Transplant Congress
The Effects of Donor Specific Anti- Human Leukocyte Antigen Antibodies Late After Heart Transplantation
Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: The development of anti-HLA antibodies following heart transplantation has been associated with poor outcomes, including lower survival and increased risk for the development of…2015 American Transplant Congress
CMV IgG Provides Similar Anti-CMV Efficacy as Valganciclovir in High-Risk Organ Transplant Recipients, With Reduced Costs
Abdominal organ transplants at high risk for CMV infection (D+/R-) remain a difficult cohort to prevent late CMV infection despite prolonged valganciclovir (VGC) administration. Administration…
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