2022 American Transplant Congress
The Evolution of Hypogammaglobulinemia in Kidney Transplant Recipients and Its Associated Risk Factors
*Purpose: Hypogammaglobulinemia (HGG) has been extensively studied to identify a biological marker for infection. According to Florescu et al. (2013), a meta-analysis of 18 clinical…2022 American Transplant Congress
Desensitization Protocol Consisting of High-Dose Intravenous Immunoglobulin, Plasmapheresis, and Rituximab in Highly Sensitized Kidney Transplant Recipients
Nagoya Daini Red Cross Hospital, Nagoya, Japan
*Purpose: In HLA incompatible kidney transplantation, donor-specific HLA antibody often causes antibody-mediated rejection (AMR). To prevent AMR, we adopted a preoperative desensitization protocol including high-dose…2022 American Transplant Congress
Daratumumab Therapy Achieves Dialysis Independence in Kidney Transplant Recipients with Resistant Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits
The Ohio State University, Columbus, OH
*Purpose: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is a unique cause for monoclonal gammopathy of renal significance with overall poor prognosis. Patients are frequently…2022 American Transplant Congress
Immunoglobulin M (IgM) Inhibits Replication of SARS-CoV-2 In Vero E6 Cells In Vitro and Delays Disease in K18-hACE2 Mice Infected with SARSCoV-2 In Vivo
*Purpose: To determine if IgM has a direct effect in preventing SARS-CoV-2 replication in Vero E6 cells, and delaying or preventing disease in infected K18-hACE2…2022 American Transplant Congress
Management of Hepatitis B Positive Donors in Liver Transplant
1Pharmacy, UAB, Birmingham, AL, 2UAB, Birmingham, AL
*Purpose: In an effort to expand the pool of solid organ transplant donors, patients with end stage liver disease may receive an organ from a…2022 American Transplant Congress
Outcome of Donor Derived and Community Acquired West Nile Infections in Kidney Transplant Recipients
1Renal Medicine Associates, Albuquerque, NM, 2Presbyterian Health Services, Albuquerque, NM
*Purpose: Donor derived West Nile Virus(WNV) Infections can occur but rare. We are presenting four cases that were seen at our transplant center*Methods: Case 1:…2021 American Transplant Congress
Post-Transplant Idiopathic Immune Complex Glomerulonephritis
University of Wisconsin, Madison, WI
*Purpose: The appropriate treatment for post-kidney transplant immune complex glomerulonephritis (ICGN) of unknown cause is unclear.*Methods: From 01/2004 to 12/2018, 71 patients were diagnosed with…2021 American Transplant Congress
Outcomes of IVIG Monotherapy for Donor-Specific Antibodies After Lung Transplantation
Vanderbilt University Medical Center, Nashville, TN
*Purpose: De novo donor-specific antibodies (DSA) are a risk factor for antibody mediated rejection (AMR) and poor clinical outcomes after lung transplant (LT). Intravenous immune…2021 American Transplant Congress
The Role of Notch2 in Antibody-mediated Alloimmune Response
*Purpose: Antibody mediated rejection is the leading cause of chronic allograft rejection. Developing a novel therapeutic target to inhibit chronic rejection is an urgent need…2021 American Transplant Congress
Use of a Novel Bead-based Assay to Measure the Impact of Imlifidase on ABO IgG Antibodies
*Purpose: The accurate assessment and measurement of ABO antibodies (ABO-Ab) is a critical component of ABO-incompatible (ABOi) transplantation. ABO-Ab comprise both IgG and IgM, which…
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