Articles tagged "Image analysis"

2018 American Transplant Congress
Real-Time Expert Evaluation of Liver Biopsy for Transplant: The Significance of Smartphone and Microscope Adapter in Telepathology
N. Bath,¹ X. Wang,² J. Bledsoe,² M. Thijssen,¹ A. Ahearn,¹ B. Movahedi,¹ A. Bozorgzadeh,¹ P. Martins.¹
¹Surgery, University of Massachusetts, Worcester, MA; ²Pathology, University of Massachusetts, Worcester, MA.
Introduction: Liver biopsy at the time of procurement plays a crucial role in the acceptance of marginal grafts. Local pathologists and transplant surgery fellows are…
2018 American Transplant Congress
Liver Biopsy Fibrosis Not Liver Imaging Predicts Survival after Heart Transplant
J. Patel, M. Kittleson, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles.
Purpose: Hepatic dysfunction is common in patients with cardiomyopathy being evaluated for heart transplant (HT). ISHLT guidelines highlight the need for liver evaluation in patients…
2018 American Transplant Congress
Evaluation of Transplant Kidneys Using a Novel Point of Care 3D Ultrasound System
J. Salinaro,¹ J. Broder,¹ E. Jaffa,¹ M. Morgan,¹ D. Vikraman-Sushama,¹ J. Dahl,² C. Herickhoff,² A. Limkakeng,¹ E. Peethumnongsin,¹ J. Borawski.¹
¹Duke University, Durham, NC; ²Stanford University, Palo Alto, CA.
Purpose: The clinical utility of two-dimensional (2D) ultrasound (US) in the evaluation of renal transplant patients is limited by user dependence and restricted planar image…
2018 American Transplant Congress
Assessing Fibrosis Burden in Renal Allograft with Chronic Damage Using Functional Magnetic Resonance Imaging
J. Wen,¹ W. Wang,² X. Ni,¹ Y. Yu,³ J. Chen,¹ L. Zhang,³ Z. Liu.¹
¹Jinling Hospital, Nanjing University School of Medicine, National Clinical Research Center of Kidney Diseases, Nanjing, Jiangsu, China; ²Nanjing Medical University, Jinling Clinical Hospital, Nanjing, Jiangsu, China; ³Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China.
Background: Renal allograft fibrosis burden is a strong prognosticator for chronic damage and can only be accurately measured through transplant biopsy at present. We hypothesized…
2018 American Transplant Congress
Noninvasive Quantization of Intra-Renal Allograft C4d Deposition with Targeted Ultrasound Imaging
T. Liao,¹ Y. Zhang,¹ J. Ren,² H. Zheng,¹ H. Zhang,² X. Liu,¹ T. Yin,² Q. Sun.¹
¹Organ Transplantation Research Institute, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Medical Ultrasound, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Antibody-mediated rejection (AMR) has emerged as the major cause of renal allograft dysfunction. C4d, a specific marker of AMR diagnosis, was strongly recommended for routine…
2017 American Transplant Congress
Testing the Efficacy of Contrast Enhanced Ultrasound in Detecting Transplant Rejection Using a Murine Model of Heart Transplantation.
K. Fisher,¹ M. Uehara,² S. Ohori,² C. Meral,¹ S. Giannini,³ T. Ichimura,² N. Smith,⁴ F. Jolesz,¹ I. Guleria,² Y. Zhang,¹ P. White,¹ N. McDannold,¹ K. Hoffmeister,³ M. Givertz,⁵ R. Abdi.²
¹Department of Radiology, Focused Ultrasound Laboratory, Brigham and Women's Hospital/ Harvard Medical School, Boston; ²Transplantation Research Center/Renal Devision, Brigham and Women's Hospital/ Harvard Medical School, Boston; ³Hematology Division, Department of Medicine, Brigham and Women's Hospital/ Harvard Medical School, Boston; ⁴Department of Pathology, Massachusetts General Hospital/ Harvard Medical University, Boston; ⁵Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital/ Harvard Medical School, Boston
One of the key unmet needs to improve long-term outcomes of heart transplantation is to develop accurate, non-invasive and practical diagnostic tools to detect transplant…
2017 American Transplant Congress
Predictive Value of Renal Transplant Scintigraphy for the Duration of Delayed Graft Function.
S. Benjamens,^1,2 R. Pol,¹ A. Glaudemans,² S. Berger,³ R. Slart.²
¹Surgery - Transplantation, University Medical Center Groningen, Groningen, Netherlands; ²Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, Netherlands; ³Internal Medicine - Division of Nephrology, University Medical Center Groningen, Groningen, Netherlands
Background: Renal scintigraphy (RS) is a widely used test for the assessment of the transplanted kidney (KTX). As RS cannot reliably distinguish between rejection and…
2017 American Transplant Congress
Imaging Cell Biology in Transplantation.
T. Ueno,¹ M. McGrath,¹ M. Yeung,¹ K. Jung,² Y. Kihara,³ O. Konno,³ Y. Nakamura,³ H. Iwamoto,³ S. Yun,² A. Chandraker.¹
¹Transplantation Research Center, Brighma and Women's Hospital, Harvard Medical School, Boston, MA; ²Department of Dermatology, Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; ³Transplantation Surgery, Tokyo Medical University, Hachioji, Tokyo, Japan
Background: Following transplantation, a set of coordinated events occurs within the recipient immune system. Immature dendritic cells (DCs) migrate to sites of inflammation, become activated…
2017 American Transplant Congress
Myocardial Improvement Six Months After Kidney Transplantation: Non-Contrast Cardiac Resonance Study.
M. Contti, L. Morales-Buenrostro, H. Nga, P. Garcia, M. Barbosa, H. Takase, M. da Silva, A. Moyses.
Internal Medicine, Botucatu School of Medicine, Botucatu, Sao Paulo, Brazil
INTRODUCTION: Patients with stage 5 chronic kidney disease (CKD) are at increased risk of cardiovascular disease, considering left ventricular hypertrophy (LVH) an independent risk for…
2016 American Transplant Congress
Imaging Cell Biology In Vivo with Intravital-Microscopy.
T. Ueno,¹ M. Yeung,¹ N. Igarashi,³ T. Yokoyama,² Y. Kihara,² O. Konno,² Y. Nakamura,² H. Iwamoto,² T. Ikeda,³ M. McGrath,¹ M. Sayegh,¹ A. Chandraker.¹
¹Renal Division, Transplantation Research Center, Brigham and Women's Hospital, Boston, MA; ²Transplant Surgery, Tokyo Medical Univ., Hachioji, Tokyo, Japan; ³Intensive Care Medicine, Tokyo Medical Univ., Hachioji, Tokyo, Japan.
Background: Despite current immunosuppressive therapy, many recipients endure multiple episodes of acute rejection. The interplay between dendritic cells (DCs) and T cells plays a central…