ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "HLA matching"

  • 2022 American Transplant Congress

    Allo-Sensitization is Increased in Liver Transplant Recipients Following Ischemia-Reperfusion Injury

    R. A. Sosa, A. Q. Terry, Y. Yin, B. V. Naini, F. M. Kaldas, R. W. Busuttil, D. W. Gjertson, J. W. Kupiec-Weglinski, E. F. Reed

    UCLA, Los Angeles, CA

    *Purpose: Recipient sensitization to donor HLA antigens remains an important clinical problem in transplantation, leading to increased wait times to find a compatible donor and…
  • 2022 American Transplant Congress

    Concurrent Use of Two Methods Prevents Erroneous HLA Typing of Deceased Organ Donors – An Essential Strategy for Patient Safety and Accurate Virtual Crossmatching for Broader Sharing

    R. Rajalingam, T. dela Cruz, C. Dames, L. Pagaduan, Y. Cho, D. Kong

    Immunogenetics and Transplantation Laboratory (ITL), University of California San Francisco, San Francisco, CA

    *Purpose: Comprehensive and accurate typing for ever-increasing alleles of all eleven HLA genes within a short turnaround time is a crucial initial step for allocating…
  • 2022 American Transplant Congress

    Performance of Kidney Transplantation in a Resource-Poor Setting of Southeast Nigeria- A Review of the First Ten Cases

    C. G. Okwuonu1, O. J. Chimezie2, G. O. Achor3, N. M. Erondu4, C. Ralph-Iheke5, S. Alhassan6

    1INTERNAL MEDICINE/NEPHROLOGY, Federal Medical Centre, Umuahia, Nigeria, 2OPTOMETRY, Federal Medical Centre, Umuahia, Nigeria, 3SURGERY/UROLOGY, Federal Medical Centre, Umuahia, Nigeria, 4ANAESTHESIA, Federal Medical Centre, Umuahia, Nigeria, 5NURSING SERVICES DIVISION, Federal Medical Centre, Umuahia, Nigeria, 6SURGERY/UROLOGY, Aminu Kano Teaching Hospital, Kano, Nigeria

    *Purpose: To assess complication and survival after performance of kidney transplantation in a resource poor setting in Southeast Nigeria*Methods: A retrospective review of transplant registers…
  • 2022 American Transplant Congress

    HLA DSA May Not Be Detected in Many Solid Organ Recipients

    J. C. Quon1, R. M. Lestz2, J. Menteer2, N. Fotiadis2, L. A. Baxter-Lowe2

    1Keck School of Medicine, Los Angeles, CA, 2Children's Hospital Los Angeles, Los Angeles, CA

    *Purpose: Clinically significant HLA antibodies may not be detected if their unique HLA epitopes are not represented in the single antigen reagents that are routinely…
  • 2022 American Transplant Congress

    A Novel Application of SRTR Data to Interrogate the Effects of HLA-DQ Mismatches in Kidney Transplantation

    D. Isaacson1, M. W. Gmeiner2, V. Kosmoliaptsis3, H. C. Copley3, J. D. Schold4, A. R. Tambur1

    1Northwestern University, Chicago, IL, 2London School of Economics, London, United Kingdom, 3Cambridge University, Cambridge, United Kingdom, 4Cleveland Clinic, Cleveland, OH

    *Purpose: Single-center studies demonstrate de-novo HLA-DQ donor-specific antibodies (DSA) are the most common and pathogenic DSA. However, HLA-DQ is not accounted for in many kidney…
  • 2021 American Transplant Congress

    Clinical Outcomes and Racial Impact of HLA Matching in the Australian Deceased Donor Kidney Transplantation Program, 2000-2018

    M. Gramlick, M. Heer

    Department of Surgery, John Hunter Hospital, Newcastle, Australia

    *Purpose: The Australian deceased donor (DD) kidney transplant program places a large emphasis on HLA matching despite a known disadvantage to ethnic minority groups. We…
  • 2021 American Transplant Congress

    An HLA Class II Matching Strategy That Predicts De Novo Donor-specific HLA Antibody Formation Using Low Resolution HLA Types

    L. Hidalgo1, I. Martinez Juarez2, L. Morales Buenrostro2, S. Shojai3, P. Campbell1

    1University of Wisconsin Madison, Madison, WI, 2Instituto Nacional de Ciencias Medicas Y Nutricion Salvador Zubrian, Mexico City, Mexico, 3Medicine, University of Alberta, Edmonton, AB, Canada

    *Purpose: The development of de novo donor-specific HLA antibodies (dnDSA) is predominantly against HLA-Class II antigens and is a function of the degree of HLA-DQ…
  • 2021 American Transplant Congress

    Towards National Organ Sharing: Fair Distribution of Eplets in Canada

    S. Parto, B. Liu, W. Klement, S. Oikonomopoulos, I. Ragoussis, R. Sapir-Pichhadze

    McGill University, Montreal, QC, Canada

    *Purpose: Eplet matching is being promoted as a rational approach to prevent immune-mediated injuries in transplantation. We studied the frequencies of eplets in a Canadian…
  • 2021 American Transplant Congress

    Risk Stratification of Kidney Transplant Patients According to the Different Level of HLA-DQ Disparities

    A. Senev1, A. R. Tambur2, M. Naesens1

    1Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 2Northwestern University, Chicago, IL

    *Purpose: It is becoming clear that de novo donor-specific antibodies (dnDSA) against HLA-DQ are the most prevalent and the leading cause of chronic antibody-mediated rejection…
  • 2021 American Transplant Congress

    Influence of HLA Compatibility on Bk Virus Associated Nephropathy Among Japanese Living Donor Kidney Transplant Recipients

    N. Fujiyama1, M. Saito2, R. Yamamoto2, R. Sagehashi2, T. Saito2, S. Kashima2, K. Numakura2, S. Narita2, T. Habuchi2, S. Satoh1

    1Center for Kidney Disease and Transplantaion, Akita University Hospital, Akita, Japan, 2Department of Urology, Akita University Graduate School of Medicine, Akita, Japan

    *Purpose: BK polyomavirus-associated nephropathy (BKVN) after kidney transplantation is associated with a high morbidity and higher risk of graft loss. In this study, the relationship…
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