2022 American Transplant Congress
Improving Value Delivery in Compatible Living Donor Kidney (CLD) Transplant Through Zero-Low Eplet Mismatch via National Kidney Registry (NKR)
1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA
*Purpose: Despite advances in diagnostics and therapeutics, kidney allograft survival rates have not increased considerably. Kidney For Life (KFL) through NKR aims to increase access…2022 American Transplant Congress
Does Black Race Modify the Risk of Transplant Failure Associated with HLA Mismatch in First Adult Kidney Allografts from Deceased Donors?
Tulane University, New Orleans, LA
*Purpose: Current US- based data suggests Black patients awaiting kidney re-transplantation are more likely to be highly sensitized compared to other races. Degree of HLA…2022 American Transplant Congress
HLA-DQ Mismatches Are More Likely to Be Listed as Unacceptable Antigens After Renal Graft Failure in African American Recipients as Compared to Other Racial/Ethnic Groups
*Purpose: Growing evidence suggests that donor-recipient mismatches at the HLA-DQ locus are the most immunogenic and pathogenic, evidenced by generation of DQ donor-specific antibodies (DSA).…2022 American Transplant Congress
Impact of HLA Matching on Graft Survival in Kidney Transplant Recipients
*Purpose: This study aims to estimate the association of HLA matching at the A, B, DR, and DQ loci with posttransplant graft failure and patient…2022 American Transplant Congress
Allo-Sensitization is Increased in Liver Transplant Recipients Following Ischemia-Reperfusion Injury
*Purpose: Recipient sensitization to donor HLA antigens remains an important clinical problem in transplantation, leading to increased wait times to find a compatible donor and…2021 American Transplant Congress
Clinical Outcomes and Racial Impact of HLA Matching in the Australian Deceased Donor Kidney Transplantation Program, 2000-2018
Department of Surgery, John Hunter Hospital, Newcastle, Australia
*Purpose: The Australian deceased donor (DD) kidney transplant program places a large emphasis on HLA matching despite a known disadvantage to ethnic minority groups. We…2021 American Transplant Congress
An HLA Class II Matching Strategy That Predicts De Novo Donor-specific HLA Antibody Formation Using Low Resolution HLA Types
*Purpose: The development of de novo donor-specific HLA antibodies (dnDSA) is predominantly against HLA-Class II antigens and is a function of the degree of HLA-DQ…2021 American Transplant Congress
Towards National Organ Sharing: Fair Distribution of Eplets in Canada
McGill University, Montreal, QC, Canada
*Purpose: Eplet matching is being promoted as a rational approach to prevent immune-mediated injuries in transplantation. We studied the frequencies of eplets in a Canadian…2021 American Transplant Congress
Risk Stratification of Kidney Transplant Patients According to the Different Level of HLA-DQ Disparities
*Purpose: It is becoming clear that de novo donor-specific antibodies (dnDSA) against HLA-DQ are the most prevalent and the leading cause of chronic antibody-mediated rejection…2021 American Transplant Congress
Influence of HLA Compatibility on Bk Virus Associated Nephropathy Among Japanese Living Donor Kidney Transplant Recipients
*Purpose: BK polyomavirus-associated nephropathy (BKVN) after kidney transplantation is associated with a high morbidity and higher risk of graft loss. In this study, the relationship…
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