2016 American Transplant Congress
Improving Kidney Allocation System with Higher Resolution.
Northwestern University, Chicago, IL.
Purpose: The new kidney allocation system (KAS) was implemented to help identify compatible donors for the most highly sensitized patients. Our experience, as well as…2016 American Transplant Congress
Graft Survival in Sensitized and Non-Sensitized Patients: Role of the Combination of Donor-Specific Antibodies and Acute Rejection.
Background: Sensitized (S) patients have higher risk for acute rejection (AR), especially ABMR. DSA is a risk fator for ABMR, however, its impact on AR…2016 American Transplant Congress
Solid Phase Assay Demonstrates High Rates of Allosensitization in Pediatric Heart Recipients.
Allosensitization is a risk factor for rejection, vasculopathy and graft loss. CTOTC-04 is a prospective study assessing the impact of sensitization on a composite of…2015 American Transplant Congress
Assessment of IgG Subclass Significance for Early Graft Rejection and Long-Term Survival in HLA-Antibody Incompatible Renal Transplantation: Multivariate Approach
Donor HLA specific antibodies (DSA) can cause acute rejection and graft lost after renal transplantation. However neither the damaging antibody types, nor their acceptable levels…2015 American Transplant Congress
Antibodies Directed Against HLA-DQ Are Significantly Associated to Complement Activation In Vitro
Background: C1q-binding HLA antibodies (HLAabs) have been related to acute rejection and long-term graft loss. The characteristics of these antibodies and factors associated to complement…2015 American Transplant Congress
Post-Kidney Allograft Nephrectomy Anti-HLA Immunization Is Not Due to a Release of Anti-HLA Antibodies from the Failed Kidney
Background and aims: The reasons for the increased incidence of de novo anti-HLA donor specific antibodies (DSAs) that is observed after kidney allograft nephrectomy (NTx)…2015 American Transplant Congress
Intermittent High Dose Intravenous Immunoglobulin as Treatment for Donor Specific Antibodies in Renal Transplant Recipients
Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population have indicated…2015 American Transplant Congress
Prediction of Acute Antibody Mediated Rejection in Antibody Incompatible Renal Transplantation Using Machine Learning for Wide Data
The dynamic field of renal transplantation is characterised by limited access to data, the high cost of equipment and underlying complexity of immunological responses to…2015 American Transplant Congress
Retrospective Cohort Study Concerning Efficacy and Safety of Bortezomib in Combination With Or Without Rituximab in Antibody Mediated Rejection in Renal Transplant Recipients
Charité Universitätsmedizin Berlin, Department of Nephrology, Berlin, Germany.
Treatment of antibody-mediated rejection (AMR) in renal transplant (tx) patients (pts) is still challenging and long-term outcome remains unsatisfying. Because plasma cells (PCs) are crucial…2015 American Transplant Congress
Husband to Wife Renal Transplants Are Associated With a Higher Risk of Early Antibody Mediated Rejection and Transplant Glomerulopathy
Patients with a low level preformed donor specific antibodies [DSA] with a negative FCXM/CDC cross match are at high risk of antibody mediated rejection [AMR]…
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