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Articles tagged "HIV virus"

  • 2015 American Transplant Congress

    Changing Demographics of HIV+ Liver Transplant Candidates

    C. Durand, S. Gustafson, J. Locke, J. Snyder, B. Shelton, R. Reed, P. MacLennan, S. Mehta, A. Nellore, D. Segev.

    Johns Hopkins University, Baltimore, MD; Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; University of Alabama, Birmingham, Birmingham, AL.

    Liver transplant (LT) is considered a reasonable therapeutic option for certain HIV+ patients with end-stage liver disease (ESLD). As OPTN does not collect HIV status…
  • 2015 American Transplant Congress

    Defining the Epidemiologic Landscape of HIV-Infected Deceased Donors in the United States

    A. Cash, A. Shaffer, S. Anjum, A. Massie, D. Segev, C. Durand.

    Surgery, Johns Hopkins University, Baltimore, MD.

    The HIV Organ Policy Equity Act mandates research on the use of HIV-infected (HIV+) deceased donors (HIVDD) for transplantation in HIV+ recipients. The only data…
  • 2015 American Transplant Congress

    Induction With ATG Is Not Associated With Increased Infections After Kidney Transplant Among HIV Positive Patients: Results of a National Study

    L. Kucirka,1 C. Durand,1 S. Bae,1 J. Locke,2 D. Segev.1

    1JHU, Baltimore; 2UAB, Birmingham.

    Anti-thymocyte globulin (ATG) is widely used for induction, particularly for those at high risk for rejection. HIV+ kidney transplant (KT) recipients have 3 fold higher…
  • 2015 American Transplant Congress

    Outcomes of HIV+ Liver Transplant Recipients Compared to HCV+ or HIV+/HCV+ Co-Infected Recipients: The “Real World” Experience

    D. Sawinski,1 G. David,2 E. Blumberg,3 P. Abt,4 R. Bloom,1 K. Forde.2

    1Renal Division, Univ. of Penn, Philadelphia, PA; 2Gastroenterology Division, Univ. of Penn, Philadelphia, PA; 3Infectious Disease, Univ. of Penn, Philadelphia, PA; 4Surgery, Univ of Penn, Philadelphia, PA.

    End stage liver disease is a frequent cause of mortality in patients with HIV. Though demonstrated in the NIH observational trial, the effectiveness of LT…
  • 2015 American Transplant Congress

    Impact of Induction Therapy on Outcomes in HIV + Renal Transplant Recipients

    C. Kershaw,1 C. Rogers,2,4 M. Pavlakis,1,2 H. Tang,2 C. Alonso,1,2 K. Khwaja,2,3 A. Evenson,2,3 K. Raven,2,3 M. Wong.1,2

    1Medicine, Beth Israel Deaconess Medical Center (BIDMC), Boston, MA; 2The Transplant Institute, BIDMC, Boston, MA; 3Surgery, BIDMC, Boston, MA; 4Pharmacy, BIDMC, Boston, MA.

    Purpose: Kidney transplantation in HIV+ recipients has been complicated by higher than expected acute rejection rates (AR). Induction immunosuppression may or may not impact this…
  • 2015 American Transplant Congress

    Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates

    J. Locke,1 S. Gustafson,2 C. Durand,3 J. Snyder,2 B. Shelton,1 R. Reed,1 P. MacLennan,1 S. Mehta,1 A. Nellore,1 D. Segev.2,3

    1University of Alabama, Birmingham, AL; 2Scientific Registry of Transplant Recipients (SRTR), Minneapolis Medical Research Foundation, Minneapolis, MN; 3Johns Hopkins University, Baltimore, MD.

    Chronic diseases, such as end-stage renal disease (ESRD), are now the leading causes of death among HIV+ patients. Multiple studies have demonstrated the efficacy of…
  • 2015 American Transplant Congress

    Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients

    J. Locke,1 R. Reed,1 S. Mehta,1 C. Durand,2 R. Mannon,1 P. MacLennan,1 B. Shelton,1 M. Martin,1 H. Qu,1 R. Shewchuk,1 D. Segev.2

    1Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham; 2Comprehensive Transplant Center, Johns Hopkins Medical Institutions, Baltimore.

    Background: Excellent outcomes among HIV+ kidney transplant (KT) recipients have been reported by the NIH consortium, but it is unclear if experience with HIV+ KT…
  • 2015 American Transplant Congress

    Impact of Integrase Inhibitor-Based Antiretroviral Regimen on Outcomes in HIV + Renal Transplant Recipients

    C. Kershaw, C. Rogers, M. Pavlakis, H. Tang, C. Alonso, K. Khwaja, A. Evenson, K. Raven, M. Wong.

    Beth Israel Deaconess Medical Center, Boston.

    Renal transplant in HIV+ patients (pts) is complicated by high rates of acute rejection (AR). Protease inhibitors (PIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs) have…
  • 2015 American Transplant Congress

    Similar Outcomes Can Be Expected Among HIV (+) Kidney Transplant Recipients (HIV+ Tx) Vs. HIV (-) Kidney Transplant Recipients (HIV- Tx) Receiving Similar Immunosuppression Protocols

    L. Panarey,1 G. Malat,2,3 A. Sharma,1 K. Ranganna,1 D. Reich,2 G. Xiao,2 A. Doyle.1

    1Dept of Medicine, Drexel University College of Medicine, Philadelphia; 2Dept of Surgery, Drexel University College of Medicine, Philadelphia; 3Dept of Pharmacy, Hahnemann University Hospital, Philadelphia, PA.

    Outcomes among HIV+ Tx continue to improve despite the established risk of rejection and calcineurin-nephrotoxicity. We sought to compare outcomes among HIV+ Tx vs. HIV-…
  • 2015 American Transplant Congress

    Characteristics of HIV Infected Patients Waitlisted for Kidney Transplantation

    N. Law,1 A. Doyle,1 A. Sharma,1 G. Malat,2 T. Bias,1 K. Ranganna,1 D. Lee.1

    1Department of Medicine, Drexel University, College of Medicine, Philadelphia, PA; 2Department of Surgery, Drexel University, College of Medicine, Philadelphia, PA.

    IntroductionKidney transplantation in HIV+ individuals has been associated with patient and graft survival rates that are comparable to those reported for HIV- populations. Despite this…
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