2019 American Transplant Congress
Role of Kidney Biopsy in Simultaneous Heart-Kidney Transplantation
*Purpose: Simultaneous heart-kidney (SHK) transplantation has superior post-transplant survival compared to heart transplantation alone in end-stage heart failure patients who have dialysis dependent or non-dialysis…2019 American Transplant Congress
Reduction of Circulating DSA: Does It Affect Histology?
*Purpose: De novo donor specific antibodies (dnDSA) are reported in 13-30% of kidney transplant recipients. dnDSA has been associated with antibody mediated rejection (AMR) and…2019 American Transplant Congress
Kidney Biopsies In Hiv-negative To Hiv-positive Kidney Transplants – An Institutional Experience
*Purpose: Increased life expectancy in HIV+ patients has resulted in an increase in CKD leading to ESRD; and therefore renal transplantation in these individuals is…2019 American Transplant Congress
Living Kidney Donor Time Zero Biopsy Findings Predict Graft Loss in the Recipient
*Purpose: Recipient outcomes with living donor kidney grafts are superior to those achieved from deceased donors. However, there may still be variability in the quality…2019 American Transplant Congress
Prevention of Diabetic Nephropathy after Kidney Transplantation Requires More Than Pursuing Low Levels of Glycated Hemoglobin
*Purpose: Diabetic nephropathy is the leading cause of end-stage renal disease and progresses in five stages. During the second stage, morphologic lesions develop, without signs…2019 American Transplant Congress
Correlation between Gene Expression and Histology in Transbronchial Lung Transplant Biopsies
University of Alberta, Edmonton, AB, Canada
*Purpose: Transbronchial lung transplant biopsies (TBBx) are limited by non-specific histologic lesions and suboptimal interobserver reproducibility. Gene expression offers a potentially more precise, objective and…2019 American Transplant Congress
Cluster Analysis of Microvascular Inflammation in Indication Biopsies Unveils Distinct Pathological and Immunological Phenotypes with Prognostic Implications
1Centro Hospitalar do Porto, Porto, Portugal, 2IPST_Porto, Porto, Portugal
*Purpose: We aimed to define distinct pathological and immunological clusters of 80 cases of MVI diagnosed in indication biopsies and evaluate their prognostic implications.*Methods: The…2019 American Transplant Congress
Clostridium difficile Infection Mimics Intestinal Acute Cellular Rejection in Pediatric Multivisceral Transplant – A Case Series
*Purpose: Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. One out of 8 recipients who undergo transplantation with more…2019 American Transplant Congress
Eculizumab Deposition in Renal Transplants
*Purpose: Eculizumab is a recombinant humanized IgG monoclonal antibody that inhibits C5, thereby preventing the activation of C5a and formation of membrane attack complex C5b-C9.…2019 American Transplant Congress
Kinetics of Pretransplant DSA, Post-Transplant Histology, and Graft Failure after Kidney Transplantation
*Purpose: The association between the kinetics of pretransplant DSA levels and outcome after kidney transplantation is currently not well known. In this large cohort study…
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