2019 American Transplant Congress
Patterns of Rejection in Murine, Porcine, and Human Vascularized Composite Allografts Based on Clinical, Histologic, and Immunohistochemical Analysis
Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: The side effects of chronic immunossupression limit the more extensive use of Vascularized Composite Allotransplantation (VCA), and because reliable pre-clinical animal models will be…2019 American Transplant Congress
Immunomics of Renal Allograft Acute T-Cell Mediated Rejection Biopsies of Tacrolimus- and Belatacept- Treated Patients
*Purpose: Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor based therapy, however…2019 American Transplant Congress
Clinical Response to Pathological Finding in Uterus Transplantation
Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Uterus transplantation has recently proven to be the first successful treatment for absolute uterine factor infertility with demonstration of live births. All reported episodes…2019 American Transplant Congress
First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic
*Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…2019 American Transplant Congress
Role of Kidney Biopsy in Simultaneous Heart-Kidney Transplantation
*Purpose: Simultaneous heart-kidney (SHK) transplantation has superior post-transplant survival compared to heart transplantation alone in end-stage heart failure patients who have dialysis dependent or non-dialysis…2019 American Transplant Congress
Reduction of Circulating DSA: Does It Affect Histology?
*Purpose: De novo donor specific antibodies (dnDSA) are reported in 13-30% of kidney transplant recipients. dnDSA has been associated with antibody mediated rejection (AMR) and…2019 American Transplant Congress
Kidney Biopsies In Hiv-negative To Hiv-positive Kidney Transplants – An Institutional Experience
*Purpose: Increased life expectancy in HIV+ patients has resulted in an increase in CKD leading to ESRD; and therefore renal transplantation in these individuals is…2019 American Transplant Congress
Living Kidney Donor Time Zero Biopsy Findings Predict Graft Loss in the Recipient
*Purpose: Recipient outcomes with living donor kidney grafts are superior to those achieved from deceased donors. However, there may still be variability in the quality…2019 American Transplant Congress
Prevention of Diabetic Nephropathy after Kidney Transplantation Requires More Than Pursuing Low Levels of Glycated Hemoglobin
*Purpose: Diabetic nephropathy is the leading cause of end-stage renal disease and progresses in five stages. During the second stage, morphologic lesions develop, without signs…2019 American Transplant Congress
Correlation between Gene Expression and Histology in Transbronchial Lung Transplant Biopsies
University of Alberta, Edmonton, AB, Canada
*Purpose: Transbronchial lung transplant biopsies (TBBx) are limited by non-specific histologic lesions and suboptimal interobserver reproducibility. Gene expression offers a potentially more precise, objective and…
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