ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Histocompatibility antigens"

  • 2015 American Transplant Congress

    HLA-Cw Mismatches Are Not Associated With Worse Graft Outcomes After Kidney Transplantation Even in High Levels of Antigen Expression

    M. Askar,1 N. Elfadawy,1,2 S. Flechner,1 K. Abu-Elmagd,1 J. Fung,1 J. Schold.1

    1Cleveland Clinic, Cleveland; 2University of Alexandria, Alexandria, Egypt.

    The HLA-Cw antigens are distinct in having relatively lower expression on the cell surface compared to the other HLA class I loci. Higher HLA Cw…
  • 2015 American Transplant Congress

    Reasons for Match Offer Refusals and Efforts to Reduce Them in the OPTN/UNOS Kidney Paired Donation Pilot Program (KPDPP)

    R. Leishman,1 D. Stewart,1 A. Kucheryavaya,1 L. Robbins Callahan,1 T. Sandholm,2 M. Aeder.3

    1UNOS, Richmond, VA; 2Carnegie Mellon Univ, Pittsburgh, PA; 3Univ Hosp Case Med Ctr, Cleveland, OH.

    Background: The OPTN/UNOS KPDPP has been finding 2-way, 3-way, and chain exchanges since Oct 2010. Though the number of pairs entered, matches found, and transplants…
  • 2015 American Transplant Congress

    Antibodies Directed Against HLA-DQ Are Significantly Associated to Complement Activation In Vitro

    J. Arreola-Guerra, A. de Santiago, A. Arvizu, N. Gonzalez-Tableros, M. Lopez, M. Vilatoba, L. Morales-Buenrostro, J. Alberu, N. Castelan.

    1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Distrito Federal, Mexico.

    Background: C1q-binding HLA antibodies (HLAabs) have been related to acute rejection and long-term graft loss. The characteristics of these antibodies and factors associated to complement…
  • 2015 American Transplant Congress

    Accurate Prediction of High-Resolution HLA-A, -B, -C, -DRB1 and -DQB1 Typing and Low-Resolution HLA-DQA1 Typing by Haplotype Analysis

    A. Jaramillo,1 R. Vaidya,2 M. Pando,3 S. Gaitonde.4

    1Histocompatibility & Immunogenetics Laboratory, Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 2College of Pharmacy, Roseman University of Health Sciences, South Jordan, UT; 3Department of Laboratory Medicine & Pathology, Mayo Clinic, Phoenix, AZ; 4Department of Pathology, University of Illinois, Chicago, IL.

    Aim: Allele-specific HLA antibodies are commonly detected by Luminex single antigen bead assays in solid organ transplant recipients. However, high-resolution HLA typing for deceased donors…
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