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Articles tagged "Hepatitis C"

  • 2015 American Transplant Congress

    The Benefit of Hepatitis C Donor Kidney Transplantation Is Limited to Hepatitis C Positive Patients Over 50 Years of Age

    T. Myint, A. Wright, C. Rose, C. Kennedy, J. Dong, J. Gill, J. Gill.

    Division of Nephrology, University of British Columbia, Vancouver, BC, Canada.

    The purpose of this analysis was to provide information regarding the use and survival benefit of kidney transplantation from a hepatitis C positive deceased donor…
  • 2015 American Transplant Congress

    Long-term Patient and Graft Survival After Kidney Transplantation in Recipients With Hepatitis C Virus Infection

    N.-Y. Heo, P. Udompap, A. Mannalithara, W. Kim.

    Division of Gastroenterology and Hepatology, Stanford University, Stanford.

    Background: The prevalence of hepatitis C virus (HCV) infection among kidney transplant (KTx) recipients is higher than that in the general population. With the advent…
  • 2015 American Transplant Congress

    Combined Hepatitic/Cholangiopathic Lesion in HIV-HCV Co-Infected Liver Transplant Recipients Associated With Graft Loss

    J. Harbell,1 A. Doherty,2 L. Ferrell,2 B. Barin,3 N. Terrault,1 P. Stock.1

    1Surgery, University of California, San Francisco, San Francisco, CA; 2Pathology, University of California, San Francisco, San Francisco, CA; 3EMMES Corporation, Rockville, MD.

    Background: Co-infection with HIV and viral hepatitis results in poorer outcomes following liver transplantation. In this population, complex immune status, extensive drug regimens, and comorbid…
  • 2015 American Transplant Congress

    Interferon-Free Sofosvir/Ribavirin Treatment Achieves Excellent Sustained Viral Response in Post Liver Transplant HCV Recipients

    M. Hamshow, K. Bortecen, R. Layman, A. Winnick, B. Gelb, G. Morgan, L. Teperman.

    Transplant Surgery, NYU Langone Medical Center,The Mary Lea Johnson Richards Organ Transplant Center, New York, NY.

    Purpose: HCV is the leading cause of end-stage liver disease, universally recurring in the post-transplant setting. Studies have shown disappointing results after first generation protease…
  • 2015 American Transplant Congress

    HCV Treatment in Liver Transplantation: Changes in Center Attitudes and Practices in the DAA Era

    A. Shaffer, A. Cash, S. Anjum, D. Segev, C. Durand.

    Surgery, Johns Hopkins University, Baltimore, MD.

    Chronic hepatitis C virus infection (HCV) is the leading indication for liver transplantation (LT) in the US. Safe and effective directly acting antivirals (DAAs) are…
  • 2015 American Transplant Congress

    Efficacy of Sofosbuvir Based Therapy for Recurrent Hepatitis C After Liver Transplantation

    A. Weick,1 K. George,1 S.-M. Jafri,2 D. Moonka.2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI; 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI.

    Purpose: Evaluate outcomes of sofosbuvir-based hepatitis C therapy in liver transplant patients in a single center clinical setting, including interferon-free regimens.Methods: All patients with history…
  • 2015 American Transplant Congress

    Outcomes of Hepatitis C Virus (HCV) Treatment Following Liver Transplantation in the Era of Direct-Acting Antiviral Medications

    S. Baggett,1 D. Jones,1 M. Shoreibah.2

    1Department of Pharmacy, UAB Hospital, Birmingham, AL; 2Department of Gastroenterology, UAB Hospital, Birmingham, AL.

    BACKGROUND: The treatment of HCV is one of the most rapidly changing areas of medical practice. These agents have been shown to be safe and…
  • 2015 American Transplant Congress

    High Tolerability With Sofosbuvir-Based Direct-Acting Antiviral Therapy in Liver Transplant Recipients With Recurrent Hepatitis C

    B. Osborne,1 A. Modi,1 M. Gautam,1 N. Murray,1 I. Gonzalez,2 J. McAfee,2 S. Gonzalez.1

    1Hepatology, Baylor Simmons Transplant Institute, Fort Worth, TX; 2Hepatology, Liver Consultants of Texas, Fort Worth, TX.

    Background: Reports on efficacy, safety, and tolerability of sofobuvir-based antiviral regimens in liver transplant recipients with recurrent hepatitis C are limited. Methods: We performed a…
  • 2015 American Transplant Congress

    Long-Term Outcome of Liver Transplant Recipients (OLT) With Hepatitis C Recurrence (HCVR) Who Achieved Postoperative Sustained Virologic Response (SVR) After Combination Antiviral Therapy (Rx) With and Without the Use of Telaprevir (TVR): A Single Center Experience

    C. Fasola, P. Mantry, J. Weinstein, H. Nazario, A. Mubarak, M. Barnes, A. Habib, A. Mejia, R. Dickerman, S. Cheng.

    Liver Institute, Methodist Dallas Medical Center, Dallas, TX.

    Aim: Liver allografts of viremic OLT have a higher risk of failure. Timely intervention is necessary. However, long-term outcome reports, especially using newer agents, is…
  • 2015 American Transplant Congress

    Sofosbuvir-Based Therapy for Hepatitis C Recurrence Post Liver Transplantation

    A. Ajlan,1 A. Aljedai,1 H. Elsiesy,2 D. Alkortas,1 R. Alarieh,2 F. Aba Alkhail.2

    1Pharmaceutical Care Division, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia; 2Liver And Small Bowel Trans and Hep/Pancreatic Surgey -Organ Transplant Centre (OTC), King Faisal Specialist Hospital and Research Centre, Riaydh, Saudi Arabia.

    Introduction:Sofosbuvir is approved to treat HCV infection in all genotypes with sustained virological response 12 weeks after completion of therapy (SVR12)rates of up to 100%.…
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