2020 American Transplant Congress
Use of Letermovir for Cytomegalovirus Management in Thoracic Organ Transplantation
Duke University Medical Center, Durham, NC
*Purpose: Cytomegalovirus (CMV) commonly affects thoracic solid organ transplant (SOT) recipients, and standard antiviral therapies are limited by myelosuppression, renal dysfunction, and emergence of resistance.…2020 American Transplant Congress
Affect in Patients Awaiting Heart Transplant
*Purpose: Affect refers to an individual’s emotional response .It may be categorized as positive or negative. Affect in heart transplant candidates is under-explored. We aimed…2020 American Transplant Congress
Uncovering Factors That Lead to an Increase in Significant Early Rejection Outcomes in Cardiac Transplant Patients
*Purpose: The factors that lead to an increase in significant early rejection (stage 2R or greater) along with the preferred induction immunosuppression strategy in orthotopic…2020 American Transplant Congress
Socio-Demographic Disparities in Access to Organs from HCV-Viremic Donors among HCV-Negative Patients
*Purpose: The success of pilot trials of transplanting organs from hepatitis C virus (HCV) viremic donors into HCV-negative recipients (HCV D+/R-) has led to an…2020 American Transplant Congress
Comparison of Six-Month Outcomes in Patients Bridged to Heart Transplantation with Percutaneous Temporary Circulatory Support Before and after the UNOS Allocation System Change
*Purpose: We report the trends in utilization and outcomes of percutaneous temporary circulatory support (TCS) in the forms of Impella or TandemHeart as a bridge…2020 American Transplant Congress
Is 3-4+ Liver Fibrosis a Contraindication to Heart Transplantation?
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Chronic liver disease in patients awaiting heart transplant is seen in patients with biventricular heart failure. This is mostly due to congestive hepatopathy due…2020 American Transplant Congress
Anti-Thymocyte Globulin Promotes Tfh Cells Differentiation and Alloantibody Production
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
*Purpose: Antibody-mediated rejection is a major cause of long-term graft loss. T follicular helper (Tfh) cell is CD4+ T cell subset that is specialized in…2020 American Transplant Congress
Foxp3+ Innate and TGF-ß+ Adaptive Regulatory Immune Cells in Quilty Lesions are Associated with Acceptance of Heart Allograft
University of Texas Southwestern Medical Center, Dallas, TX
*Purpose: To evaluate the cellular composition of Quilty lesions in heart transplant biopsies and their association with acceptance or rejection of cardiac allografts.*Methods: This study…2020 American Transplant Congress
Heart Transplant Outcomes for Patients with Left Ventricular Assist Devices (LVAD) Before and after the 2018 Revision of the United Network for Organ Sharing (UNOS) Adult Heart Allocation System
*Purpose: In October of 2018 UNOS chaged their adult heart allocation criteria to address disparity in waiting list survival. The implications of this policy change…2020 American Transplant Congress
Recipient Expression of C-Type Lectin Receptor Mincle Promotes Rapid T Cell Homeostatic Recovery Following Antibody Mediated Lymphoablation
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: Antibody-mediated lymphocyte depletion is widely used in transplantation. We recently established that T cell recovery in mouse heart allograft recipients treated with anti-thymocyte globulin…
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