2022 American Transplant Congress
Status Exception Use in the New Seven-Tiered Heart Allocation System
*Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
Fontan versus Non-Fontan Combined Heart-Liver Transplantation: Proceed but Cautiously
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Combined heart-liver transplantation (CHLT) is increasing, corresponding with a growing prevalence of Fontan-associated end-organ damage. We aimed to describe our contemporary institutional experience with…2022 American Transplant Congress
Cryptococcal Meningitis Presenting as SIADH in a Heart Transplant Recipient
Temple University Hospital, Philadelphia, PA
*Purpose: Cryptococcal meningitis is a potentially fatal invasive fungal infection in solid organ transplant recipients. Meningoencephalitis is the most common clinical manifestation of cryptococcal infection.…2022 American Transplant Congress
Real-Time Biometric Monitoring Using Wearable Devices for Pediatric Heart Transplant Rejection and Infection Surveillance
*Purpose: Monitoring for acute rejection (AR) after orthotopic heart transplantation (OHTx) is primarily achieved by evaluating histological endomyocardial biopsies (EMBx). However, this procedure is limited…2022 American Transplant Congress
Evaluation of Conversion from Immediate Release (IR) Tacrolimus to LCP-Tacrolimus (Envarsus XR®, LCP) in Heart Transplant Recipients
1University of Illinois at Chicago, Chicago, IL, 2Loyola University Medical Center, Maywood, IL
*Purpose: The purpose of this study was to assess outcomes in heart transplant recipients who were converted from IR tacrolimus to LCPT. Limited data exists…2022 American Transplant Congress
Donor Derived Cell-Free DNA Median and Distribution in Pediatric Heart Transplant Patients
1CareDx, South San Francisco, CA, 2Children's Hosp of Pittsburgh, Pittsburgh, PA
*Purpose: The utilization of endomyocardial biopsy (EMB) in the post-transplant surveillance of pediatric heart transplant (pHT) recipients can be challenging for a myriad of reasons;…2022 American Transplant Congress
Superoxide in Cardiac Allografts from Donors After Circulatory Death
*Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…2022 American Transplant Congress
Early Retrieval of the Right Kidney for Combined Heart and Kidney Transplantation is Feasible and Reduces Costs
*Purpose: Combined heart and kidney transplants (cHKT) have increased in recent years. Standard procurement practice often necessitates kidney extraction and packaging after the heart team…2022 American Transplant Congress
p40 Homodimers Stimulate Graft Dendritic Cells to Produce IL-15 Driving Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts
*Purpose: Acute allograft injury occurring during the first 1-2 days post-transplant is mediated by graft infiltrating endogenous donor-reactive memory CD8 T cells and requires their…
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