2020 American Transplant Congress
Novel Approaches in Targeting Chromatin Modifiers in the Induction of Transplant Tolerance
Houston Methodist Research Institute, Houston, TX
*Purpose: Bromodomain and extra-terminal domain (BET) proteins are a family of proteins that function as epigenetic readers that regulate transcriptional activities of target genes. BET…2020 American Transplant Congress
The Effect of UNOS Donor Policy Change on Ischemic Time and the Effects on Mortality in Heart Transplantation
*Purpose: In light of the recent change in the UNOS allocation policy, we sought to evaluate the impact of ischemic time on mortality.*Methods: Using the…2020 American Transplant Congress
Patient Attitudes Regarding Contraception and Pregnancy after Transplantation
*Purpose: Professional society recommendations regarding contraception and pregnancy after transplantation exist but little is known about patient attitudes.*Methods: We conducted a survey of female transplant…2020 American Transplant Congress
Do the Characteristics of Donor Specific Antibody Truly Predict Severity of Cardiac Allograft Vasculopathy Late after Transplantation?
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: The development of donor specific antibody (DSA) has been correlated to the development of cardiac allograft vasculopathy (CAV) after heart transplantation. However, it has…2020 American Transplant Congress
Exosomes Released from Natural Killer Cells Activation of Immune Responses: Role in Chronic Lung Allograft Dysfunction
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Recent studies demonstrated natural killer (NK) cells can induce cytotoxicity both by direct cytotoxic mechanisms and antibody (Ab) dependent cytotoxicity; however its role in…2020 American Transplant Congress
The Reperfusion Response in Plasma of Combined Heart/ Lung Transplanted Patients is Guided by Heart-Associated Cytokine Patterns on Contrast to the Ischemic Injury in Perfusion Solutions Following a Lung-Associated Pattern
*Purpose: Organ-specific differences are discussed for ischemia/reperfusion injury (IRI) in cardiothoracic transplantation but rarely compared directly in a clinical setting. Therefore, we compared a cohort…2020 American Transplant Congress
Gal9/Tim-3 Pathway was Required for Endometrial Stem Cells to Induce Peripheral Tolerance of Cardiac Allograft
*Purpose: The existing immunosuppressants seem to have little effect on Cardiac Allograft Vasculopathy but with obvious side effects. ERCs (Endometrial stem Cells), which are mesenchymal-like…2020 American Transplant Congress
High-Risk Antibodies Pre-Transplant Impacts Outcome after Heart Transplantation
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Pre-transplant circulating antibodies (Abs) are known to impact outcome after heart transplantation (HTx). Abs can now be detected by single-bead assay but also characterized…2020 American Transplant Congress
Safety and Efficacy of Prophylactic Valganciclovir Dosing after Solid Organ Transplant
Loyola University Medical Center, Maywood, IL
*Purpose: At centers where antiviral prophylaxis is used after solid organ transplant, valganciclovir is administered for the prevention of cytomegalovirus (CMV). At Loyola University Medical…2020 American Transplant Congress
The Frequency of De Novo DSA in the Years Following Heart Transplantation
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: The timing of the development of donor specific antibody (DSA) after heart transplantation is not clear. De novo DSA has been reported to be…
American Transplant Congress abstracts