Articles tagged "Heart/lung transplantation"

2020 American Transplant Congress
High-Risk Antibodies Pre-Transplant Impacts Outcome after Heart Transplantation
J. A. Kobashigawa, M. Kittleson, J. Patel, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, A. Shen, L. Czer, F. Esmailian
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Pre-transplant circulating antibodies (Abs) are known to impact outcome after heart transplantation (HTx). Abs can now be detected by single-bead assay but also characterized…
2020 American Transplant Congress
Safety and Efficacy of Prophylactic Valganciclovir Dosing after Solid Organ Transplant
K. Gandhi, D. Masic, M. Santarossa, F. Albarillo, N. Clark, G. Reid
Loyola University Medical Center, Maywood, IL
*Purpose: At centers where antiviral prophylaxis is used after solid organ transplant, valganciclovir is administered for the prevention of cytomegalovirus (CMV). At Loyola University Medical…
2020 American Transplant Congress
The Frequency of De Novo DSA in the Years Following Heart Transplantation
A. Shen, J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, K. Nishihara, L. Czer, F. Esmailian, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: The timing of the development of donor specific antibody (DSA) after heart transplantation is not clear. De novo DSA has been reported to be…
2020 American Transplant Congress
B Cell Derived IL-1β and IL-6 Drive Homeostatic T Cell Recovery Following Lymphoablation
S. Hasgur, R. Fan, A. Valujskikh
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: T cell reconstitution after lymphoablation in allograft recipients may lead to acute rejection and poor graft outcome. Using a mouse model of heart transplantation…
2020 American Transplant Congress
Molecular Profiles of Injury in Heart Transplant Allograft: Relationship to Rejection, Ejection Fraction, and Survival
P. Halloran¹, J. Reeve², &. the INTERHEART Study Group³
¹University of Alberta, Edmonton, AB, Canada, ²Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: In previous studies we used microarray analysis of gene expression to identify rejection in heart transplant endomyocardial biopsies, and found that this also revealed…
2020 American Transplant Congress
BK-Viral Nephropathy after Transplantation of a Non-Renal Organ
A. Schwarz¹, C. Bara², J. Braesen³, J. Gottlieb⁴
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Cardiothoracic Surgery Department, Hannover Medical School, Hannover, Germany, ³Pathology Department, Hannover Medical School, Hannover, Germany, ⁴Pulmonary Department, Hannover Medical School, Hannover, Germany
*Purpose: Patients with non-renal organ transplantation may suffer BK-viral nephropathy (BKVN) of their orthotopic kidneys by reactivation of their own viral population living in latency…
2020 American Transplant Congress
Effects of Donor Heavy Alcohol Use on Post-Heart Transplant Outcomes: Time to Abstain?
J. Patel, M. Kittleson, D. Chang, E. Kransdorf, D. Geft, A. Shen, K. Nishihara, G. Jamero, L. Czer, F. Esmailian, J. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Donors with a history of heavy alcohol use have been suspected to possibly harbor a subclinical alcoholic cardiomyopathy with limited cardiac reserve. This problem…
2020 American Transplant Congress
Agonistic Anti-CD272 Antibody (6B2) Suppressed Donor Specific Antibody Through Inducible Regulatory T Cells
Y. Yamamoto¹, M. Uchiyama², K. Uchida³, H. Yagita⁴, M. Niimi¹
¹Surgery, Teikyo University, Tokyo, Japan, ²Cardiovascular Surgery, Teikyo University, Tokyo, Japan, ³Hepato- Biliary- Pancreatic Surgery, Juntendo University, Tokyo, Japan, ⁴Immunology, Juntendo University, Tokyo, Japan
*Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) is a coinhibitory molecule and may play an important role in alloimmune responses. We…
2020 American Transplant Congress
Heart Transplant Outcomes in Patients Who Receive Hepatitis B Virus-Positive Donor Hearts: A UNOS Registry Analysis
P. Genyk¹, K. Yang², R. Chand³, E. Depasquale¹
¹Keck Medicine of USC, Los Angeles, CA, ²Keck Medicine of USC, South Pasadena, CA, ³Harbor-UCLA Medical Center, Los Angeles, CA
*Purpose: Hepatitis B infection in post-transplant patients posed a challenge in the setting of immunosuppression. However, the advent of anti-viral therapy for HBV has made…
2020 American Transplant Congress
Life Supporting Orthotopic Cardiac Xenotransplantation from Genetically Engineered Donor Pigs
A. K. Singh¹, C. E. Goerlich¹, T. Zhang¹, I. Tatarov¹, P. Odonkor¹, E. Strauss¹, B. Williams¹, B. Lewis¹, A. Hershfeld¹, F. Sentz¹, D. Ayares², D. Kaczorowski¹, B. Griffith¹, M. M. Mohiuddin¹
¹Department of Surgery, University of Maryland Baltimore, Baltimore, MD, ²Revivicor Inc, Blacksburg, VA
*Purpose: Cardiac xenotransplantation (CXTx) might be an alternative treatment for end-stage cardiac failure patients. The prolonged survival of a heterotopic genetically-engineered (GE) pig heart is…

« Previous Page
1
…
4
5
6
7
8
…
23
Next Page »