2021 American Transplant Congress
Novel Morphologic Biomarkers of Cardiac Allograft Remodeling are Associated with Multiple Peri- and Post-transplant Inflammatory Processes
*Purpose: It has long been recognized that transplanted hearts develop a stiffened, restrictive physiology at an accelerated rate compared to native hearts. While this is…2021 American Transplant Congress
Anti-CD272 Antibody (6B2) Generated Foxp3+Regulatory T Cells and Suppressed Donor Specific Antibody in Murine Cardiac Transplant Model
*Purpose: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…2021 American Transplant Congress
Cold Perfusion for Ischemia Minimization Reduces Cardiac Injury in an Ex Vivo Xenoperfusion Model
1Massachusetts General Hospital, Boston, MA, 2Revivicor, Blacksburg, VA
*Purpose: Prior studies using Steen’s cold perfusion storage technique for heart ischemia minimization (IM) prevented initial xenograft dysfunction (IXD). Our pilot data evaluates the effect…2021 American Transplant Congress
Impact of New Onset Diabetes After Transplantation on Heart Transplant Recipients
*Purpose: The purpose of this study is to investigate New Onset Diabetes After Transplantation (NODAT) incidence and its impact on post-transplant prognosis in adult heart…2021 American Transplant Congress
Changes to Adult Heart Allocation Improve Candidate Stratification
*Purpose: Historically, heart allocation has been driven by waitlist (WL) mortality rather than post-transplant survival. On 10/18/2018 the Organ Procurement and Transplantation Network (OPTN) implemented…2021 American Transplant Congress
BKV-Associated Urothelial Carcinoma in Patients After Renal and Extrarenal Carcinoma
*Purpose: Polyomavirus BK (BKV) reactivation or transmission is a wellknown problem in renal transplant (TX) patients with BKV nephropathy and interstitial cystitis. The role of…2021 American Transplant Congress
Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis
Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China
*Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…2021 American Transplant Congress
Hepatitis E Diagnosis and Management After Liver, Kidney, or Heart Transplant: A Single Center Experience
1Wayne State University School of Medicine, Detroit, MI, 2Henry Ford Health System, Detroit, MI
*Purpose: Transplant-related Hepatitis E virus (HEV) infection is a rarely recognized entity with significant clinical importance given potential for chronic hepatitis post-transplant. We evaluated HEV…2021 American Transplant Congress
Quilty Lesions are Associated with a Tolerance Profile in Heart Allografts Biopsies
Pathology, UTSW Medical Ctr, Dallas, TX
*Purpose: Previously, in 42 cardiac allograft biopsies, we demonstrated that the presence of Foxp3+ innate and TGF- β + adaptive regulatory lymphocytes in Quilty lesions…2021 American Transplant Congress
Use of Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients: A Scoping Review
University of Missouri, Columbia, MO
*Purpose: Immune checkpoint inhibitors (ICI) are an emerging treatment for numerous advanced diseases, but their safety and efficacy in immunosuppressed transplant patients is not known.…
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