2022 American Transplant Congress
Status Exception Use in the New Seven-Tiered Heart Allocation System
*Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…2022 American Transplant Congress
Dendritic Cell Senescence as a Key Contributor to Transplant Rejection
1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…2022 American Transplant Congress
Fontan versus Non-Fontan Combined Heart-Liver Transplantation: Proceed but Cautiously
Vanderbilt University Medical Center, Nashville, TN
*Purpose: Combined heart-liver transplantation (CHLT) is increasing, corresponding with a growing prevalence of Fontan-associated end-organ damage. We aimed to describe our contemporary institutional experience with…2021 American Transplant Congress
Changes to Adult Heart Allocation Improve Candidate Stratification
*Purpose: Historically, heart allocation has been driven by waitlist (WL) mortality rather than post-transplant survival. On 10/18/2018 the Organ Procurement and Transplantation Network (OPTN) implemented…2021 American Transplant Congress
BKV-Associated Urothelial Carcinoma in Patients After Renal and Extrarenal Carcinoma
*Purpose: Polyomavirus BK (BKV) reactivation or transmission is a wellknown problem in renal transplant (TX) patients with BKV nephropathy and interstitial cystitis. The role of…2021 American Transplant Congress
Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis
Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China
*Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…2021 American Transplant Congress
Hepatitis E Diagnosis and Management After Liver, Kidney, or Heart Transplant: A Single Center Experience
1Wayne State University School of Medicine, Detroit, MI, 2Henry Ford Health System, Detroit, MI
*Purpose: Transplant-related Hepatitis E virus (HEV) infection is a rarely recognized entity with significant clinical importance given potential for chronic hepatitis post-transplant. We evaluated HEV…2021 American Transplant Congress
Quilty Lesions are Associated with a Tolerance Profile in Heart Allografts Biopsies
Pathology, UTSW Medical Ctr, Dallas, TX
*Purpose: Previously, in 42 cardiac allograft biopsies, we demonstrated that the presence of Foxp3+ innate and TGF- β + adaptive regulatory lymphocytes in Quilty lesions…2021 American Transplant Congress
Use of Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients: A Scoping Review
University of Missouri, Columbia, MO
*Purpose: Immune checkpoint inhibitors (ICI) are an emerging treatment for numerous advanced diseases, but their safety and efficacy in immunosuppressed transplant patients is not known.…2021 American Transplant Congress
Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality
Transplant, Washington University, Saint Louis, MO
*Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…
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