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American Transplant Congress abstracts

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Articles tagged "Heart/lung transplantation"

  • 2022 American Transplant Congress

    Status Exception Use in the New Seven-Tiered Heart Allocation System

    A. Plana1, A. Kanelidis1, W. F. Parker2, V. Jeevanandam3, C. Salerno3, B. Smith1, S. Kalantari1, S. Pinney1, J. Grinstein1

    1Cardiology, University of Chicago, Chicago, IL, 2Pulmonary/Critical Care, University of Chicago, Chicago, IL, 3Cardiac Surgery, University of Chicago, Chicago, IL

    *Purpose: The revised seven-tiered US heart allocation policy aimed to improve risk stratification to lower exception status use. However, recent literature has demonstrated that exceptions…
  • 2022 American Transplant Congress

    Dendritic Cell Senescence as a Key Contributor to Transplant Rejection

    J. Zhao1, X. Li1, S. Jung1, H. Zhang1, V. Kasinath1, J. Azzi1, P. Sage1, J. Bromberg2, R. Abdi1

    1Brigham and Women’s Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: Intra-graft inflammation initiated by ischemia-reperfusion injury (IRI) is an unavoidable consequence of transplantation surgery and constitutes a key source of alloimmune responses. IRI leads…
  • 2022 American Transplant Congress

    Fontan versus Non-Fontan Combined Heart-Liver Transplantation: Proceed but Cautiously

    I. A. Ziogas, W. K. Wu, M. Izzy, A. Shingina, C. Benson, K. L. Mishra, A. S. Shah, N. L. Do, W. G. McMaster, J. N. Menachem, S. P. Alexopoulos

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: Combined heart-liver transplantation (CHLT) is increasing, corresponding with a growing prevalence of Fontan-associated end-organ damage. We aimed to describe our contemporary institutional experience with…
  • 2021 American Transplant Congress

    Changes to Adult Heart Allocation Improve Candidate Stratification

    K. Bradbrook1, K. Lindblad1, R. R. Goff1, R. Daly2, S. Hall3

    1Research, United Network for Organ Sharing, Richmond, VA, 2Mayo Clinic, Rochester, MN, 3Baylor University Medical Center, Dallas, TX

    *Purpose: Historically, heart allocation has been driven by waitlist (WL) mortality rather than post-transplant survival. On 10/18/2018 the Organ Procurement and Transplantation Network (OPTN) implemented…
  • 2021 American Transplant Congress

    BKV-Associated Urothelial Carcinoma in Patients After Renal and Extrarenal Carcinoma

    A. Schwarz1, J. Schmitz2, J. Gottlieb3, C. Bara4, H. Haller1, J. Braesen2

    1Nephrology Department, Hannover Medical School, Hannover, Germany, 2Institute of Pathology, Hannover Medical School, Hannover, Germany, 3Department of Pneumology, Hannover Medical School, Hannover, Germany, 4Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany

    *Purpose: Polyomavirus BK (BKV) reactivation or transmission is a wellknown problem in renal transplant (TX) patients with BKV nephropathy and interstitial cystitis. The role of…
  • 2021 American Transplant Congress

    Mortality, Risk Factors, and Treatment of Covid-19 Infection in Solid Organ Transplants: A Systematic Review and Meta-analysis

    S. Yin, T. Song, Q. Zhong, T. Lin

    Urology Institute and Organ Transplantation Center, West China Hospital, Chengdu, China

    *Purpose: Outcomes for solid organ transplants (SOT) with COVID-19 have not been summarized, and prognostic factors for COVID-19 in SOT patients are not well established…
  • 2021 American Transplant Congress

    Hepatitis E Diagnosis and Management After Liver, Kidney, or Heart Transplant: A Single Center Experience

    M. Carter1, M. Fitzmaurice2, S. Yeddula2, A. Singh2, S. Nagai2, S. Jafri2

    1Wayne State University School of Medicine, Detroit, MI, 2Henry Ford Health System, Detroit, MI

    *Purpose: Transplant-related Hepatitis E virus (HEV) infection is a rarely recognized entity with significant clinical importance given potential for chronic hepatitis post-transplant. We evaluated HEV…
  • 2021 American Transplant Congress

    Quilty Lesions are Associated with a Tolerance Profile in Heart Allografts Biopsies

    J. Torrealba, S. Moore, S. Sathirareuangchai, L. De Las Casas, Q. Cai

    Pathology, UTSW Medical Ctr, Dallas, TX

    *Purpose: Previously, in 42 cardiac allograft biopsies, we demonstrated that the presence of Foxp3+ innate and TGF- β + adaptive regulatory lymphocytes in Quilty lesions…
  • 2021 American Transplant Congress

    Use of Immune Checkpoint Inhibitors in Solid Organ Transplant Recipients: A Scoping Review

    A. G. Anderson, M. Eubank, K. Murray

    University of Missouri, Columbia, MO

    *Purpose: Immune checkpoint inhibitors (ICI) are an emerging treatment for numerous advanced diseases, but their safety and efficacy in immunosuppressed transplant patients is not known.…
  • 2021 American Transplant Congress

    Acute Kidney Injury Requiring Dialysis in Heart Transplant Recipients is a Risk Factor for Graft Failure and Overall Mortality

    M. A. Merzkani, H. Murad, A. Pottebaum, A. Java, A. Malone, J. Schilling, A. Itoh, R. Delos Santos, T. Alhamad

    Transplant, Washington University, Saint Louis, MO

    *Purpose: Acute Kidney Injury (AKI) is a frequent complication of heart transplantation. However, with recent allocation changes, we have increasingly complex patients with a higher…
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