2018 American Transplant Congress
Cardiac MRI May Help to Determine When to Refer Heart Transplant Patients for Redo Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Small vessel coronary artery disease is known to cause fibrosis. However, it is not clear whether myocardial fibrosis detected on MRI is associated with…2018 American Transplant Congress
Do Recent Heart Transplant Patients Need to Reside Close to the Transplanting Center? A Look at the Impact of Commuting Times on Clinical Outcomes
Cedars Sinai Medical Center, Los Angeles.
Purpose: Compliance after heart transplantation (HTx) is crucial to ensure adequate drug dosing and avoidance of complications especially within the first six months. To ensure…2018 American Transplant Congress
Incidence of Pneumonitis in Heart Transplant Patients Started on a Proliferation Signal Inhibitor
Cedars Sinai Medical Center, Los Angeles.
Purpose: Proliferation signal inhibitors(PSI) have a high discontinuation rate due to side effects. PSI induced pneumonitis has been reported in 14% in renal cell carcinoma…2018 American Transplant Congress
Macrophage Depletion of RCMV-Latently Infected Allografts Ameliorates Accelerated Chronic Cardiac Rejection
1Abdominal Organ Transplantation, OHSU, Portland, OR; 2VGTI, OHSU, Portland, OR.
PurposeLatent donor rat cytomegalovirus (RCMV) infection accelerates chronic rejection (CR) in a heterotopic rat heart transplant model. RCMV latency is associated with an influx of…2018 American Transplant Congress
IVIG Induction May Be Helpful in Highly Sensitized Patients after Heart Transplantation
Cedars Sinai Medical Center, Los Angeles.
Purpose: Strategies for sensitized patients undergoing heart transplant include post-op anti-thymocyte globulin (ATG) induction therapy as well as intravenous immunoglobulin (IVIG). We sought to assess…2018 American Transplant Congress
Heart and Lung Transplantation Outcomes in HIV-Positive Recipients
Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…2018 American Transplant Congress
Left Ventricular Assist Devices Complicated by Gastrointestinal Bleeding and Outcomes on Transplant
Internal Medicine, Cardiac Surgery, Cardiology, Henry Ford Hospital, Detroit.
Left Ventricular Assist Devices (LVAD) are becoming the standard of care in advanced heart failure patients. However, despite ongoing advances in this technology, there remains…2018 American Transplant Congress
Superior Renal Function with CNI-Free Everolimus over Standard CNI-Based Regimen: 18 Months Data from the Randomized, Multi-Center MANDELA Trial in De Novo Heart Transplant Recipients
1Mandela Study Group, Germany; 2Novartis, Pharma, Germany.
Purpose: The MANDELA study (NCT00862979) was designed to assess the benefit on renal function of either CNI-free or CNI-minimized EVR-based regimen after early conversion of…2018 American Transplant Congress
Late Donor-Specific Antibody (Especially Class II) Development is Associated with an Increased Risk for Cardiac Allograft Vasculopathy
Cedars Sinai Medical Center, Los Angeles.
Purpose: Development of donor-specific antibodies (DSA) following heart transplantation (HTx) impacts rejection, cardiac allograft vasculopathy (CAV), and survival. In addition, the timing of Ab development…2018 American Transplant Congress
Cardiac Grafts from Insulin Resistant Donors Trigger a Heightened Immune Response via Excessive Induction of Autophagy
Background Heart transplantation remains the treatment of choice for many patients with medically refractory heart failure. The use of organs from patients with insulin resistant…
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