Articles tagged "Heart/lung transplantation"

2020 American Transplant Congress
Evaluation of the Discrimination of 13 Mortality Risk Scores after Heart Transplantation in a Contemporary UNOS Cohort
G. Coutance, J. Patel, E. Kransdorf, R. Levine, E. Passano, J. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Multiple pre-transplant scores aimed at stratifying the risk of death or allograft loss after heart transplantation have been developed over time but their use…
2020 American Transplant Congress
Cervical Total Arterial Anastomosis Mouse-to-Rat Heterotopic Heart Xenotransplantation
A. Ren, Z. Li, X. Zhang, R. Deng, Y. Ma
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China
*Purpose: Xenotransplantation is an effective way to solve the problem of donor shortage. However, clinical use of xenotransplantation is currently limited due to immunological challenges.…
2020 American Transplant Congress
Bariatric Surgery for Congestive Heart Failure Patients Improves Access to Transplantation and Long-Term Survival
R. A. Choudhury¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, D. Yoeli¹, K. R. Dumon³, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Colorado Hospital, Philadelphia, PA
*Purpose: Obese patients with congestive heart failure (CHF) are often denied access to heart transplantation until they obtain significant weight loss to achieve a certain…
2020 American Transplant Congress
p40 Homodimers Indirectly Induce Endogenous Donor-Reactive Memory CD8 T Cell Activation within High-Risk Cardiac Allografts and CTLA-4ig Resistant Graft Rejection via IL-15 Signaling
H. Tsuda, A. Valujskikh, R. Fairchild
Inflammation and Immunity, Cleveland Clinic, Cleveland, OH
*Purpose: We have reported that longer duration of cold ischemic storage (CIS) prior to transplant resulted in increased proliferation of endogenous donor-reactive CD8 T cells…
2020 American Transplant Congress
Comparison of Outcomes between Patients Bridged to Heart Transplantation with ECMO versus Those Not Bridged with ECMO During the Years 1985 to 2019
D. J. Miklin¹, A. D. Salimbangon², G. S. Liu¹, P. Banankhah¹, P. A. Genyk¹, P. Kingsford¹, R. R. Chand³, J. P. Li¹, D. Vucicevic⁴, A. S. Vaidya¹, K. Pandya¹, J. Rahman¹, M. Fong¹, L. Grazette¹, A. Kiankhooy¹, J. Nattiv¹, S. Hashmi¹, S. Nuno¹, J. Pizula¹, A. E. Lee¹, K. Yang¹, S. Shaw¹, E. DePasquale¹, W. M. Aaron⁵
¹LAC-USC, Los Angeles, CA, ²UCLA Medical Center, Los Angeles, CA, ³Harbor-UCLA Medical Center, Los Angeles, CA, ⁴Newark Beth-Israel Medical Center, Newark, NJ, ⁵University of Arizona Sarver Heart Center, Tucson, AZ
*Purpose: Some patients with cardiogenic shock require extracorporeal membrane oxygenation (ECMO) for successful bridging to heart transplantation (HT). Herein, we report on the outcomes and…
2020 American Transplant Congress
Comparing Two Methods of Minimally-Ischemic Cardiac Preservation in Life-Supporting Cardiac Xenotransplantation Model
C. E. Goerlich¹, A. Singh¹, D. Kaczorowski¹, M. Abdullah¹, B. Lewis¹, I. Tatarov¹, A. Hershfeld¹, T. Zhang¹, E. Strauss¹, P. Odonkor¹, B. Williams¹, D. Ayares², B. Griffith¹, M. Mohiuddin¹
¹Surgery, University of Maryland School of Medicine, Baltimore, MD, ²Surgery, Revivicor, Blacksburg, VA
*Purpose: Transplantation of organs from animals to humans (xenotransplantation) has been proposed to address the critical shortage of organs for transplantation. The use of genetically…
2020 American Transplant Congress
The Art Rather Than the Science of Non-HLA Antibody Mediated Rejection in Heart Transplantation: A Single Center Experience
A. Alam, S. Mckean, R. Patel, V. Darst, H. Zafar, C. Guerrero, M. Askar, T. Sam, S. Hall
Cardiology, Baylor University Medical Center, Dallas, TX
*Purpose: The role of non-HLA antibodies (Ab) in HLA-DSA negative antibody mediated rejection (AMR) following heart transplant (HTx) remains largely unknown.*Methods: Retrospective analysis of all…
2019 American Transplant Congress
Incidence and Risk of Allograft Rejection after Cardiac Transplantation in Left Ventricular Assist Device Patients
R. C. Patel¹, L. B. Cooper², S. D. Barnett², R. T. Cole², M. A. Psotka², A. Cochrane², S. Sinha², L. J. Bogar², S. S. Desai², P. Shah²
¹Virginia Commonwealth University School of Medicine, Inova Fairfax Hospital, Falls Church, VA, ²Department of Heart Failure and Transplant, Inova Heart and Vascular Institute, Falls Church, VA
*Purpose: Left ventricular assist devices (LVAD) are made of biomaterials that have been shown to cause allosensitization. Single center studies have suggested that patients bridged…
2019 American Transplant Congress
3-year Outcome Of Heart Transplantation In Patients With Amyloidosis
J. Patel, M. Kittleson, D. H. Chang, R. Levine, S. Dimbil, L. Czer, F. Esmailian, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Both amyloid light chain (AL) amyloidosis and transthyretin-related (TTR) amyloid are expanding indications for heart transplantation (HTx). In the past, AL amyloid, in particular,…
2019 American Transplant Congress
Correlation between Self-Reported Medication Adherence and Side Effects in Transplant Recipients
T. Harrison¹, K. Foster¹, N. Patel¹, H. Meadows¹, C. Perez¹, H. Corbo¹, J. Fleming¹, N. Pilch¹, D. DuBay², J. McGillicuddy², S. Nadig², V. Rohan², D. Taber¹
¹Pharmacy Services, Medical University of South Carolina, Charleston, SC, ²Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: Medication non-adherence (MNA) is a major risk factor for acute rejection and graft loss amongst all organ groups. It is unclear how medication side…

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