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American Transplant Congress abstracts

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Articles tagged "Heart"

  • 2016 American Transplant Congress

    Pre-Transplant Coronary Artery Disease: An Underestimated Risk Factor for Post-Transplant Mortality?

    D. Khadzhynov, F. Halleck, L. Lehner, M. Duerr, A. Kleinsteuber, K. Budde, O. Staeck.

    Nephrology, Charite Universitaetsmedizin, Berlin, Germany.

    Background: Coronary artery disease is a frequent comorbidity among transplant candidates. Limited data exist on the long-term outcomes of kidney transplant recipients (KTR) with pre-existing…
  • 2016 American Transplant Congress

    Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing.

    M. Colvin,1 M. Skeans,1 L. Robbins Callahan,2 L. Edwards,2 J. Zeglin,1 S. Silvestry,3 R. Davies,4 M. Farr,5 A. Israni,1 J. Rogers.6

    1SRTR, Minneapolis, MN; 2UNOS, Richmond, VA; 3Florida Hospital Transplant Institute, Orlando, FL; 4Nemours/A.I. duPont Hospital for Children, Wilmington, DE; 5Columbia University Medical Center, New York, NY; 6Duke University, Durham, NC.

    Heart allocation policy (OPTN policy 6) is in development. The Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tiered medical urgency algorithm, then investigated…
  • 2016 American Transplant Congress

    Cardiovascular Prognosis and Adverse Cardiac Events After Orthotopic Liver Transplantation.

    L. Potena, V. Manfredini, P. Prestinenzi, R. Alabrese, V. Bertuzzo, L. Borgese, M. Masetti, C. Morelli, F. Grigioni, A. Pinna.

    University of Bologna, Bologna, Italy.

    Cardiovascular (CV) disease is a major cause of morbidity and mortality among transplant candidate and recipients of noncardiac organs. Aiming to analyze the impact of…
  • 2016 American Transplant Congress

    Airway Inflammation and Symptoms in Children Following Liver and Heart Transplantation.

    A. Redmann,1 J. Bucuvalas,2 R. Wood,3 C. Chin,4 C. Hart.1

    1Otolaryngology, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH; 2Pediatric Liver Care Center, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH; 3Division of Pediatric Pulmonology, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH; 4Heart Institute, Cincinnati Childrens Hospital Medical Center, Cincinati, OH.

    Objectives: To describe the upper airway endoscopic findings of patients with stridor, stertor or sleep-disordered breathing after liver transplantation (LT) or heart transplantation (HT).Methods: Retrospective…
  • 2016 American Transplant Congress

    Pediatric Heart Transplantation Across a Positive Cross-Match Is Associated with High Rates of AMR but No Difference in Short Term Graft Loss, Dysfunction and Death (CTOTC-04 study).

    S. Webber,1 L. Addonizio,2 E. Blume,3 A. Dipchand,4 R. Shaddy,5 B. Feingold,6 C. Canter,7 D. Hsu,8 W. Mahle,9 A. Zeevi,6 K. Much,10 D. Ikle,10 H. Diop,11 J. Odim, MD, PhD, for CTOTC-04 Investigators.11

    1Vanderbilt, Nashville; 2Columbia Univ., NYC; 3Boston Children's, Boston; 4Sick Kids, Toronto, Canada; 5CHOP, Philadelphia; 6CHP of UPMC, Pittsburgh; 7Washington Univ., St. Louis; 8Children's Hospital, Montefiore, NYC; 9CHOA, Atlanta; 10Rho, Chapel Hill; 11NIAID/NIH, Bethesda.

    Sensitization is common in pediatric heart transplant (HT) candidates. Waitlist mortality is high if a prospective -ve CDC-crossmatch (XM) is required, but HT across a…
  • 2016 American Transplant Congress

    Development and Validation of a Molecular Microscope Diagnostic System (MMDx) for Heart Transplant Biopsies.

    P. Halloran,1 D. Kim,1 A. Loupy,2 J.-P. Duong Van-Huyen,2 P. Bruneval,3 L. Potena,4 O. Leone,4 J. Reeve.1

    1University of Alberta, Edmonton, Canada; 2Necker Hospital, Paris, France; 3Hopitaux de Paris, Paris, France; 4Bologna University, Bologna, Italy.

    The diagnosis of heart transplant rejection by histology in endomyocardial biopsies (EMB) is challenging. A molecular system (MMDx) has been developed to assess both T…
  • 2016 American Transplant Congress

    Clinical and Subclinical Cardiac Events After Kidney Transplantation (KTX).

    F. Cosio,1 H. Amer,1 M. Keddis,2 A. Jaffe.3

    1Transplant Center, Mayo Clinic, Rochester, MN; 2Nephrology, Mayo Clinic, Phoenix, AZ; 3Lab Medicine/Pathology, Mayo Clinic, Rochester, MN.

    Introduction. Elevated levels of the biomarker cardiac troponin T levels (cTNT) pre- KTX relates to high mortality and CV risk pre and post-KTX. We sought…
  • 2016 American Transplant Congress

    Predicting Obstructive Coronary Artery Disease in Asymptomatic Patients Undergoing Renal Transplantation Using a Simple Risk Score.

    D. Moutzouris, C. Baker, M. Willicombe, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    PurposeCoronary angiography in asymptomatic patients with End Stage Renal Disease (ESRD) shows significant Coronary Artery Disease (CAD) (stenosis >50%) in 37-53% of patients. We have…
  • 2016 American Transplant Congress

    Impact of Induction Therapy on Cardiovascular Events in Kidney Transplant Recipients.

    S. Sandal,1,2 S. Bae,2 A. Massie,2 M. Cantarovich,1 D. Segev.2

    1MUHC, Montreal, Canada; 2JHU, Baltimore.

    Cardiovascular events (CVE) are one of leading causes of mortality in kidney transplant (KT) recipients and ATG use is reported as a risk factor. We…
  • 2016 American Transplant Congress

    αLFA-1 Monotherapy Induced Tolerance Is Dependent on Indirect CD8 T-Cells and Augments a Population of CD8 Cells with a Suppressor Phenotype.

    R. Plenter,1 M. Coulombe,2 T. Grazia,1 R. Gill,2 M. Zamora,1 B. Pietra.3

    1Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO; 2Department of Surgery, University of Colorado, Aurora, CO; 3Division of Pediatric Cardiology, University of Florida, Gainesville, FL.

    We sought to investigate some of the requirements for tolerance induction to cardiac allografts utilizing αLFA-1 mAb monotherapy. Having previously demonstrated that CD8 T-cells are…
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