ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing.

M. Colvin,1 M. Skeans,1 L. Robbins Callahan,2 L. Edwards,2 J. Zeglin,1 S. Silvestry,3 R. Davies,4 M. Farr,5 A. Israni,1 J. Rogers.6

1SRTR, Minneapolis, MN
2UNOS, Richmond, VA
3Florida Hospital Transplant Institute, Orlando, FL
4Nemours/A.I. duPont Hospital for Children, Wilmington, DE
5Columbia University Medical Center, New York, NY
6Duke University, Durham, NC.

Meeting: 2016 American Transplant Congress

Abstract number: C71

Keywords: Allocation, Heart

Session Information

Date: Monday, June 13, 2016

Session Name: Poster Session C: Economics, Public Policy, Allocation, Ethics

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Halls C&D

Related Abstracts
  • Thoracic Simulation Allocation Modeling (TSAM) of a 6-Tier Allocation Strategy.
  • Broader Geographic Sharing of Adolescent Lung Donors Improves Allocation Efficiency

Heart allocation policy (OPTN policy 6) is in development. The Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tiered medical urgency algorithm, then investigated 4 broader geographic sharing strategies. We determined the impact of modified geographic orderings on transplant rates and mortality rates.

Using TSAM software and OPTN data, we determined the relative impact of 4 geographic orderings, using a 6-tiered medical urgency algorithm, on transplant rates and on waitlist and posttransplant mortality rates. Results were compared with the current allocation rules and allocation under the 6-tier urgency algorithm. The study included 8885 heart and 141 heart-lung candidates listed for at least 1 day from July 1, 2009-June 30, 2011.

Simulations of broader sharing showed substantially higher transplant rates in the sickest candidates (tiers 1 and 2) but slightly lower rates across all tiers. It produced lower waitlist mortality rates than simulation using current rules, but similar posttransplant mortality rates. Transplant rates increased from 615 per 100 pt-yrs under current rules to 3044 under allocation by tiers, to 7627-7999 under the 4 broader sharing rules in tier-1 candidates. Corresponding increases in tier-2 candidates were 589 to 2363 to 5647-5996 (Figure). In tiers 1-6, waitlist mortality under broader sharing was similar to current rules. Broader sharing decreased waitlist deaths among inactive candidates, contributing to overall lower waitlist mortality.

Broader sharing showed substantially higher transplant rates in the sickest candidates than current allocation rules and than allocation by tiers under current geographical ordering. Overall waitlist morality rates were lower and posttransplant mortality rates were similar. Broader sharing may increase transplants in the most critically ill patients while decreasing waitlist mortality.

CITATION INFORMATION: Colvin M, Skeans M, Robbins Callahan L, Edwards L, Zeglin J, Silvestry S, Davies R, Farr M, Israni A, Rogers J. Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Colvin M, Skeans M, Callahan LRobbins, Edwards L, Zeglin J, Silvestry S, Davies R, Farr M, Israni A, Rogers J. Thoracic Simulated Allocation Modeling (TSAM) of Broader Sharing. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/thoracic-simulated-allocation-modeling-tsam-of-broader-sharing/. Accessed February 28, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.