Articles tagged "Heart"

2020 American Transplant Congress
Association between Homograft Tissue Exposure and Pre-Sensitization Prior to Heart Transplant in Patients with Congenital Heart Disease
D. J. Donovan¹, M. E. Richmond², E. A. Bacha³, L. J. Addonizio², W. A. Zuckerman²
¹Pediatrics, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, ²Pediatric Cardiology, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY, ³Pediatric Cardiac Surgery, NewYork-Presbyterian Hospital, Columbia University Irving Medical Center, New York, NY
*Purpose: Surgical repair for patients with congenital heart disease (CHD) often incorporates homograft tissue or other biologic material, which can lead to pre-sensitization. We sought…
2020 American Transplant Congress
Epidemiology of Invasive Fungal Infections in Heart Transplant Recipients
A. Couture-Cossette¹, A. Puing¹, A. Multani², O. Quintero¹, A. K. Subramanian¹, E. Henricksen³, R. Lee¹, Y. Moayedi⁴, K. Khush⁵, J. J. Teuteberg⁵, D. Y. Ho¹
¹Department of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ²Department of Infectious Diseases, UCLA, Stanford, CA, ³Pharmacy, Stanford Healthtcare, Stanford, CA, ⁴Department of Cardiology, UHN, Toronto, ON, Canada, ⁵Division of Cardiology, Department of Medicine, Stanford University, Stanford, CA
*Purpose: The incidence and epidemiology of invasive fungal infections (IFI) after heart transplantation (HTx) are influenced by changes in environmental exposures, immunosuppression, and prophylaxis practices.…
2020 American Transplant Congress
Desensitization Combining Costimulation Blockade with Proteasome Inhibition in Highly Sensitized Transplant Candidates
S. Restaino¹, D. Jennings², G. Serban³, E. Vasilescu³, G. Sayer¹, N. Uriel¹, K. Takeda⁴, Y. Naka⁴, M. Farr¹, M. V. Habal¹
¹Cardiology, Columbia University Irving Medical Center, New York, NY, ²School of Nursing, Columbia University Irving Medical Center, New York, NY, ³Pathology&Cell Biology, Columbia University Irving Medical Center, New York, NY, ⁴Cardiothoracic Surgery, Columbia University Irving Medical Center, New York, NY
*Purpose: Antibodies to human leukocyte antigens (HLA) pose a significant barrier to transplantation. Strategies to reduce allosensitization have modest efficacy and may result in antibody…
2019 American Transplant Congress
Myeloid AXL Promotes Cardiac Allograft Vasculopathy
K. E. Glinton¹, X. Yeap¹, Z. J. Zhang², X. Luo³, E. B. Thorp¹
¹Pathology, FCVRRI, Northwestern University - Feinberg School of Medicine, Chicago, IL, ²Surgery, Northwestern University - Feinberg School of Medicine, Chicago, IL, ³Duke Transplant Center, Duke University School of Medicine, Durham, NC
*Purpose: Cardiac Allograft Vasculopathy (CAV) is a significant contributor to long term transplant rejection, despite advances in immunotherapy. Reactivity to alloantigen presentation may occur by…
2019 American Transplant Congress
First Experience For Cold Storage Of Donor Hearts With Paragonix SherpaPak
L. Stastny¹, M. Kofler¹, D. Höfer¹, G. Pölzl², R. Breitkopf³, M. Grimm¹, H. Antretter¹, J. Dumfarth¹
¹Cardiac Surgery, Medical University Innsbruck, Innsbruck, Austria, ²Internal Medicine, Medical University Innsbruck, Innsbruck, Austria, ³Intensive Care Unit, Medical University Innsbruck, Innsbruck, Austria
*Purpose: Preservation of donor organs is a crucial component for the maintenance of viability after explantation. The current standard for transporting a donor organ includes…
2019 American Transplant Congress
What Are You Smoking? The Impact of Donor Drug Use on Long Term Survival Post-Transplant
D. A. Baran¹, A. Long¹, J. T. Lansinger², H. Copeland³, J. M. Herre¹, W. Old¹, G. Zeevi¹, C. Barreiro¹, C. Kemp¹, B. H. Smith¹, K. Stelling¹, A. Ingemi¹, P. Bourassa¹, J. Philpott¹
¹Sentara Heart Hospital, Norfolk, VA, ²Eastern Virginia Medical School, Norfolk, VA, ³Division of Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson, MS
*Purpose: Drug use is a common aspect in the history of heart transplant donors. Whether prior or current drug use is associated with inferior post…
2019 American Transplant Congress
The Use Of First-year Intravascular Ultrasound In The Tacrolimus Era In Heart Transplantation
S. Dimbil¹, M. Kittleson¹, J. Patel¹, D. Geft¹, R. Cheng¹, R. Levine¹, T. Sato¹, L. Czer¹, R. Zabner², P. Zakowski², J. A. Kobashigawa¹, B. Azarbal¹
¹Cedars-Sinai Smidt Heart Institute, Los Angeles, CA, ²Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Cytomegalovirus (CMV) has been documented as a risk factor for the development of cardiac allograft vasculopathy (CAV) after heart transplantation (HTx). It has not…
2019 American Transplant Congress
Donors and Drugs: How Often Do They Mix? Utilization of Donors Based on Toxicology Findings
J. T. Lansinger¹, A. Long¹, C. Barreiro², J. M. Herre², H. Copeland³, W. Old², G. Zeevi², C. D. Kemp², J. M. Philpott², K. Stelling², A. Ingemi², B. H. Smith², P. Bourassa², D. A. Baran²
¹Eastern Virginia Medical School, Norfolk, VA, ²Sentara Heart Hospital, Norfolk, VA, ³Division of Cardiothoracic Surgery, University of Mississippi Medical Center, Jackson, MS
*Purpose: Despite an increasing number of patients waiting for heart transplantation, the growth of transplant volume has risen slowly. The opioid crisis has resulted in…
2019 American Transplant Congress
What is the Post-Heart Transplant Risk of Infectious Complications from Pre-Transplant Desensitization Therapy?
E. Kransdorf, J. Patel, S. Dimbil, R. Levine, D. H. Chang, J. A. Kobashigawa
Cedars-Sinai Smidt Heart Institute, Los Angeles, CA
*Purpose: Sensitization or the detection of circulating antibodies in heart transplant candidates appears to be increasing due to the growing use of mechanical circulatory support…
2019 American Transplant Congress
How Do We Choose? Predicting Utilization Of Cardiac Donors And The Effect Of Era
D. A. Baran¹, J. T. Lansinger², A. Long², J. Philpott³, H. Copeland⁴, W. Old³, G. Zeevi³, C. Barreiro³, C. Kemp³, B. H. Smith³, K. Stelling³, A. Ingemi³, P. Bourassa³, J. M. Herre³
¹Sentara Heart Hospital, Virginia Beach, VA, ²Eastern Virginia Medical School, Norfolk, VA, ³Sentara Heart Hospital, Norfolk, VA, ⁴University of Mississippi Medical Center, Jackson, MS
*Purpose: The number of patients on the heart transplant waitlist continues to rise. However, the rate of organ acceptance is only about 1/3 of all…

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