Articles tagged "Heart transplant patients"

2016 American Transplant Congress
A Risk Quantification Score for Heart Transplants: A Heart Donor Risk Index.
A. Israni,^1,2 D. Zaun,¹ J. Snyder,¹ N. Salkowski,¹ H. Xiong,¹ B. Kasiske,^1,2 M. Colvin,^1,3 M. Colvin.^1,3
¹Scientific Registry of Transplant Recipients, Minneapolis; ²Hennepin County Medical Center, Univ of MN, Minneapolis; ³Univ of Michigan, Ann Arbor.
Background: To better risk stratify heart transplants, we developed a continuous heart donor risk index (HDRI) based on heart donors to quantify heart allograft failure.Methods:…
2016 American Transplant Congress
Relationship Between Changes in Brain Natriuretic Peptide Levels and Cardiac Allograft Rejection Early After Heart Transplantation.
J. Dann,¹ K. Deininger,¹ D. Reinhold,¹ R. Page II,¹ A. Ambardekar,¹ J. Lindenfeld,² C. Aquilante.¹
¹University of Colorado, Aurora, CO; ²Vanderbilt University, Nashville, TN.
Endomyocardial biopsies (EMBs) are routinely used to detect cardiac allograft rejection after heart transplantation (HTx), but they are invasive and costly. Serial changes in brain…
2016 American Transplant Congress
Dilution of Patient Sera Improves MFI Correlation with Complement Fixation in Solid Phase Assay Assessment.
C. Castleberry,¹ D. Phelan,² K. Simpson,¹ T. Mohanakumar,³ C. Canter.¹
¹Pediatric Cardiology, Washington University School of Medicine, St. Louis, MO; ²Histocompatibility Laboratory, Barnes-Jewish Hospital, St. Louis, MO; ³Surgery, Washington University School of Medicine, St. Louis, MO.
Background: Median Fluorescent Intensity (MFI) by solid phase assays (SPA) has been used to determine risk of donor-recipient reaction prior to transplant. Inconsistency of this…
2016 American Transplant Congress
Gene Expression Profiling Score and the Risk of Infection in Heart Transplant Recipients.
J. Teuteberg,¹ D. Budge,² M. Shullo,¹ S. Hall,³ J. Kobashigawa.⁴
¹University of Pittsburg, Pittsburgh, PA; ²Intermountain Medical Center, South Lake City, UT; ³Baylor University Medical Center, Dallas, TX; ⁴Cedars-Sinai Heart Institute, Los Angeles, CA.
Purpose: This study assessed the association of gene expression profiling (GEP, AlloMap®) score with infections in heart transplant recipients (HTR). Although a GEP score below…
2016 American Transplant Congress
Pregnancy Outcomes in 17 Female Heart Transplant Recipients with the Initial Diagnosis of Congenital Heart Defect.
L. Coscia,¹ D. Armenti,¹ S. Constantinescu,^1,2 M. Moritz.^1,3
¹Gift of Life Institute, National Transplantation Pregnancy Registry (NTPR), Philadelphia; ²Medicine, Temple University, Philadelphia; ³Surgery, Lehigh Valley Health Network, Allentown.
The purpose of this study was to describe pregnancy in female heart recipients whose indication for transplantation was due to congenital heart defect. Data were…
2016 American Transplant Congress
Characterization of T Regulatory Type 1 (Tr1) Cells in Naïve and Transplanted Non-Human Primates.
R. Yu, M. Tonsho, P. Spencer, S. Bernard-Stoecklin, G. Benichou, J. Madsen.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
BackgroundT regulatory Type 1 (Tr1) cells are peripheral CD4+FoxP3- regulatory T cells expressing CD49b and LAG-3 in mice and humans. Mouse Tr1 cells inhibit antigen-presenting…
2016 American Transplant Congress
Qualitative Assessment of Patient-Perceived Treatment Burden Following Cardiac Transplantation.
K. Deininger,¹ J. Reich,¹ J. Hirsch,² S. Graveline,² A. Feist,² J. LaFleur,³ S. Smith,⁴ A. Ambardekar,¹ J. Lindenfeld,⁵ C. Aquilante.¹
¹University of Colorado, Aurora, CO; ²University of California San Diego, La Jolla, CA; ³University of Utah, Salt Lake City, UT; ⁴University of Florida, Gainesville, FL; ⁵Vanderbilt University, Nashville, TN.
Patient-perceived treatment burden (PPTB), i.e., “the work of being a patient,” following heart transplantation (HTx) can affect patients' experiences of care, sense of self-efficacy in…
2016 American Transplant Congress
High-Risk Age Window for Graft Loss in Pediatric Lung and Heart Transplant Recipients.
B. Orandi, X. Luo, K. Van Arendonk, R. Higgins, D. Segev.
Johns Hopkins University, Baltimore.
Late adolescence and early adulthood is a high-risk age window for pediatric kidney graft loss, though not for pediatric liver graft loss. It is unknown…
2016 American Transplant Congress
Donor-Recipient Race Matching Is Not Associated with Recipient Survival Following Heart Transplantation.
C. Evans,¹ P. Sanchez,¹ Z. Kon,¹ E. Feller,² B. Griffith,¹ S. Pham.¹
¹Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD; ²Medicine, Division of Cardiovascular Medicine, University of Maryland School of Medicine, Baltimore, MD.
Purpose: The implications of donor and recipient race matching in heart transplantation are not clear. The objective of this communication is to quantify the association…
2016 American Transplant Congress
Assessment of Postoperative Glycemic Control in Orthotopic Heart Transplant Recipients.
J. Glick Frasiolas, J. Matthew, D. Tsapepas.
NewYork-Presbyterian Hospital, Columbia University, New York.
Hyperglycemia may occur after solid organ transplantation because of stress, immunosuppressants, and diabetes mellitus. Glycemic control has been shown to decrease morbidity and mortality in…