Articles tagged "Graft survival"

2016 American Transplant Congress
Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.
A. Mehta,¹ A. Marriott,¹ A. Ghazanfar.²
¹St. George's, University of London, London, United Kingdom; ²Renal Transplant Unit, St. George's Hospital, London, United Kingdom.
This study aims to analyze our renal transplant recipient population in terms of perioperative complications (90 day) and graft survival (3 years) in relation to…
2016 American Transplant Congress
Long Term Heterotopic Cardiac Xenograft Survival from Donor Pigs with Six Gene Modifications.
M. Mohiuddin,¹ A. Singh,¹ J. Chan,¹ P. Corcoran,¹ M. Thomas III,² B. Lewis,² D. Ayares,³ K. Horvath.¹
¹CSRP, NHLBI/NIH, Bethesda, MD; ²DVR / RS, NIH, Bethesda, MD; ³Revivicor, Inc, Blacksburgh, VA.
Introduction: We have recently reported pig xenograft survival of more than 2.5 years in a heterotopic cardiac xenograft model. Some of the animals exhibited local…
2016 American Transplant Congress
The UKKDRI Score Predicts Outcomes of Deceased Donor Transplantation Using a Steroid Sparing Immunosuppressive Protocol.
A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.
Imperial College REnal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
The UK kidney donor risk-index (UKKDRI) was developed to provide a simplistic clinical tool to help determine quality of an allograft and aid informed consent.…
2016 American Transplant Congress
Risk Stratification for Optimized Utilization of Deceased Donor Kidneys with Acute Kidney Injury by KDIGO Criteria.
B. Yu,¹ T. Koo,² J. Lee,³ J. Yang,² J. Ha,⁴ C. Ahn,¹ Y. Kim,¹ H. Lee.¹
¹Internal Medicine, Seoul National University Hospital, Seoul, Korea; ²Transplantation Center, Seoul National University Hospital, Seoul, Korea; ³Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁴General Surgery, Seoul National University Hospital, Seoul, Korea.
BackgroundDeceased donor kidneys with acute kidney injury (AKI) raise fear of poor graft outcomes to the transplant clinicians and consequently are often discarded. However, the…
2016 American Transplant Congress
Innate Immune Signaling During Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation.
R. Sosa,¹ A. Zarrinpar,² C. Lassman,¹ R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,¹ E. Reed.¹
¹Pathology and Lab Medicine, University of California-Los Angeles, Los Angeles, CA; ²Surgery, University of California-Los Angeles, Los Angeles, CA.
Background: Orthotopic liver transplantation (OLT) success is hampered by cellular damage elicited by ischemia-reperfusion injury (IRI) which lowers allograft survival. Research using murine models has…
2016 American Transplant Congress
The Association of Life Expectancy by Resident Zip Code and Kidney Transplant Outcomes – What Is True Baseline Risk?
L. Buccini, D. Goldfarb, E. Poggio, S. Flechner, J. Schold.
Cleveland Clinic, Cleveland, OH.
Many factors beyond traditional clinical risk factors and demographics are associated with outcomes in the general population. These include behavioral, economic, genetic and environmental risks…
2016 American Transplant Congress
Smoking Exposure Among Kidney Allograft Recipients and Outcomes After Transplant.
H. Gillott,¹ S. Tahir,¹ F. Jackson-Spence,¹ F. Evison,² J. Nath,³ A. Sharif.³
¹Medical School, University of Birmingham, Birmingham, United Kingdom; ²Medical Informatics, Queen Elizabeth Hospital, Birmingham, United Kingdom; ³Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom.
The causal effects of smoking on major comorbidity and mortality in the general population are well established. However, the influence of smoking exposure on kidney…
2016 American Transplant Congress
Kidney Donor Profile Index Trend Analyses.
D. Vikraman, K. Ravindra, S. Sanoff, W. Irish, U. Patel, D. Sudan.
Surgery, Duke University Medical Center, Durham, NC.
IntroductionIn spite of improved outcomes associated with the usage of extended criteria donor (ECD) kidneys, the number of kidney transplants (KT) using this donor population…
2016 American Transplant Congress
Analysis of Local versus Imported Expanded Criteria Donor (ECD) Kidneys: A Single Center Experience with 497 ECD Kidney Transplants.
M. Khan,¹ H. El-Hennawy,¹ A. Farney,¹ J. Rogers,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² M. Gautreaux,³ S. Iskandar,³ W. Doares,⁴ S. Kaczmorski,⁴ R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC; ³Pathology, Wake Forest, Winston-Salem, NC; ⁴Pharmacy, Wake Forest, Winston-Salem, NC.
With the new Kidney Allocation System, broader sharing of expanded criteria donor (ECD) kidneys may occur, which may influence discard rates and survival outcomes. To…
2016 American Transplant Congress
Age Gap Analysis Between Live Donor and Recipients in Kidney Transplantation: Opportunities to Improve Voluntary Exchange Programs and Kidney Paired Donation.
J. Rodriguez,¹ A. Patel,² M. Goggins.²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI; ²Transplant Institute, Henry Ford Hospital, Detroit, MI; ³Transplant Institute, Henry Ford Hospital, Detroit, MI.
Graft survival(GS) perception is that, with a smaller age gap between the donor(D) and recipient(R), better the outcome. It is unclear if there is an…