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Articles tagged "Graft survival"

  • 2016 American Transplant Congress

    Outcomes with the Use of Pediatric Donor Livers in Adult Recipients: Review of the UNOS Database.

    K. Croome, D. Lee, J. Burns, J. Nguyen, D. Perry, C. Taner.

    Transplant, Mayo Clinic Florida, Jacksonville, FL.

    Background: While there is an agreement that pediatric donor (PD) livers should ideally be used for pediatric recipients, there remain some situations where these livers…
  • 2016 American Transplant Congress

    Patients with ESRD Due to Diabetes Have Higher Variability of Their Tacrolimus Levels and Worse Outcomes.

    D. Goodall, M. Willicombe, A. McLean, D. Taube.

    Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.

    IntroductionNonadherence to immunosuppressants is associated with rejection and graft loss and nonadherence to antidiabetics is associated with poor glycaemic control leading to microvascular complications and…
  • 2016 American Transplant Congress

    Urinary Virome in Human Kidney Transplants Reveals Multiple Virus Subtypes with Distinct Genome Polymorphisms.

    R. Ranjan,1 A. Rani,1 H. McGee,1 D. Brennan,2 P. Finn,1 D. Perkins.1,3

    1Medicine, University of Illinois, Chicago, IL; 2Division of Renal Diseases, Washington University School of Medicine, St. Louis, MO; 3Surgery, University of Illinois, Chicago, IL.

    Recent studies have established that human urine has its own unique microbiome, but little is known about the virome. The human virome is the collection…
  • 2016 American Transplant Congress

    Fecal Microbiota Transplant Results in Durable Changes to Host Microbiota That Correlate with Allograft Outcome.

    C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.

    CVID and IGS, University of Maryland School of Medicine, Baltimore, MD.

    Hypothesis: We previously presented highly significant differences in the bacterial community structures of human renal allograft recipients over time. Likewise, murine normal, colitic, and pregnant…
  • 2016 American Transplant Congress

    Machine Perfusion (MP) at 21[deg]C Simulates Hibernation Metabolic Pathways in a Non-Hibernator Mammal.

    B. Banan, S. Dobrowolski, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Background: Hibernation is a complex and multi stage process that leads to unique metabolic changes over an extended period of time. Regulatory genes and transcription…
  • 2016 American Transplant Congress

    The Oldest and Coldest in Kidney Paired Donation: Experience of the National Kidney Registry.

    N. Nassiri,1 L. Kwan,1 J. Sinacore,2 J. Veale.1

    1Urology, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2National Kidney Registry, Babylon, NY.

    OBJECTIVES: To evaluate renal allograft efficacy and survivability in elderly donors and prolonged cold ischemia time (CIT).METHODS: 1,402 living donor kidney transplants from 02/2008-06/2015 recorded…
  • 2016 American Transplant Congress

    Evolving to Everolimus: A Safe and Effective Option for Pancreas Transplant.

    S. Yeager, A. Carlson, C. Truax, N. Kenyon, F. Ahmed, J. Corbett, F. Shihab, L. Smith.

    University of Utah Health Care, Salt Lake City, UT.

    Although everolimus is an attractive option for conversion therapy in pancreas tx pts that experience SE's of commonly used immunosuppression, TAC and MPA, there is…
  • 2016 American Transplant Congress

    Refill-Based Immunosuppression Non-Adherence Is Associated with Increased Death Censored Graft Loss.

    K. Wen, S. Gourishankar, S. Shojai, A. Wong, M. Bae, D. Grynoch, P. Halloran.

    Medicine, University of Alberta, Edmonton, AB, Canada.

    Introduction Medication non-adherence is a major contributor of graft loss in kidney transplant(KTX) recipients. We aim to evaluate the association of immunosuppression non-adherence to graft…
  • 2016 American Transplant Congress

    Heterologous Persistent and Latent Viral Infections Do Not Impact Graft Survival.

    J. Espinosa,1,2 M. McRae,1 J. Wang,1 A. Kirk.1

    1Duke University, Durham; 2Emory University, Atlanta.

    Purpose: Infection induces costimulation-resistant memory T cells with heterologous alloreactivity. Rapamycin has been shown to mitigate the effect of these cells in transplant rejection. Previous…
  • 2016 American Transplant Congress

    Prolonged Pre-Transplant Dialysis Duration Reverses the “Nephroprotective Effect” in Simultaneous Liver-Kidney Transplant Recipients.

    M. Casey, X. Wen, A. Santos, S. Rehman, K. Womer.

    University of Florida, Gainesville.

    Past literature has suggested that simultaneous liver-kidney(SLK) transplant recipients may experience a nephroprotective effect compared to kidney(Ki) alone transplant recipients. Since hepatorenal syndrome is a…
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