ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Does Gender Affect Renal Transplant Outcomes?

    A. Patel, R. Prashar.

    Department of Internal Medicine, Division of Nephrology, Henry Ford Transplant Institute, Detroit, MI

    Many studies have evaluated the role of gender on renal transplantation.Females (F) are less likely than males (M) to be on the waitlist (WL); less…
  • 2017 American Transplant Congress

    Heat Shock Protein 90 Inhibitor, 17DMAG Suppresses Acute Allograft Rejection and Prolongs Allograft Survival in Solid Organ Transplantation.

    T. Maehana, T. Tanaka, N. Masumori.

    Urology, Sapporo Medical University School of Medicine, Sapporo, Japan

    Purpose: Heat shock protein 90 (HSP90) is a ubiquitously expressed molecular chaperone that is associated with the correct activation of client proteins. Important roles of…
  • 2017 American Transplant Congress

    Small Pediatric Donor Kidney Transplantation in Pediatric Recipients.

    H. Yaffe,1,2 P. Friedmann,2 L. Kayler.3

    1Surgery, Montefiore Medical Center, Bronx, NY; 2Surgery, Albert Einstein College of Medicine, Bronx, NY; 3Surgery, Erie County Medical Center, Buffalo, NY

    Kidneys from small pediatric donors (age <5 years, weight <21 kg) may be a means to increase the donor pool for pediatric recipients. Transplantation of…
  • 2017 American Transplant Congress

    Long-Term Liver and Kidney Survival Following Combined Liver-Kidney Transplantation, with or without Preformed Donor-Specific Antibodies.

    A. Del Bello,1 O. Bestard,2 J. Visentin,3 N. Congy-Jolivet,1 L. Couzi,3 M. Neau-Cransac,3 F. Jambon,3 N. Kamar.1

    1Nephrology and Organ Transplant Department, CHU Toulouse, Toulouse, France; 2Nephrology and Kidney Transplant Department, Bellvitge University Hospital, Barcelona, Spain; 3Nephrology and Kidney Transplant Department, CHU Bordeaux, Bordeaux, France

    Introduction: Successful kidney transplantation despite a positive crossmatch is well known after combined liver-kidney transplantation (CLKT). However, recently, concerns regarding the impact of preformed anti-HLA…
  • 2017 American Transplant Congress

    Induction of Delayed Renal Allograft Tolerance Using Only Clinically Available Reagents in Non-Human Primates.

    K. Hotta, T. Oura, A. Dehnadi, S. Boskovic, M. Matsunami, I. Rosales, N. Smith, R. Colvin, A. Cosimi, T. Kawai.

    Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA

    Background: We have previously reported successful induction of renal allograft tolerance following a period of conventional immunosuppression (Delayed tolerance) using nonmyeloablative conditioning that included anti-CD154…
  • 2017 American Transplant Congress

    Pregnancy After Kidney-Pancreas Transplantation: Maternal and Offspring Outcomes.

    S. Rao,1 L. Coscia,2 D. Armenti,2 S. Constantinescu,1,2 M. Moritz.2,3,4

    1Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; 2Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA; 3Surgery, Lehigh Valley Health Network, Allentown, PA; 4Morsani College of Medicine, USF, Tampa

    This study analyzed 109 pregnancies (116 outcomes) in 62 female kidney-pancreas (KP) recipients reported to the Transplant Pregnancy Registry International (TPR). Data were collected via…
  • 2017 American Transplant Congress

    A Combination of Anti-CD40L-Ab, Rapamycin, and Donor Apoptotic Cells Prolongs Allogeneic Pancreatic Islet Survival in Sensitized Mice by Regulating Memory Responses.

    A. Dangi,1 H.-K. Kang,1 X. Zhang,2,3 X. Luo.1,2,3

    1Nephrology and Hypertension, Northwestern University, Chicago, IL; 2Comprehensive Transplant Center, Northwestern University, Chicago, IL; 3Surgery, Northwestern University, Chicago, IL

    Accelerated rejection of allografts has been a clinical challenge in solid organ transplantation particularly in sensitized recipients with donor-specific antibodies (DSA) and memory cell repertoires.…
  • 2017 American Transplant Congress

    Presence of Complement Activating Donor Specific Antibodies Is Associated with Poor Renal Allograft Survival: Two Centre Retrospective Study.

    A. Babu,1,4,5 O. Shaw,2 L. Howe,2 N. Kessaris,3 A. Dorling,3 N. Mamode,3 R. Vaughan,2 N. Krishnan,5 R. Higgins,5 D. MItchell,1 D. Briggs,4 S. Daga.1,5,6

    1Warwick Medical School, University of Warwick, Coventry, United Kingdom; 2Clinical Transplantation Laboratories, Guy's Hospital, Viapath, London, United Kingdom; 3Nephrology and Transplantation, Guy's Hospital, London, United Kingdom; 4Histocompatibility and Immunogenetics, NHS Blood and Transfusion, Birmingham, United Kingdom; 5Nephrology and Transplantation, University Hospitals Coventry and Warwickshire, Coventry, United Kingdom; 6Nephrology and Transplantation, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Introduction: Complement fixing donor specific antibodies (DSA) as detected by presence of C3d at the time of rejection is associated with poor graft outcome;no studies…
  • 2017 American Transplant Congress

    Post Transplant Outcomes in Hepatitis C Positive Patients.

    M. Lubetzky, N. Hayde, L. Kamal, M. Ajaimy, P. Bedi, G. Deboccardo, J. Rocca, S. Greenstein, J. Graham, A. Chokechanachaisakul, A. Courson, M. Kinkhabwala, E. Akalin.

    Montefiore Medical Center, Bronx

    Hepatitis C (HCV) is associated with increased morbidity and mortality after kidney transplant (KTx). We aimed to assess outcomes of HCV positive patients at our…
  • 2017 American Transplant Congress

    Vascularized Bone Marrow Mechanisms of Immunomodulation.

    A. Khalifeh, E. Buckingham, M. Uluer, W. Hassanein, W. Twaddell, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.

    University of Maryland School of Medicine, Baltimore, MD

    Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…
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