Articles tagged "Graft survival"

2017 American Transplant Congress
Long-Term Outcomes of Kidney Transplant Recipients with Primary Idiopathic Focal Segmental Glomerulosclerosis (FSGS).
D. Khadzhynov, F. Halleck, L. Lehner, E. Schrezenmeier, K. Budde, O. Staeck.
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction:Few data exists analyzing recurrence rates, treatment response and long-term outcomes in kidney transplant recipients (KTR) with primary FSGS.Methods: This retrospective observational study included 1218…
2017 American Transplant Congress
A Nationwide Global Strategy for Kidney Transplantation with Controlled Cardiac Death Donor (cDCD) Has Improved Global Results. Spanish Multicentre SENTRA-GEODAS Group.
J. Portoles,^1,2 M. Perez-Saez,^2,3 D. Janeiro,^1,2 E. Melilli,² N. Maruri Kareaga,² E. de Souza,² F. Llamas,² J. Espi,² P. Martin Moreno,² D. Navarro,² A. Sancho-Calabuig,² M. Rodriguez-Ferrero,² D. Hernandez,² J. Pascual.^2,3
¹Nephrology, Hospital Puerta de Hierro, Majadahonda, Spain; ²GEODAS-SENTRA Public Health Research Net RedinRen16/009/009 RETYC ISCIII, Madrid, Spain; ³Nephrology, Hospital del Mar, Barcelona, Spain
Background: Controlled donation after cardiac death (cDCD) programs are running in US for years and some European countries has recently started on it. National transplant…
2017 American Transplant Congress
HLA Mismatching Does Not Have an Impact on Graft or Patient Survival in Simultaneous Kidney-Pancreas Transplantation. A Single Institution Experience.
I. Moinuddin, M. Yaqub, T. Taber, D. Mishler, M. Mujtaba, J. Powelson, O. Adebiyi, J. Fridell, A. Sharfuddin.
Indiana University Health, Indianapolis
Purpose: There is conflicting data on whether the level and type of HLA mismatching (MM) has an impact on pancreas, kidney, or patient survival in…
2017 American Transplant Congress
Propensity-Matched Comparison of Diabetic Patients and Non-Diabetic Patients in Living Donor Kidney Transplantation.
C. Baek,¹ H. Kim,¹ W. Yang,¹ D. Han,² S.-K. Park.¹
¹Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; ²Department of Surgery, Asan Medical Center, Seoul, Republic of Korea
Background: Kidney transplantation (KT) reportedly provides a significant survival advantage over dialysis in diabetic patients. However, KT outcome in diabetic patients compared with that in…
2017 American Transplant Congress
Impact of Non-Adherence in a Cohort of Kidney Transplant Recipients.
M. Merino-López,¹ C. Flores-Gama.²
¹National Autonomous University of Mexico, Mexico, Mexico; ²Nephrology, National Institute of Cardiology, Mexico, Mexico
Background: The understanding of the main causes of allograft losts and related factors is a critical in the sucess of kidney transplantation programs.Objective: The aim…
2017 American Transplant Congress
The Gut Microbiota Regulates Murine Cardiac Transplant Outcome.
Y. Xiong, C. Brinkman, L. Hittle, W. Fricke, E. Mongodin, J. Bromberg.
UMB, Baltimore
Background: Gut microbiota regulates systemic immunity and can activate pro- or anti-inflammatory pathways. We hypothesized that the gut microbiota influences the survival of mismatched murine…
2017 American Transplant Congress
Combination αCD28+αCD40 Costimulation Blockade Attenuates Acute and Chronic Rejection in Non-Human Primates.
N. O'Neill, T. Zhang, W. Sun, G. Braileanu, X. Cheng, I. Tatarov, W. Hassanein, A. Azimzadeh, R. Pierson.
University of Maryland School of Medicine, Baltimore, MD
Purpose: Monotherapy using αCD28 or αCD40 antibodies significantly prolongs graft survival but does not induce tolerance in non-human primates (NHP). Here, we evaluate the relative…
2017 American Transplant Congress
Donor Age Is the Most Important Predictor of Longterm Graft Function in Simultaneous Pancreas-Kidney Transplantation from Donors After Cardiac Death.
J. Chen,¹ D. Mikhail,^1,2 H. Sharma,³ A. Hijazi,¹ D. Nap,¹ L. Stitt,⁴ J. Jevnikar,⁵ M. Cooper,⁶ P. Luke,^1,2 A. Sener.^1,2
¹Schulich School of Medicine and Dentistry, London, Canada; ²Division of Urology, Department of Surgery, Western University, London, London, Canada; ³Division of General Surgery, Department of Urology, Western University, London, Canada; ⁴LW Stitt Statistical Services, London, Canada; ⁵Faculty of Engineering and Architectural Sciences, Ryerson University, Toronto, Canada; ⁶Georgetown University, Washington
STUDY PURPOSE: We analyzed data from UNOS to determine the effects of donor age, donor BMI, and organ cold ischemic time on DCD-SPK graft outcomes.METHODS:…
2017 American Transplant Congress
The Role of Toll-Like Receptor 4 in Islet Transplantation and a Novel Method of Protection Using Chemical Surface Modification.
C. Chang,¹ G. Yoshimatsu,² B. Akinbobuyi,⁴ M. Lawrence,² R. Kane,¹ B. Naziruddin.³
¹Institute of Biomedical Studies, Baylor University, Waco, TX; ²Baylor Scott and White Research Institute, Dallas, TX; ³Baylor Simmons Transplant Institute, Dallas, TX; ⁴Department of Chemistry and Biochemistry, Baylor University, Waco, TX
Toll-like Receptor 4 (TLR4) is the canonical receptor for lipopolysaccharide (LPS), however recent evidence reveals that TLR4 also plays an important role in ischemia-reperfusion injury…
2017 American Transplant Congress
Medicinal Herb Cordyceps Sinensis Promotes Long-Term Allograft Survival by Tipping the Balance Between CD4+FoxP3+ Tregs and CD8+ Tcm Cells.
Z. Dai,¹ H. Dai.²
¹Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China; ²University of Pittsburgh, Pittsburgh, PA
Achieving long-term allograft survival or tolerance without continuously global immunosuppression is highly desirable in transplantation. This study was set to induce long-term allograft survival using…