ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    Rapid Deterioration of Pre-Transplant Kidney Function Requiring Dialysis Is a Prognostic Factor in Liver Transplant Alone.

    S. Nagai,1 M. Safwan,1 K. Collins,1 M. Rizzari,1 D. Moonka,2 A. Patel,3 K. Brown,2 A. Yoshida,1 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI; 3Nephrology, Henry Ford Hospital, Detroit, MI

    Aim: Etiologies of acute kidney injury before liver transplant extend beyond hepatorenal syndrome (ie infection, gastrointestinal bleeding) and therefore, may not be resolved by liver…
  • 2017 American Transplant Congress

    Assessment of the Risk Index for Living Donor Kidney Transplantation (LKDPI) in a European Cohort.

    O. Staeck, G. Rehse, D. Khadzhynov, A. Kleinsteuber, L. Lehner, M. Duerr, K. Budde, F. Halleck.

    Nephrology, Charité Universitaetsmedizin, Berlin, Germany

    Introduction: Recently, a risk index for living donor kidney transplantation (LKDPI) was proposed (Massie et al. AJT 2016) to compare living donor kidneys (LDK) to…
  • 2017 American Transplant Congress

    The Use of Very High KDPI Kidneys in Elderly Kidney Transplant Recipients – Discarded in the U.S. but Successfully Transplanted in Europe.

    F. Halleck, D. Khadzhynov, G. Rehse, L. Lehner, E. Schrezenmeier, M. Dürr, K. Budde, O. Staeck.

    Nephrology, Charité Berlin, Berlin, Germany

    Background: Very limited data exist on long-term outcomes of very high KDPI kidneys in elderly (≥65 years) kidney transplant recipients (KTR). Discard rates of donor…
  • 2017 American Transplant Congress

    Donor Recipient Matching Based on HLA Epitopes Improves Outcome in Kidney Transplant Recipients.

    O. Staeck,1 M. Niemann,3 F. Halleck,1 D. Khadzhynov,1 C. Schönemann,2 P. Reinke,1 E. Spierings,4 K. Budde,1 N. Lachmann.2

    1Nephrology, Charité Universitaetsmedizin, Berlin, Germany; 2HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; 3PIRCHE, Berlin, Germany; 4Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands

    Background: HLA mismatches of the donor and recipient causing de novo donor-specific HLA antibodies (dnDSA) are a risk factor for immunologic complications and poor graft…
  • 2017 American Transplant Congress

    Twenty Year Trends in Outcomes and Costs Following Kidney Transplantation.

    A. Ojo,1 N. Agashivala,2 L. Gache,3 W. Irish.3

    1University of Arizona Health Sciences, Phoenix, AZ; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ; 3CTI Clinical Trial and Consulting Services, Inc., Cincinnati, OH

    Purpose. Short term outcomes of kidney transplantation (KTx) are excellent, but it is unclear that long term outcomes have improved, despite advances in immunosuppression (IS).…
  • 2017 American Transplant Congress

    Comparison of Locoregional Therapies for Hepatocellular Carcinoma in Liver Transplant Recipients.

    M. Chen, B. Philosophe.

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Background: Locoregional therapies (LRT) have been employed in patients with hepatocellular carcinoma (HCC) to halt tumor progression and prevent waitlist drop out, as well as…
  • 2017 American Transplant Congress

    Alemtuzumab Induction Is Associated with a Lower Incidence of BK Virus Nephropathy Compared with IL2RA Induction.

    A. Gueret-Wardle, S. Hassan, G. Lucisano, C. Roufosse, M. Willicombe, D. Taube.

    Renal Medicine, West London Renal and Transplant Centre, London, United Kingdom

    Introduction:BK polyoma virus associated nephropathy [BKVAN] is a major cause of allograft dysfunction and graft loss occurring in up to 10% of kidney allograft recipients…
  • 2017 American Transplant Congress

    Second-Line Therapy After Standard of Care in Antibody-Mediated Rejection: A Prospective Study.

    D. Viglietti, A. Loupy, O. Aubert, E. Pillebout, C. Legendre, D. Glotz, C. Lefaucheur.

    Paris Translational Research Center for Organ Transplantation, Paris, France

    There is a marked heterogeneity in AMR patients' prognosis after SOC treatment including plasma exchange (PE) and intravenous immunoglobulins (IVIG). We investigated whether a composite…
  • 2017 American Transplant Congress

    Is the Time of Appearance and Resolution of De Novo HLA-DP Donor Specific Antibodies Associated with Reduced Deleterious Effect on Lung Transplant Outcomes?

    A. Zhang,1 Y. Sun,2 K. McCurry,3 M. Budev.3

    1Allogen Laboratories, Cleveland Clinic, Cleveland, OH; 2Avalon University School of Medicine, Willemstad, Netherlands Antilles; 3Transplantation Center, Cleveland Clinic, Cleveland, OH

    Introduction: The impact of HLA-DP de novo donor specific antibodies (dDSA) to lung transplantation (LT) is poorly understood. This study analyzed the association of timely…
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