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American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Desensitization versus Deceased Donor Kidney Transplantation: What to Choose When Both Become Available?

    B. Orandi,1 X. Luo,2 J. Garonzik-Wang,2 R. Montgomery,3 D. Segev.2

    1UCSF, San Francisco; 2Johns Hopkins, Baltimore; 3NYU, New York

    Kidney allocation system changes have improved deceased donor kidney transplant (DDKT) access for highly sensitized patients. For patients with a willing live donor but requiring…
  • 2017 American Transplant Congress

    Provision of Highly Specialized Aftercare by the Transplant Center Strongly Improves Patient and Allograft Survival in Long-Term Follow-Up After Kidney Transplantation.

    T. Schachtner,1,2,3 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; 3Berlin Institute of Health BIH, Berlin, Germany

    Despite rapid medical advancements in the field of transplantation, mean kidney allograft survival remained at a standstill. If and to what extent a highly specialized…
  • 2017 American Transplant Congress

    Lymphotoxin (LT) β Receptor-Mediated Non-Classical NFκB Signaling in Lymphatic Endothelial Eells (LEC) is Required for Homeostatic T Cell Migration.

    W. Piao, C. Brinkman, J. Bromberg.

    UMB, Baltimore

    Background: The selective recruitment of regulatory T cells (Treg) or blockade of memory/effector T cell migration to the graft and draining lymph nodes (dLN) are…
  • 2017 American Transplant Congress

    Impact of Belatacept Conversion on Kidney Transplant Function, Histology and Gene Expression.

    P. Sanghi,1 G. Gupta,1 D. Kumar,1 J. Reeve,2 M. Levy,1 A. Sharma,1 H. Fattah,1 P. Kimball,1 H. Massey,1 A. King,1 P. Halloran.2

    1Virginia Commonwealth University, Richmond; 2Alberta Transplant Applied Genomics Center, Edmonton, Canada

    Background: Belatacept (bela) might be an alternative to Calcineurin Inhibitors (CNI) in order to avoid presumed nephrotoxicity. In this study we assessed the impact of…
  • 2017 American Transplant Congress

    Accepting a High-KDPI Kidney versus Waiting for Another Offer Can Improve Chances of a Functioning Graft.

    A. Wey,1 N. Salkowski,1 W. Kremers,2 A. Israni,1 B. Kasiske,1 J. Snyder.1

    1Scientific Registry of Transplant Recipients, Minneapolis, MN; 2Mayo Clinic, Rochester, MN

    Less than 50% of waitlisted candidates undergo a first deceased donor transplant within 5 years. Yet approximately 20% of recovered kidneys and >50% of kidneys…
  • 2017 American Transplant Congress

    Benefits of Expanding Options for Patients Registered in the Kidney Paired Donation Program.

    S. Stepkowski, B. Mierzejewska, D. Belbolsynov, C. Baum, J. Kopke, R. Brunner, S. Rees, M. Rees.

    University of Toledo, Toledo, OH

    Introduction: Kidney Paired Donation (KPD) programs play an important role in facilitating exchanges of incompatible donors. We reviewed the outcome of 1121 patients who were…
  • 2017 American Transplant Congress

    Does HLA Class of Complement Activating Donor Specific Antibodies Matter: Single Centre Retrospective Analysis of Renal Allograft Outcomes.

    A. Babu,1,2,3 D. Briggs,3 D. Mitchell,1 N. Krishnan,2 R. Higgins,1 S. Daga.1,2,4

    1Warwick Medical School, University of Warwick, Coventry, United Kingdom; 2Nephrology and Transplantation, University Hospitals Coventrya and Warwickshire, Coventry, United Kingdom; 3Histocompatibility and Immunogenetics, NHS Blood and Transfusion, Birmingham, United Kingdom; 4Nephrology and Transplantation, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Introduction. Complement activating donor specific antibodies may be associated with worse outcomes in a cohort of patients who have undergone HLA-AIT. We looked for differences…
  • 2017 American Transplant Congress

    A Clinically Relevant Protocol for Vascularized Composite Allotransplantation Using a Single Dose of AMD3100 for Stem Cell Mobilization.

    B. Swearingen,1,2 S. Graves,2,3 R. Storb,2,3 D. Mathes.1,2

    1Surgery, Division of Plastic and Reconstructive Surgery, University of Colorado School of Medicine, Aurora, CO; 2Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; 3Medicine, University of Washington Medical Center, Seattle, WA

    BACKGROUND: Vascularized Composite Allograft (VCA) transplantation is a clinical reality but application is limited by toxicities of chronic immunosuppression and rejection. Current clinical tolerance protocols…
  • 2017 American Transplant Congress

    Status 1 Liver Transplantation: Changes in Characteristics and Outcome Over Time.

    H. Truong, L. Lacar, L. Wong.

    General Surgery, University of Hawaii, JABSOM, Honolulu, HI

    Purpose: Approximately 5% of liver transplants (LT) annually require this urgently as “Status 1." The aim of this study is to characterize patients who received…
  • 2017 American Transplant Congress

    The Efficacy and Safety of Plaquenil in Kidney Transplants Patients with Lupus.

    S. Rhazouani,1,4 S. Anwar,2 D. Brennan,1 K. Lentine,3 K. Venkatachalam,1 A. Malone,1 T. Alhamad.1

    1Washington University, Saint Louis; 2Freman Hospital, New Castle, United Kingdom; 3Saint Louis University, Saint Louis; 4Cleveland Clinic Foundation, Weston

    Background: Hydroxychloroquine, also known as Plaquenil ( PLQ) is an antimalarial drug with immunomodulatory action. Recent studies have demonstrated a protective effect of PLQ in…
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