2017 American Transplant Congress
Lymphotoxin (LT) β Receptor-Mediated Non-Classical NFκB Signaling in Lymphatic Endothelial Eells (LEC) is Required for Homeostatic T Cell Migration.
Background: The selective recruitment of regulatory T cells (Treg) or blockade of memory/effector T cell migration to the graft and draining lymph nodes (dLN) are…2017 American Transplant Congress
Impact of Belatacept Conversion on Kidney Transplant Function, Histology and Gene Expression.
Background: Belatacept (bela) might be an alternative to Calcineurin Inhibitors (CNI) in order to avoid presumed nephrotoxicity. In this study we assessed the impact of…2017 American Transplant Congress
Accepting a High-KDPI Kidney versus Waiting for Another Offer Can Improve Chances of a Functioning Graft.
1Scientific Registry of Transplant Recipients, Minneapolis, MN; 2Mayo Clinic, Rochester, MN
Less than 50% of waitlisted candidates undergo a first deceased donor transplant within 5 years. Yet approximately 20% of recovered kidneys and >50% of kidneys…2017 American Transplant Congress
Benefits of Expanding Options for Patients Registered in the Kidney Paired Donation Program.
University of Toledo, Toledo, OH
Introduction: Kidney Paired Donation (KPD) programs play an important role in facilitating exchanges of incompatible donors. We reviewed the outcome of 1121 patients who were…2017 American Transplant Congress
Does HLA Class of Complement Activating Donor Specific Antibodies Matter: Single Centre Retrospective Analysis of Renal Allograft Outcomes.
Introduction. Complement activating donor specific antibodies may be associated with worse outcomes in a cohort of patients who have undergone HLA-AIT. We looked for differences…2017 American Transplant Congress
A Clinically Relevant Protocol for Vascularized Composite Allotransplantation Using a Single Dose of AMD3100 for Stem Cell Mobilization.
BACKGROUND: Vascularized Composite Allograft (VCA) transplantation is a clinical reality but application is limited by toxicities of chronic immunosuppression and rejection. Current clinical tolerance protocols…2017 American Transplant Congress
Status 1 Liver Transplantation: Changes in Characteristics and Outcome Over Time.
General Surgery, University of Hawaii, JABSOM, Honolulu, HI
Purpose: Approximately 5% of liver transplants (LT) annually require this urgently as “Status 1." The aim of this study is to characterize patients who received…2017 American Transplant Congress
The Efficacy and Safety of Plaquenil in Kidney Transplants Patients with Lupus.
Background: Hydroxychloroquine, also known as Plaquenil ( PLQ) is an antimalarial drug with immunomodulatory action. Recent studies have demonstrated a protective effect of PLQ in…2017 American Transplant Congress
Predictors of Graft Loss in an Urban Predominantly Minority Cohort of Kidney Transplant Recipients.
Monterfiore/Einstein Center for Transplantation, Bronx, NY
BackgroundWe aimed to determine the demographic and clinical characteristics associated with graft loss in a cohort of kidney transplant recipients with a high African-American and…2017 American Transplant Congress
Reduction of Recipient Cell Cross-Dressing with Donor MHC Molecules Prolongs Allograft Survival in Mice.
Cross-dressing of recipient cells with allogeneic MHC molecules carried by donor exosomes occurs regularly after transplantation. However, it is still unknown whether this phenomenon plays…
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