ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2017 American Transplant Congress

    Role of HMG CoA Reductase Inhibitors on Time to Development of Chronic Lung Allograft Dysfunction Post-Lung Transplant.

    A. Szczepanik, A. Hulbert, H. Lee, C. Benedetti, L. Snyder, J. Byrns.

    Duke University Hospital, Durham, NC

    Purpose: Five-year survival after lung transplant (LT) is approximately 55%. Chronic lung allograft dysfunction (CLAD) is a primary contributor to this reduced survival post-LT. Options…
  • 2017 American Transplant Congress

    Subpopulations of Peripheral Blood Monocytes in Kidney Allograft Recipients.

    I. Striz,1 V. Svachova,1 A. Sekerkova,1 J. Slatinska,2 K. Kopecka,1 M. Fialova,1 O. Viklicky.2

    1Department of Clinical and Transplant Immunology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic; 2Department of Nephrology, Transplant Centre, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic

    Human peripheral blood monocytes may be divided into different subsets based on the expression of membrane antigens. Our pilot data suggested that after the kidney…
  • 2017 American Transplant Congress

    Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.

    D. Cibrik,1 W. Irish,2 K. McCague,3 D. Patel,3 H. Tedesco.4

    1University of Michigan, Ann Arbor, MI; 2CTI Clinical Trial and Consulting Services, Raleigh, NC; 3Novartis Pharmaceuticals Corporation, East Hanover, NJ; 4Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil

    In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
  • 2017 American Transplant Congress

    Rapid Deterioration of Pre-Transplant Kidney Function Requiring Dialysis Is a Prognostic Factor in Liver Transplant Alone.

    S. Nagai,1 M. Safwan,1 K. Collins,1 M. Rizzari,1 D. Moonka,2 A. Patel,3 K. Brown,2 A. Yoshida,1 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Gastroenterology, Henry Ford Hospital, Detroit, MI; 3Nephrology, Henry Ford Hospital, Detroit, MI

    Aim: Etiologies of acute kidney injury before liver transplant extend beyond hepatorenal syndrome (ie infection, gastrointestinal bleeding) and therefore, may not be resolved by liver…
  • 2017 American Transplant Congress

    Assessment of the Risk Index for Living Donor Kidney Transplantation (LKDPI) in a European Cohort.

    O. Staeck, G. Rehse, D. Khadzhynov, A. Kleinsteuber, L. Lehner, M. Duerr, K. Budde, F. Halleck.

    Nephrology, Charité Universitaetsmedizin, Berlin, Germany

    Introduction: Recently, a risk index for living donor kidney transplantation (LKDPI) was proposed (Massie et al. AJT 2016) to compare living donor kidneys (LDK) to…
  • 2017 American Transplant Congress

    The Use of Very High KDPI Kidneys in Elderly Kidney Transplant Recipients – Discarded in the U.S. but Successfully Transplanted in Europe.

    F. Halleck, D. Khadzhynov, G. Rehse, L. Lehner, E. Schrezenmeier, M. Dürr, K. Budde, O. Staeck.

    Nephrology, Charité Berlin, Berlin, Germany

    Background: Very limited data exist on long-term outcomes of very high KDPI kidneys in elderly (≥65 years) kidney transplant recipients (KTR). Discard rates of donor…
  • 2017 American Transplant Congress

    Donor Recipient Matching Based on HLA Epitopes Improves Outcome in Kidney Transplant Recipients.

    O. Staeck,1 M. Niemann,3 F. Halleck,1 D. Khadzhynov,1 C. Schönemann,2 P. Reinke,1 E. Spierings,4 K. Budde,1 N. Lachmann.2

    1Nephrology, Charité Universitaetsmedizin, Berlin, Germany; 2HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; 3PIRCHE, Berlin, Germany; 4Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands

    Background: HLA mismatches of the donor and recipient causing de novo donor-specific HLA antibodies (dnDSA) are a risk factor for immunologic complications and poor graft…
  • 2017 American Transplant Congress

    Twenty Year Trends in Outcomes and Costs Following Kidney Transplantation.

    A. Ojo,1 N. Agashivala,2 L. Gache,3 W. Irish.3

    1University of Arizona Health Sciences, Phoenix, AZ; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ; 3CTI Clinical Trial and Consulting Services, Inc., Cincinnati, OH

    Purpose. Short term outcomes of kidney transplantation (KTx) are excellent, but it is unclear that long term outcomes have improved, despite advances in immunosuppression (IS).…
  • 2017 American Transplant Congress

    Comparison of Locoregional Therapies for Hepatocellular Carcinoma in Liver Transplant Recipients.

    M. Chen, B. Philosophe.

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Background: Locoregional therapies (LRT) have been employed in patients with hepatocellular carcinoma (HCC) to halt tumor progression and prevent waitlist drop out, as well as…
  • 2017 American Transplant Congress

    Alemtuzumab Induction Is Associated with a Lower Incidence of BK Virus Nephropathy Compared with IL2RA Induction.

    A. Gueret-Wardle, S. Hassan, G. Lucisano, C. Roufosse, M. Willicombe, D. Taube.

    Renal Medicine, West London Renal and Transplant Centre, London, United Kingdom

    Introduction:BK polyoma virus associated nephropathy [BKVAN] is a major cause of allograft dysfunction and graft loss occurring in up to 10% of kidney allograft recipients…
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