2018 American Transplant Congress
MERTK Mediates Transplant Tolerance via IFN-a Regulation of MDSCs and Tregs
Northwestern University Feinberg School of Medicine, Chicago.
Introduction: MERTK is one of the TAM receptor tyrosine kinases (RTKs) that mediate homeostatic phagocytosis of apoptotic cells, and transmit regulatory signals that modulate immune…2018 American Transplant Congress
Liver Transplant Survival Index for Recipients with High MELD Score: A Model for Post-Transplant Survival in Severely Ill Patients
Background: SHARE-35 prioritizes patients with MELD scores ≥35 for regional sharing of liver allografts. Because this policy incentivizes transplantation of sicker patients, this study examines…2018 American Transplant Congress
Using the SRTR Expected Survival Worksheet to Estimate Expected Number of Events
The purpose of this effort is to provide transplant administrative and clinical directors with reliable predictions of Scientific Registry of Transplant Recipients (SRTR) risk-adjusted 1-year…2018 American Transplant Congress
When Does Donor Age Matter? A Review of over 70,000 Liver Transplants
Surgery, Baylor College of Medicine, Houston, TX.
Background: Past studies on donor age in liver transplantation have largely relied on binary groups (i.e., young vs. old) with arbitrarily defined cut-offs. The aim…2018 American Transplant Congress
State of the Union: Outcomes of a Single Center's A2-to-B Transplants Two Years after the Implementation of KAS
Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.
Introduction. Since the implementation of the new KAS there are few reports on both single center outcomes in the modern era of transplantation and the…2018 American Transplant Congress
Biochemistry Profiles Following Pig-to-Nonhuman Primate Liver Xenotransplantation
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Objectives:Clinical progress in liver transplantation has increased the demand for organs, however, supply remains stagnant. Porcine liver xenotransplantation (LXT) would help address this imbalance. Here…2018 American Transplant Congress
Enhanced Recovery after Kidney Transplantation Regardless of Donor Organ Source
BACKGROUND: Enhanced recovery after kidney transplantation is a desired outcome with potential value-enhancing benefits of reduced length of stay (LOS), costs, and risk of nosocomial…2018 American Transplant Congress
Malignancies in Kidney Transplant Recipients: A Long-Term Observational Study
Nephrology and Internal Intensive Care, Charite Universitaetsmedizin Berlin, Berlin, Germany.
Background: Previous studies have shown increased incidence of malignancies in patients after kidney transplantation. However, most of the existing data on post-transplant malignancies is limited…2018 American Transplant Congress
Subclinical Borderline Rejection: More Than Meets the Eye?
UAB School of Medicine, Birmingham.
Purpose: Surveillance biopsies can detect subclinical T cell mediated rejection (SC-TCMR) or subclinical borderline rejection (SC-B-TCMR) in patients with normal/stable creatinine, but the impact on…2018 American Transplant Congress
VLA-4 Blockade Inhibits Early Endogenous Memory CD8 T Cell Infiltration into Higher Risk Cardiac Allografts and Donor-Reactive T Cell Priming
Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts within 24 hrs after graft reperfusion in mice. Our recent studies indicate that prolonged cold ischemic…
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