Articles tagged "Graft survival"

2018 American Transplant Congress
LDLT for High MELD Recipients: A Single Center Experience
S. Ganesh, M. Molinari, T. Amit, H. Christopher, H. Abhinav.
Surgery, University of Pittsburgh, Pittsburgh, PA.
Objectives: Living donor liver transplantation (LDLT) is underutilized in high MELD patients. Our aim was to assess the impact of high MELD score on short-term…
2018 American Transplant Congress
Mid-Term Outcome of Donor Specific Antibody Positive Deceased Donor Kidney Transplantation with Peri-Transplant Desensitization
K. Osickova,¹ P. Hruba,² J. Slatinska,¹ A. Slavcev,² J. Fronek,² E. Honsova,² O. Viklicky.¹
¹Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; ²Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Donor specific HLA-antibodies (DSA) remain a large barrier to successful kidney transplantation and there is a limited knowledge about desensitization strategies in deceased donor programs.Anti…
2018 American Transplant Congress
High Fibre Diet Induces Donor Specific Kidney Allograft Tolerance in Mice
H. Wu,^1,2 T. Kwan,² Y. Loh,² C. Wang,² L. Macia,² S. Alexander,^2,3 S. Chadban.^1,2
¹Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; ²University of Sydney, Sydney, Australia; ³The Children Hospital at Westmead, Sydney, Australia.
Aim: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid sodium acetate (SA) on kidney allograft…
2018 American Transplant Congress
Intraoperative Blood Loss during Pediatric Liver Transplantation: A Single Center Experience
J. Kohler,¹ D. Yoeli,¹ R. Sigireddi,¹ R. Ackah,¹ M. Kueht,² T. Galvan,² R. Cotton,² A. Rana,² C. O'Mahony,² J. Goss.²
¹School of Medicine, Baylor College of Medicine, Houston, TX; ²Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Background: The aim of this study is to identify risk factors for massive intraoperative blood loss in pediatric liver transplant recipients and describe its impact…
2018 American Transplant Congress
Sirolimus-Based, Prednisone-Free Regimen in Kidney Transplantation: Long Term Results of an Open-Label, Randomized Controlled Trial
A. Shetty,¹ B. Ho,¹ V. Mas,² Y. Kassis,¹ S. Park,¹ J. Leventhal,¹ D. Chhabra,³ L. Gallon.¹
¹Northwestern University, Chicago; ²University of Virginia, Charlottesville; ³Advocate Christ Medical Center, Chicago.
Background: Calcineurin (CNI) nephrotoxicity is implicated in chronic allograft dysfunction and presents an argument for CNI minimizing immunosuppression. We assessed the long-term effects of CNI…
2018 American Transplant Congress
Graft Immunocomplex Capture Fluorescence Analysis Can Detect Intra-Graft Anti-Blood Group A/B Antibodies
T. Nakamura,¹ H. Ushigome,¹ Y. Imanishi,² S. Kawai,³ T. Shirouzu,³ M. Osaka,¹ K. Masuda,¹ T. Matsuyama,¹ S. Harada,¹ S. Nobori,¹ N. Yoshimura.¹
¹Department of Organ Transplantation and General Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan; ²Department of Blood Transfusion and Cell Therapy, Kyoto Prefectural University of Medicine, Kyoto, Japan; ³Molecular Diagnostics Division, Wakunaga Pharmaceutical Co., Led, Hiroshima, Japan.
Background: Graft immunocomplex capture fluorescence analysis (ICFA) is an attractive method to detect intra-graft donor-specific anti-HLA antibodies (HLA-DSA). In ABO incompatible (ABOi) transplantation, anti-A/B antibodies…
2018 American Transplant Congress
Using the Remuzzi Score to Guide Single vs. Dual Transplantation Mitigates the Risk of Early Graft Failure
J. Ayorinde, G. Pettigrew.
Surgery, University of Cambridge, Cambridge, United Kingdom.
BackgroundExpanded criteria circulatory death donors (DCD) may represent an underutilised donor pool. Our centre has used urgent pre-implantation biopsy (Remuzzi score) to guide single (SKT)…
2018 American Transplant Congress
Donor Deficiency of RIP3 Phosphokinase Activity Shortens Cardiac Allograft Survival in the Setting of Costimulation Blockade
M. Zhu, K. Samy, L. Lin, J. Wang, L. Cendales, A. Kirk, A. Barbas, T. Brennan.
Surgery, Duke University, Durham, NC.
Receptor-interacting protein kinase 3 (RIP3) is critical for necroptosis in the setting of inflammation. It has been shown that kidney and heart allografts deficient in…
2018 American Transplant Congress
The Impact of Early versus Late Clinical Outcomes on Disparities in African-American Kidney Transplant Recipients
D. Taber, J. Fleming, Z. Su, P. Mauldin, J. McGillicuddy, S. Nadig, V. Rohan, P. Baliga, D. Dubay.
MUSC, Charleston, SC.
Background: It is important to better understand the impact of early and late clinical events on disparities in African-American (AA) kidney transplant (KTX), which will…
2018 American Transplant Congress
Long Term Outcomes of Renal Allografts with De Novo DSA in the Setting of Stable Graft Function versus Acute Rejection
R. Knight,¹ D. Nguyen,² E. Graviss,² T. Eagar,² S. Kuten,³ S. Patel,³ L. Moore,¹ A. Gaber.¹
¹Surgery, Houston Methodist Hospital, Houston, TX; ²Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX; ³Pharmacy, Houston Methodist, Houston, TX.
We sought to compare the long-term outcome of renal allograft recipients with de novo DSA (dnDSA) in the setting of stable allograft function versus dnDSA…