Articles tagged "Graft survival"

2018 American Transplant Congress
As Clear as Mud: Volatility of the Five-Tier Quality Assessment of Kidney Transplant Centers in the United States
J. Schold,¹ K. Andreoni,² A. Chandraker,³ R. Gaston,⁴ J. Locke,⁴ A. Mathur,⁵ T. Pruett,⁶ A. Rana,⁷ L. Ratner,⁸ L. Buccini.¹
¹Cleveland Clinic, Cleveland; ²University of Florida, Gainesville; ³Harvard Medical School, Boston; ⁴University of Alabama at Birmingham, Birmingham; ⁵Mayo Clinic, Phoenix; ⁶University of Minnesota, Minneapolis; ⁷Baylor College of Medicine, Houston; ⁸Columbia University, New York.
Outcomes of patients receiving transplants in the US are systematically aggregated into bi-annual Program-Specific Reports(PSRs) detailing risk-adjusted survival by transplant center. Recently the SRTR issued…
2018 American Transplant Congress
Dunbar Syndrome in Liver Transplantation: Results of a Single Center Matched-Pair Analysis and a European Survey Study
D. Morales-Santana,¹ Z. Czigany,¹ J. Böcker,¹ A. Andert,¹ W. Schöning,¹ T. Ulmer,¹ J. Bednarsch,¹ I. Amygdalos,¹ F. Meister,¹ P. Isfort,³ M. Liebl,³ D. Kroy,² F. Tacke,² C. Trautwein,² U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Internal Medicine III, University Hospital RWTH, Aachen, Germany; ³Institute of Radiology, University Hospital RWTH, Aachen, Germany.
Background: Median-arcuate-ligament or Dunbar-syndrome (MALs) potentially causes arterial complications in orthotopic liver transplantation (OLT). This study aimed to investigate MALs incidence and its impact on…
2018 American Transplant Congress
One-Year Graft Survival for Longevity Matched Kidneys in the Post-KAS Era
A. Wilk,¹ M. Aeder,² V. Casingal,³ N. Turgeon.⁴
¹United Network for Organ Sharing, Richmond, VA; ²University Hospitals Cleveland Medical Center, Cleveland, OH; ³Carolina's Healthcare, Charlotte, NC; ⁴Emory University, Atlanta, GA.
One of the key goals and achievements of KAS was to make better use of available kidneys by improving longevity matching between donor kidneys and…
2018 American Transplant Congress
Predicting Outcomes of Rat Vascularized Composite Allotransplants through Quantitative Measurement of Chimerism with PCR-Amplified Short Tandem Repeat
H. Cheng,¹ X. Huang,² C-.F. Lin,¹ N. AL Deek,² L. Shih,² C-.H. Lin,^1,2 F-.C. Wei.^1,2,3
¹Center for Vascularized Composite Allotransplantation, Linkou Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ²Department of Plastic and Reconstructive Surgery, Linkou Chang Gung Memorial Hospital, Gueishan, Taoyuan, Taiwan; ³College of Medicine, Chang Gung University, Gueishan, Taoyuan, Taiwan.
Background: Chimerism, defined as coexistence of donor and recipient cells, has been associated with induction and maintenance of tolerance to allotransplants. Although most studies have…
2018 American Transplant Congress
Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study
Y. Kim,¹ Y. Chiang,² S. Kim,³ M. Kim,⁴ S. Park,⁵ S. Wu,⁶ K. Horita,⁷ Y. Nakashima,⁷ H. Jiang,⁸ D. Han.¹
¹Asan Medical Center, Seoul, Korea; ²Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; ³Samsung Medical Center, Seoul, Korea; ⁴Severance Hospital, Seoul, Korea; ⁵Dongsan Medical Center, Daegu, Korea; ⁶Tri-Service General Hospital, Taipei City, Taiwan; ⁷Astellas Pharma, Inc., Tokyo, Japan; ⁸Astellas Pharma, Inc., Maao, Singapore.
A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
2018 American Transplant Congress
Impact of Aberrant Post-Transplant Laboratory and Blood Pressure Values on Graft Survival and Racial Disparities in Kidney Transplant
D. Taber, Z. Su, J. Fleming, N. Pilch, A. Posadas, V. Rao, P. Mauldin, D. Dubay.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess the impact of post-transplant lab and blood pressure (BP) clinical data on graft survival and racial…
2018 American Transplant Congress
Klotho, HMGB-1 and Kynurenine as Marker for Injury and Function in Renal Transplantation
M. Stangl,¹ D. Abendroth.²
¹Transplant Center Munich, Klinikum Großhadern, LMU Munich, Munich, Germany; ²Surgery, University of Ulm, Ulm, Germany.
Brain death is associated with immune activation and tissue injuries, counter regulated by activation of the tryptophan pathway producing kynurenine (Kyn). High mobility group box…
2018 American Transplant Congress
Comparison of Induction and Maintenance Immunosuppression Regimens in Intestinal and Multivisceral Transplantation: An Analysis of the UNOS Registry
S. Nagai,¹ M. Rizzari,¹ Y. Muszkat,² K. Collins,¹ A. Yoshida,¹ S-.M. Jafri,² M. Abouljoud.¹
¹Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; ²Gastroenterology, Henry Ford Hospital, Detroit, MI.
Aim: Induction and maintenance immunosuppression regimens in intestinal transplant widely vary among centers. The aim of this study was to investigate an association between immunosuppression…
2018 American Transplant Congress
CMV Mismatch Still Negatively Affects Patient and Graft Survival in the Era of CMV Prophylactic and Preemptive Therapy: A Paired Kidney Analysis
N. Leeaphorn,¹ N. Garg,² N. Thamcharoen,¹ E. Khankin,¹ F. Cardarelli,¹ M. Pavlakis.¹
¹Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; ²Department of Medicine, Nephrology Division, University of Wisconsin School of Medicine, Madison, WI.
Background: The impact of CMV serostatus on kidney transplant outcomes in an era when CMV prophylactic and preemptive strategies are used routinely is not clearly…
2018 American Transplant Congress
Mechanisms of Vascularized Bone Marrow Graft Protection of Vascularized Composite Allografts
E. Buckingham, N. Shockcor, W. Hassanein, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.
Surgery, University of Maryland, Baltimore, MD.
Background Co-transplantation of vascularized bone marrow (VBM) promotes vascularized composite allograft (VCA) survival with standard immunosuppression in a non-human primate (NHP) model. We investigated mechanisms…