Articles tagged "Graft survival"

2018 American Transplant Congress
Rejection and Graft Loss in Patients with BK Viremia after Simultaneous Pancreas and Kidney Transplant
D. Keys, S. Riad, V. Vakil, S. Jackson, D. Berglund, A. Matas, R. Kandaswamy.
University of Minnesota, Minneapolis, MN.
Background: BK virus is a recognized cause of kidney allograft dysfunction. The treatment of BK is immunosuppression reduction. This reduction in patients with a simultaneous…
2018 American Transplant Congress
Patient and Transplant Outcome in Infants Starting Renal Replacement Therapy before Two Years of Age
J. Hogan,^1,2,3 J. Harambat,⁴ E. Berard,⁵ C. Couchoud,³ M-.A. Macher.^2,3
¹Pediatric Nephrology, Emory University, Atlanta, GA; ²Pediatric Nephrology, Robert Debre University Hospital, Paris, France; ³REIN Registry, French Biomedecine Agency, Paris, France; ⁴Pediatric Nephrology, Bordeaux University Hospital, Bordeaux, France; ⁵Pediatric Nephrology, L'archet Hospital, Nice, France.
Introduction: Despite major technical improvement in the care of children requiring renal replacement therapy (RRT) before two years of age, the management of those patients…
2018 American Transplant Congress
Excellent Long-Term Outcomes with Kidney Transplants from Deceased Donors with Acute Kidney Injury
G. Dube, S. Husain, D. Cohen, S. Mohan.
Medicine, Columbia University Medical Center, New York, NY.
Kidney transplants (KT) from donors with acute kidney injury (AKI; terminal creatinine ≥ 2.0) are increasingly performed and have similar short-term outcomes compared with KT…
2018 American Transplant Congress
Incidence of BK Viraemia and BK Virus Associated Nephropathy with Standard vs. Augmented Immunosuppression
R. Rathore, S. Anastassiadou, A. Kaur, J. Timms, N. Krishnan.
Renal Transplant, University Hospitals of Coventry and Warwickshire, Coventry, United Kingdom.
Introduction:It has been long established that over-immunosuppressed state leads to BK virus reactivation. BK viraemia (BKV) can progress to BK virus associated nephropathy (BKVAN) which…
2018 American Transplant Congress
Impact of De Novo DSA Development and Management on Kidney Transplant Outcomes
M. Cote,¹ M. Pavlakis,² F. Cardarelli,² J. Pena,³ A. Dinh,³ K. Richards,¹ K. Joyal,¹ C. Rogers.¹
¹Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA; ²Transplant Institute, Beth Israel Deaconess Medical Center, Boston, MA; ³Pathology, Beth Israel Deaconess Medical Center, Boston, MA.
Multiple studies have shown that development of donor specific antibodies (DSAs) can have a negative impact on renal allograft outcomes resulting in decreased renal function,…
2018 American Transplant Congress
Effect of Belatacept on Late Acute Rejection Episodes and Graft Loss in Young Adults between the Ages of 18-24 Years: Post-Hoc Analysis of BENEFIT Study
A. Moudgil.
Nephrology, Children National Health System, Washington, DC.
Background: Recent data suggests higher incidence of late acute rejection (LAR) in young adults (18-24 years of age) causing graft loss just like adolescents due…
2018 American Transplant Congress
Transplanting Kidneys from HCV-Infected Donors into HCV-Negative Recipients: Longer-Term and Extended Results of the THINKER Trial
D. Goldberg,¹ E. Blumberg,¹ P. Abt,¹ M. Levine,¹ P. Porrett,¹ A. Naji,¹ S. Nazarian,¹ D. Sawinski,¹ J. Trofe-Clark,¹ V. Van Deerlin,¹ C. Gentile,¹ J. Smith,¹ M. Kaminski,¹ A. Sicilia,¹ R. Hasz,² L. Suplee,² R. Reddy,¹ R. Bloom,¹ P. Reese.¹
¹University of Pennsylvania, Philadelphia; ²Gift of Life, Philadelphia.
Background: In 2016, 800 kidneys from HCV+ deceased donors were discarded. Short-term (6-month) data from the first 10 subjects in the THINKER-1 trial (NCT02743897; funder:…
2018 American Transplant Congress
Livers from Donation after Circulatory Death Donors Can Be Safely Used for Retransplantation
O. van Leeuwen,¹ M. van Reeven,² J. Erdmann,³ H. Metselaar,⁴ A. van den Berg,⁵ B. van Hoek,⁶ W. Polak,² R. Porte.¹
¹Department of Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Department of Surgery, Erasmus Medical Center, Rotterdam, Netherlands; ³Department of Surgery, Leiden University Medical Center, Leiden, Netherlands; ⁴Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, Netherlands; ⁵Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; ⁶Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: After donation after circulatory death (DCD) liver transplantation (LT), non-anastomotic biliary strictures (NAS) and early allograft dysfunction (EAD) are more frequently observed than after…
2018 American Transplant Congress
Should More Donation after Cardiac Death Livers Be Used in Pediatric Transplantation?
C. Hwang,¹ S. Levea,² M. MacConmara.¹
¹Surgery, UT Southwestern Medical Center, Dallas, TX; ²Medicine, UT Southwestern Medical Center, Dallas, TX.
Introduction: Multiple strategies exist to increase the organ pool for livers in pediatric recipients, including using split livers, high risk livers, and donation after cardiac…
2018 American Transplant Congress
Urinary C5b-9 is an Independent Predictor of Graft Failure in Renal Transplant Recipients
R. Lammerts, M. Eisenga, M. Alyami, M. Seelen, M. Daha, J. van den Born, S. Bakker, S. Berger, On behalf of the COMBAT Comsortium.
Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.
IntroductionChronic antibody-mediated rejection is thought to be the main cause of late kidney-allograft loss, involving donor-specific antibody–mediated activation of the complement system. Activation of filtered…