2019 American Transplant Congress
Allograft Survival is Influenced by Gut Microbiota-Dependent Modulation of Innate Immunity
*Purpose: The gut microbiota driven inflammatory response and the host immune system engage bidirectional regulation of each other. These interactions are poorly characterized in organ…2018 American Transplant Congress
Delayed Graft Function in Simultaneous Liver Kidney Transplantation
Purpose: Increased rates of delayed graft function (DGF) after simultaneous liver kidney (SLK) transplantation have been described, as well as inferior graft survival in patients…2018 American Transplant Congress
Individualized Immunosuppression through Risk-Stratification in Renal Transplantation Preserves Excellent Outcomes at Three Years
University of Virginia Health System, Charlottesville, VA.
Risk-stratification of renal transplant recipients based on immunologic risk factors allows for tailored immunosuppression (IS), but long term follow up is limited. This study evaluates…2018 American Transplant Congress
Identification of Anti-Inflammatory and Pro-Inflammatory Gut Microbiota That Determine Graft Survival
Introduction: The gut microbiota induce and train the host immune system. Whether microbiota from contrasting environments of colitic or pregnant mice are pro- or anti-inflammatory…2018 American Transplant Congress
The Impact of Aorto-Iliac Calcifications on Patient and Graft Survival in Renal Transplant Recipients Using the TASC II Classification
Introduction: Kidney transplantation (KTx) is the therapy of choice in patients with end-stage renal disease. Aorto-iliac calcifications (AIC) are a relative contra-indication for KTx, even…2018 American Transplant Congress
Kidney Transplantation in ESKD Patients with a History of Sickle Cell Disease/Trait
Introduction:Kidney transplantation in Sickle Cell Disease patients is fraught with complications, including increased risk of infection and thrombosis. We present long term outcomes of patients…2018 American Transplant Congress
The Regulatory Role of Plasma Cells (as Bregs) is Counterbalanced by a NOVEL Inflammatory Role in Murine Transplant and Autoimmune Models
Plasma Cells (PCs; B220lowCD138hiBlimp1+Ig+) in LN and spleen were shown to be the major source of B cell lineage IL-10, and absence of PCs worsens…2018 American Transplant Congress
Outcomes from 194 Consecutive Split Left Liver Transplants: Comparison of Living versus Deceased Donors
Recanati/Miller Transplant Institute, Mount Sinai Hospital, New York.
Methods:Analysis of long term outcomes of 194 consecutive left lateral segment grafts (LLS) including 94 living (LD) and 99 deceased (DD) donor grafts (1992 -…2018 American Transplant Congress
Outcomes after Kidney Transplantation in Patients with AL Amyloid Following Autologous Stem Cell Transplantation
BackgroundAL amyloidosis results in kidney failure in about 15-30% of patients and is considered a relative contraindication for kidney transplantation. There is limited data on…2018 American Transplant Congress
Shikonin Inhibits Th17 Development through Repressing STAT3 Activation
Background: Th17-mediated inflammatory responses are detrimental for allograft acceptance and long-term survival after transplantation. Shikonin is a naphthoquinone pigment isolated from a traditional medicinal herb…
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