2019 American Transplant Congress
Supercooling Preservation Prolonged Mouse Cardiac Graft Cold Ischemia Time
*Purpose: Supercooling preservation techniques store a donor organ below 0°C without freezing. This has great advantages in inhibiting metabolism and preserving the organ in comparison…2018 American Transplant Congress
VLA-4 Blockade Inhibits Early Endogenous Memory CD8 T Cell Infiltration into Higher Risk Cardiac Allografts and Donor-Reactive T Cell Priming
Endogenous memory CD8 T cells infiltrate MHC-mismatched cardiac allografts within 24 hrs after graft reperfusion in mice. Our recent studies indicate that prolonged cold ischemic…2018 American Transplant Congress
Antibody-Verified Eplet Mismatches as Determinants of Premature Kidney Transplant Loss
Introduction: HLA matching at the epitope level offers new opportunities to identify compatible donors for transplant candidates. HLAMatchmaker deduces B-cell epitope ('eplets' in HLAMatchmaker) mismatches…2018 American Transplant Congress
Validation of an Integrative and Dynamic Prognostic Score for Response to Therapy in Solid Organ Transplants
Paris Translational Center for Organ Transplantation, Paris, France.
Drug development in transplantation has diminished due to the lack of suitable endpoints for predicting graft failure. We sought to validate the performance of an…2018 American Transplant Congress
Variation in Cost of Death and Graft Failure across All Solid Organs
1St. Louis Univ, St. Louis, MO; 2SRTR, Minneapolis, MN; 3Lahey Hosp & Med Ctr, Burlington, VT.
Medicare costs for transplant vary considerably by organ, and costs in the second posttransplant year (Y2) are lower than in the first (Y1). Variability in…2018 American Transplant Congress
Identification of Macrophage Innate Receptors in Recognition and Rejection of Allogeneic Non-Self in Transplantation
Recent studies in several labs provide compelling evidence that the innate immune cells can recognize and reject allogeneic non-self in an antigen-specific manner, but the…2018 American Transplant Congress
No Correlation between US News "Best Hospitals" Rank and Outcome of Liver or Kidney Transplantation
Introduction:Increased need for quality and cost effective healthcare has led to lay-press rankings such as U.S. News and World Report (USN). USN's “Best Hospitals” publication…2018 American Transplant Congress
Should Kidneys from Donation after Cardiac Death Expanded Criteria Donors Be Transplanted?
Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Introduction: Expanded criteria donor (ECD) kidneys increase the organ pool but their discard rate remains high, especially in the setting of donation after cardiac death…2018 American Transplant Congress
Failure to Remove De Novo Donor-Specific HLA Antibodies is Influenced by Antibody Properties and Identifies Kidney Recipients with Late Antibody-Mediated Rejection Destined to Graft Loss
Late antibody-mediated rejection (AMR) is the major cause of renal allograft loss. Current research is focusing on identifying a performant risk stratification in order to…2018 American Transplant Congress
Successful Management of Simultaneous Liver-Kidney Transplant Recipient with Primary Hyperoxaluria Using Intensive Continuous Dialysis
The rate of oxalate production in patients with Primary Hyperoxaluria type 1 (PH-1) exceeds the rate of removal, leading to progressive worsening of kidney function.…
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