Articles tagged "Graft survival"

2019 American Transplant Congress
Have Graft Outcomes Improved for Pediatric Transplant Recipients Since the Implementation the Kidney Allocation System
C. S. Bell¹, S. Hebert², A. De Golovine³, R. Swinford¹
¹Division of Pediatric Nephrology & Hypertension, McGovern Medical School at UTHealth - Houston, Houston, TX, ²Division of Nephrology, Department of Internal Medicine, Houston Methodist Hospital, Houston, TX, ³Renal Diseases &Hypertension, McGovern Medical School at UTHealth - Houston, Houston, TX
*Purpose: The new kidney allocation system (KAS) that utilizes a Kidney Donor Profile Index (KDPI) in matching transplant recipients to donors was implemented in December…
2019 American Transplant Congress
The Protective Effects of siRNA Conjugated Nanoparticles in Pancreatic Islet Cells after Transplant
T. Pomposelli, P. Wang, Y. Ariyoshi, K. Takeuchi, C. Schuetz, A. Moore, K. Yamada
Columbia Center for Translational Immunology, Columbia University, New York, NY
*Purpose: To utilize a novel technology involving siRNA conjugated iron oxide nanoparticles to protect against ischemic damage to islet cells before transplant, therefore minimizing the…
2019 American Transplant Congress
Transplant Nephrologist
K. A. AlMeshari¹, D. Broering², I. Alahmadi³, S. Raza³, T. Ali³, F. Alzayer⁴, A. Algharabli⁴
¹King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ²Organ Transplant Center, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ³Kidney & Pancreas Transplantation Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, ⁴Department of Pathology & Laboratory Medicine, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
*Purpose: Matching rates of very highly sensitized patients with cPRA of 91 - 100% (VHSP) and blood type O recipients of ABO incompatible donors (ABO…
2019 American Transplant Congress
Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 10 Years Follow-Up
Y. Watarai¹, S. Narumi¹, T. Tomosugi¹, K. Futamura², M. Okada¹, M. Tsujita², T. Hiramitsu¹, T. Kobayashi³, N. Goto²
¹Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan, ²Transplant Nephrology, Nagoya Daini Red Cross Hospital, Nagoya, Japan, ³Kidney Transplantation, Aichi Medical University, Nagoya, Japan
*Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study from our institute…
2019 American Transplant Congress
Urinary Extracellular Vesicles-Related Protein Biomarkers for the Non-Invasive Monitoring of Rejection in Kidney Transplanted Patients
L. Carreras-Planella¹, I. Bancu², D. Cucchiari³, L. Cañas², J. Juega², M. Franquesa¹, M. Perez-Mir², I. Revuelta³, F. Diekman⁴, R. Lauzurica², F. Borràs¹
¹REMAR-IVECAT Group, Institut Germans Trias i Pujol, Badalona, Spain, ²Nephrology- Renal Transplant Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ³Dept. Nefrologia i Trasplantament Renal, Institut Clínicde Nefrologia i Urologia (ICNU), Hospital Clinic, Barcelona, Spain, ⁴Dept. Nefrologia i Trasplantament Renal, Institut Clínicde Nefrologia i Urologia (ICNU), Hospital Clinic, Badalona, Spain
*Purpose: Chronic kidney rejection is currently the main cause of graft losses. Blood and urine analyses to monitor kidney transplanted patients are not specific, and…
2019 American Transplant Congress
Induction Therapy in Elderly Kidney Transplant Recipients with Low Immunological Risk
C. Masset¹, J. Boucquemont², V. Garrigue³, M. Ladrière⁴, F. Buron⁵, E. Cassuto⁶, Y. Foucher², J. Dantal¹
¹University Hospital of Nantes, Nantes, France, ²University of Nantes, Nantes, France, ³University Hospital of Montpellier, Montpellier, France, ⁴University Hospital of Nancy, Nancy, France, ⁵University Hospital of Lyon, Lyon, France, ⁶University Hospital of Nice, Nice, France
*Purpose: Thymoglobulin (ATG) and Basiliximab (BSX) lead to similar rejection rates in low immunological risk patients. ATG seems to be associated with infectious and malignancy…
2019 American Transplant Congress
Leukopenia in Older Kidney Transplant Recipients is Associated with Decreased Allograft Survival and Increased Patient Survival
R. Rodriguez, A. Price, K. Soliman, R. Vinaya, D. Lazarus, M. Casey, M. Labonte, L. Erbe, M. Shearer, D. Taber, M. Posadas Salas
Transplant Nephrology, Medical University of South Carolina, Charleston, SC
*Purpose: Older kidney transplant recipients are vulnerable to side effects of immunosuppression (IS) including leukopenia. Providers often reduce MMF dose in response to leukopenia. This…
2019 American Transplant Congress
Cidofovir for BK Nephropathy Rescue Treatment: A Single Center Experience
J. Slatinska¹, E. Honsova², T. Rohal¹, A. Slavcev³, P. Hruba⁴, O. Viklicky¹
¹Nephrology, IKEM, Prague, Czech Republic, ²Pathology, IKEM, Prague, Czech Republic, ³Immunology, IKEM, Prague, Czech Republic, ⁴Transplant Laboratory, IKEM, Prague, Czech Republic
*Purpose: Cidofovir is a potentially nephrotoxic antiviral drug used primarily as a treatment for CMV retinitis however due to its potent antiviral effects has been…
2019 American Transplant Congress
Treg Lymphotoxin and Lymphatic Endothelial Cell Lymphotoxin Receptor Interactions Are Required for Treg Stability and Allograft Protection
V. Saxena, W. Piao, L. Li, C. M. Palusckievicz, Y. Xiong, T. Simon, J. S. Bromberg
U Maryland, Baltimore, MD
*Purpose: Regulatory T cells (Treg) restrain allograft rejection through suppressor functions that are dependent upon expression of the transcription factor Foxp3, their proper migration, and…
2019 American Transplant Congress
Increased Frequency of Myeloid-Derived Suppressor Cells Contributing to Prolong Skin Allograft Survival in Aged Mice
W. Lee, Y. Wang, T. Wu, C. Cheng, C. Lee, T. Wu, H. Chou, K. Chan
General Surgery, Chang-gung Hospital, Taoyuan, Taiwan
*Purpose: Currently, aged people are increasing and more and more aged people have organ transplantation. The immunity in aged people is weaker than young people.…