Articles tagged "Graft survival"

2019 American Transplant Congress
Specific Donor/Recipient HLA Disparities are Associated with Better Long-Term Kidney Allograft Survival among 4-, 5-, and 6-HLA (A/B/DR)-Mismatched Pairs
D. Bekbolsynov, H. Zhang, B. Mierzejewska, M. Rees, K. Xu, S. Stepkowski
University of Toledo, Toledo, OH
*Purpose: The vast majority of deceased donor kidneys are allocated without any consideration for the HLA disparities, which may improve or worsen the survival the…
2019 American Transplant Congress
Senescent Cell Clearance with Senolytic Drugs Improves Cardiac Allograft Survival by Targeting mt-DNA Mediated Immune Responses
J. Iske¹, M. Koichiro¹, M. Seyda¹, T. Heinbokel¹, Y. Nian¹, R. Maenosono¹, H. Azuma¹, C. Falk², T. Tchokonia³, J. Kirkland³, A. Elkhal¹, S. Tullius¹
¹Transplant Surgery, Brigham and Women's Hospital, Boston, MA, ²Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany, ³Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN
*Purpose: Older organs represent an underutilized potential. We dissected alloimmune responses when transplanting older organs and tested if the depletion of senescent cells in older…
2019 American Transplant Congress
Non-adherence With Diet And Dialysis Prescription: Predictors Of Non-adherence Post-transplant?
A. Padiyar¹, A. Agrawal¹, D. Hricik¹, P. Bate², J. Rockwell², A. Eliason², N. Sarabu¹, A. Jittirat¹, K. Yadav², E. Sanchez², M. Debroy², V. Humphreville², J. Rabets², A. Palanisamy², K. Chavin²
¹Medicine, Nephrology, University Hospitals Cleveland Medical Center, Cleveland, OH, ²Transplant Surgery, University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Perceived non-adherence with diet and dialysis prescription prior to transplant may be seen as a risk for non-adherence with immunosuppression post-transplant. The importance of…
2019 American Transplant Congress
Outcomes Of Single And En-bloc Pediatric Kidneys According To Kdpi
M. Sampaio, E. Lum, A. Gritsch, S. Bunnapradist
David Geffen Sch of Med at UCLA, Los Angeles, CA
*Purpose: There is no consensus on whether a very young kidney should be used as en-bloc or single. We studied the association of KDPI in…
2019 American Transplant Congress
Endothelial Cell Cytoskeleton Rearrangement (ECCSKR) and Endothelial to Mesenchymal Transition (EndoMT) in Liver Allografts Following Acute Rejection (AR): Its Significance on the Development of Liver Fibrosis (LF) and Graft Survival
B. H. Ozdemir¹, G. Ozgun¹, E. H. Ayvazoglu Soy², N. Haberal¹, G. Moray², M. Haberal²
¹Pathology, Baskent University, Ankara, Turkey, ²Transplantation, Baskent University, Ankara, Turkey
*Purpose: Endothelial cell (EC) cytoskeleton is critical for EC adhesion and permeability. CSKR initiates permeability and influx of leukocytes which in turn leads to increased…
2019 American Transplant Congress
Comparable Outcomes of Deceased Donor Liver Transplant Outcomes in Recipients with Previous Abdominal Surgery (PAS) after Pre Listing Surgical Categorization. A Propensity-Score Matched Pair Analysis
H. Sharma, H. Bohorquez, D. Oganesyan, D. Bruce, E. Bugeaud, I. Carmody, A. Cohen, J. Seal, D. Sonnier, G. Loss
Department of Transplant Surgery, Ochsner Medical Center, New Orleans, LA
*Purpose: Few studies have evaluated the impact of previous abdominal surgery (PAS) on deceased donor liver transplantation-(DDLT). Furthermore, there is no evidence of impact of…
2019 American Transplant Congress
Outcomes From Very Old Deceased Kidney Donors For Transplantation
E. Guillen¹, P. Ventura-Aguiar¹, A. Ruiz², G. Piñeiro¹, D. Cucchiari¹, I. Revuelta¹, V. Torregrosa¹, F. Cofan¹, E. De Sousa¹, N. Esforzado¹, M. Musquera³, L. Peri³, F. Oppenheimer¹, F. Diekmann¹
¹Renal Transplant Unit, Nephrology and Kidney Transplantation Department, Hospital Clinic, Barcelona, Spain, ²Organ Transplantation Coordination Department, Hospital Clinic, Barcelona, Spain, ³Renal Transplant Unit, Urology Department, Hospital Clinic, Barcelona, Spain
*Purpose: Age of deceased donors is increasing, so ensuring the viability of these organs is essential for renal transplantation to continue being the best option…
2019 American Transplant Congress
Perioperative Lactate Levels Are Sensitive Marker to Predict Early Allograft Dysfunction and Short-Term Graft Failure after Liver Transplant
K. Takahashi¹, S. Nagai², K. Collins², M. Rizzari², M. Safwan², S. Jafri³, T. Oda¹, A. Yoshida², M. Abouljoud²
¹Surgery, University of Tsukuba, Tsukuba, Japan, ²Surgery, Henry Ford Hospital, Detroit, MI, ³Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: Lactate is one of the most frequently used makers to understand real-time graft function after liver transplant (LT). This study aimed to investigate risk…
2019 American Transplant Congress
Kidney Transplant Outcomes among Patients with Obstructive Sleep Apnea
R. Tiwari, B. Lyu, S. Alagusundaramoorthy, B. C. Astor, D. Mandelbrot, S. Parajuli
University of Wisconsin, Madison, WI
*Purpose: Obstructive sleep apnea (OSA) is known to have deleterious effects on health and survival among the general population and patients with chronic kidney disease.…
2019 American Transplant Congress
Page Kidney Phenomenon in a Trauma Patient: A Case Report and Recommendations for Management
M. M. Estrada, D. R. Hall, W. Dar, J. S. Bynon
University of Texas Health Science Center at Houston, Houston, TX
*Purpose: Unintentional injuries result in over 30 million emergency room visits annually in the United States. With almost 20 thousand renal transplants performed in 2017,…