Articles tagged "Graft survival"

2020 American Transplant Congress
Outcomes of Simultaneous Pancreas and Kidney Transplantation Based on Donor Resuscitation
F. Messner¹, J. W. Etra², Y. Yu³, K. Jackson², A. B. Massie², G. Brandacher², S. Schneeberger⁴, C. Margreiter⁴, D. L. Segev²
¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, ³Department of Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD, ⁴Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria
*Purpose: It has been hypothesized that transplanting simultaneous pancreas kidney (SPK) grafts from donors with a history of cardiac arrest and cardiopulmonary resuscitation (CACPR) leads…
2020 American Transplant Congress
Comparison of 4 vs 14 Days Early Steroid Withdrawal in Kidney Transplant Recipients
O. Adebiyi, J. Chen, B. Brady, S. Mietz, T. Taber, D. Mishler, M. Yaqub, W. Goggins, A. Sharfuddin
Indiana University, Indianapolis, IN
*Purpose: The optimal duration, as well as the dose of the initial steroid use, is not known as it varies widely among institutions that have…
2020 American Transplant Congress
HLA-DQ Plays an Important Role in Graft Survival in African American Transplant Recipients
L. M. Rebellato¹, W. Irish², D. Leeser², J. Tuttle², C. E. Haisch²
¹Pathology, The Brody School of Medicine at ECU, Greenville, NC, ²Surgery, The Brody School of Medicine at ECU, Greenville, NC
*Purpose: Our kidney transplant (KTx) program serves a medically underserved and racially diverse area of a southern state. The purpose of this study was to…
2020 American Transplant Congress
Under-Diagnosed Hyperoxalosis in Transplant-Listed Patients
A. Tariq, L. Lakhani, W. Greenspan, S. Alasfar, F. Naqvi, D. Brennan
Nephrology, Johns Hopkins University, Baltimore, MD
*Purpose: In an era of increasing kidney transplantation (KTx), hyperoxalosis remains an under-recognized cause for allograft failure. Bariatric interventions are significant risk factors for oxalosis,…
2020 American Transplant Congress
Lacripep^TM and its Analogs Act as Novel Interventional Agents to Promote Long-Term Islet Transplantation Outcomes
M. Ma¹, K. Teixeira², G. Laurie², K. Brayman¹, P. Chhabra¹
¹Department of Surgery, University of Virginia Health System, Charlottesville, VA, ²Department of Cell Biology, University of Virginia Health System, Charlottesville, VA
*Purpose: To study the prosecretory, prosurvival, and mitogenic effect of Lacripep™ and its analogs in enhancing islet viability, increasing insulin secretion and promoting long-term islet…
2020 American Transplant Congress
Need for Pre-Transplant Midodrine Does Not Negatively Impact Outcomes after Simultaneous Liver-Kidney Transplant
P. Barman¹, L. King², C. Berg², A. Barbas², L. McElroy², A. Parish², D. Niedzwiecki², Y. Patel²
¹University of California, San Diego, San Diego, CA, ²Duke University, Durham, NC
*Purpose: Patients with cirrhosis often develop chronic hypotension, which contributes to kidney dysfunction. Midodrine can improve hemodynamics and renal perfusion in these hypotensive patients. There…
2020 American Transplant Congress
The Effect of Desensitization Therapy on Sex Disparity in Living Kidney Transplantation
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Sex- and gender-based disparities which have shown women to have lower access to kidney transplantation have been reported. In living kidney transplantation (LKT), pregnancy-related…
2020 American Transplant Congress
TRANSFORM Study (NCT01950819): Application of the Ibox Clinical Trial Simulation Tool to Project Long-Term Kidney Allograft Outcome
G. Divard¹, O. Aubert¹, M. Raynaud¹, J. Pascual², F. Vincenti³, P. Bernhardt⁴, C. Legendre¹, A. Loupy¹, .. on behalf of TRANSFORM Investigators⁵
¹INSERM U970, Paris Transplant Group, Paris, France, ²Department of Nephrology, Hospital del Mar/Universitat Autònoma de Barcelona, Barcelona, Spain, ³Department of Surgery/Kidney Transplant Service, University of California, San Francisco, CA, ⁴Research and Development, Novartis Pharma AG, Basel, Switzerland, ⁵TRANSFORM Investigators, Basel, Switzerland
*Purpose: The development of pharmaceutical agents in transplantation is currently limited by long waits for hard endpoints. We sought to use a risk stratification system…
2020 American Transplant Congress
Post-Transplant Hepatic CHOP Expression Dictates Clinical Outcomes in Liver Transplantation
H. Hirao¹, T. Ito¹, K. Nakamura², S. Kageyama¹, K. Kadono¹, H. Kojima¹, K. J. Dery¹, S. Younan¹, R. W. Busuttil¹, F. M. Kaldas¹, J. W. Kupiec‐Weglinski¹
¹UCLA, Los Angeles, CA, ²Kyoto University, Kyoto, Japan
*Purpose: Endoplasmic reticulum (ER) stress plays a pivotal role in the mechanism of liver ischemia reperfusion injury (IRI). Although we and others have demonstrated the…
2020 American Transplant Congress
Early Calculation of the Tacrolimus Concentration-to-Dose Ratio Does Not Predict Outcomes after Renal Transplantation
K. Schütte-Nütgen, I. Bartmann, B. Suwelack, S. Reuter
Department of Internal Medicine D, University Hospital Münster, Münster, Germany
*Purpose: There is emerging interest in the concentration-to-dose (C/D) ratio of tacrolimus (Tac) as it is linked to outcomes after renal transplantation (RTx). Recently, we…