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American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2020 American Transplant Congress

    The Significance of Donor Gender on Graft Survival and Histological Ischemia Reperfusion Injury in Liver Transplant Patients

    T. Ito, S. Kageyama, K. J. Dery, K. Nakamura, S. M. Younan, M. M. Lu, J. DiNorcia III, V. G. Agoian, H. Yersis, D. G. Farmer, R. W. Busuttil, F. M. Kaldas

    Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA

    *Purpose: Experimental animal models have demonstrated improved ability of females (F) to recover from ischemia-reperfusion injury (IRI) compared with males (M). Recent work combining human…
  • 2020 American Transplant Congress

    NASH is the Leading Indication for Liver Transplantation in Elderly Patients

    J. A. Steggerda1, J. Yang2, V. Sundaaram2, N. Alkouri3, W. Ayoub2, I. K. Kim1, M. Noureddin2

    1Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, 2Hepatology, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, 3Gastroenterology, University of Texas Health- San Antonio, San Antonio, TX

    *Purpose: Non-alcoholic steatohepatitis (NASH) is an increasingly prevalent cause of end-stage liver disease (ESLD) and indication for liver transplantation (LT) in the United States and…
  • 2020 American Transplant Congress

    Impact of Severity of Glomerulosclerosis on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury

    A. Brar1, A. Gruessner2, D. Adey1, M. Salifu2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: With long waitlist times for renal transplantation,there is a need to reduce discard rates of donor kidneys.The purpose of this study is to assess…
  • 2020 American Transplant Congress

    Comparative Analysis of Risk Factors and Outcomes in Kidney Transplant Recipients with Lung Cancer and Those with No Malignancy: UNOS Data Set

    H. Patel1, V. Nissaisorakarn2, E. Sula Karrecci1, N. Agrawal1, F. Cardarelli1

    1Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 2Department of Internal Medicine, Metrowest Medical Center, Boston, MA

    *Purpose: Transplant recipients are at increased risk for malignancy. Patients who develop cancer after transplant have worse outcomes, especially those with lung cancer. Transplant-related risk…
  • 2020 American Transplant Congress

    Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients

    A. Brar1, A. Gruessner2, D. Adey1, M. Salifu2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…
  • 2020 American Transplant Congress

    Graft Perfusion with an Hsp90 Inhibitor Prolongs Graft Survival in Murine Heart Transplantation by Modulating Expression of Cyclin-Dependent Kinases and the Senolytic Effect

    T. Tanaka, T. Maehana, N. Masumori

    Department of Urology, Sapporo Medical University, Sapporo, Japan

    *Purpose: We have previously demonstrated that administration of alvespimycin, a heat shock protein 90 (HSP90) inhibitor, prolongs the allograft survival in murine skin and heart…
  • 2020 American Transplant Congress

    Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression

    I. Booth1, J. Casale1, S. Freedman1, B. Ravichandran1, J. Scalea2, A. Haririan2, B. Masters1

    1Pharmacy, University of Maryland Medical Center, Baltimore, MD, 2Medicine, University of Maryland Medical Center, Baltimore, MD

    *Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…
  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
  • 2020 American Transplant Congress

    Feasibility and Long Term Safety of T Regulatory Cell Therapy in Kidney Transplantation

    P. N. Harden1, D. Game2, J. Van der Net1, F. Issa3, W. Petchey1, M. Brook1, P. Friend1, R. Hilton4, G. Lombardi5, K. Wood3

    1Kidney Transplantation, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, 2Kidney Transplantation, Guys and St Thomas's Hospital, London, United Kingdom, 3Transplant Immunology Research Group, Oxford University, Oxford, United Kingdom, 4Kidney Transplantation, Guys and St Thomas's Hospital, Oxford, United Kingdom, 5Transplant Immunology Group, Kings Healthcare Partners, London, United Kingdom

    *Purpose: A sequential clinical trial of autologous polyclonal T regulatory cellular therapy compared with a standardised reference cohort of live donor kidney transplant recipients. The…
  • 2020 American Transplant Congress

    Post- Transplant Recurrence of IgA Nephropathy: HLA as a Predictive Factor

    C. R. Kavanagh1, N. G. Jain1, R. Vasilescu2, J. Kamal3, I. Batal2

    1Pediatric Nephrology, Columbia University Medical Center, New York, NY, 2Pathology, Columbia University Medical Center, New York, NY, 3Surgery, Columbia University Medical Center, New York, NY

    *Purpose: Genomic studies have identified several HLA antigens to be associated with IgA Nephropathy in the native kidney. In contrast to the native kidney, there…
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