Articles tagged "Graft survival"

2020 American Transplant Congress
Cardiovascular Improvement after Pancreatic Transplantation
S. Y. Suen¹, T. Sparkes¹, R. Kalil², B. Ravichandran¹
¹Pharmacy, University of Maryland Medical Center, Baltimore, MD, ²Nephrology, University of Maryland Medical Center, Baltimore, MD
*Purpose: Cardiovascular disease is a common cause of mortality in patients with uncontrolled diabetes. The purpose of this study is to assess whether patients receiving…
2020 American Transplant Congress
Renal Transplantation in Jehovah’s Witnesses: A Single-Center Experience
J. Rao, A. Matas, S. Jackson, V. Humphreville
Transplant Surgery, University of Minnesota, Minneapolis, MN
*Purpose: Transplant in Jehovah's Witnesses (JW) has been controversial due to their religious beliefs resulting in frequent refusal to accept a wide range of blood…
2020 American Transplant Congress
Simultaneous Pancreas-Kidney Transplant: – The Effects of Early Steroid Withdrawal, Donor and Recipient Variables on Patient Survival
D. Kloda¹, M. McLeod², M. Romine¹, J. Ladowski², J. Locke¹, C. Young¹
¹Department of Surgery - Division of Transplantation, University of Alabama, Birmingham, AL, ²Department of Surgery, University of Alabama, Birmingham, AL
*Purpose: Simultaneous pancreas-kidney transplantation (SPK) improves survival in type I diabetic patients with end stage renal disease (ESRD). Corticosteroids have traditionally been an integral component…
2020 American Transplant Congress
Tumor of Transplanted Kidney: Graft Resection Preserves Renal Function with Good Long-Term Oncologic Outcome
J. Chlupac, T. Marada, M. Kudla, L. Janousek, J. Fronek
Transplantation Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Incidence of urologic tumors is increased in renal transplant recipients. In case of a kidney transplant neoplasm, the graft-nephrectomy and hemodialysis reduce the quality…
2020 American Transplant Congress
The Influence of Donor Kidney to Recipient Body Weight Ratio on Long-Term Outcomes of Living-Donor Kidney Transplantation
N. Sato, Y. Kakuta, T. Kanzawa, K. Unagami, M. Okumi, H. Ishida, K. Tanabe
Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
*Purpose: We often experience the incompatibility in size between the kidney graft and recipient in living-donor kidney transplantation. This study evaluated the effect of the…
2020 American Transplant Congress
Lymphotoxin Beta Receptor Regulates Draining Lymph Node Structure and Treg Migration
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, C. C. Palusckievicz¹, T. Simon¹, M. W. Shirkey¹, R. Abdi², J. S. Bromberg¹
¹University of Maryland, Baltimore, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: To induce tolerance, regulatory T cells (Treg) are required to migrate from tissues via afferent lymphatic vessels (LV) to the draining lymph node (dLN).…
2020 American Transplant Congress
Prospective, Randomized Study of Conversion from Calcineurin Inhibitor (CNI)- to Belatacept (BELA)-Based Maintenance Immunosuppression in Renal Transplant Recipients
K. Budde¹, R. Prashar², H. Haller³, M. Rial⁴, N. Kamar⁵, A. Agarwal⁶, J. de Fijter⁷, L. Rostaing⁸, S. Berger⁹, A. Djamali¹⁰, N. Leca¹¹, L. Allamassey¹², S. Gao¹², M. Polinsky¹², F. Vincenti¹³
¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Henry Ford Hospital, Detroit, MI, ³The Hannover Medical School, Hannover, Germany, ⁴Instituto de Nefrologia, Nephrology SA, Buenos Aires, Argentina, ⁵University of Toulouse, Toulouse, France, ⁶UVA Health, Charlottesville, VA, ⁷Leiden University Medical Center, Leiden, Netherlands, ⁸Université Grenoble Alpes, Saint-Martin-d'Hères, France, ⁹University Medical Centre Groningen, Groningen, Netherlands, ¹⁰University of Wisconsin, Madison, WI, ¹¹UW Medical Center, Seattle, WA, ¹²Bristol-Myers Squibb, Princeton, NJ, ¹³University of California, San Francisco, San Francisco, CA
*Purpose: CNIs are associated with adverse systemic and nephrotoxic effects that negatively impact long-term patient and graft survival. In a phase 2 study, switching renal…
2020 American Transplant Congress
The Effects of DGF after Deceased Donor Renal Transplantation Differ by KDPI
M. Molinari¹, W. Chang¹, D. Jorgensen², C. Wu³, S. Hariharan³
¹Surgery, University of Pittsburgh Medical Centre, Pittsburgh, PA, ²Biostatistics, University of Pittsburgh Medical Centre, Pittsburgh, PA, ³Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA
*Purpose: We analyzed the effects of DGF on: (1) graft survival, (2) patient survival and (3) eGFR of adult recipients of deceased donor kidney transplants…
2020 American Transplant Congress
Single Dose Rituximab and Anti-Thymocyte Globulin (ATG) Induction in Hypersensitized Kidney Transplant Recipients
A. X. Wang, U. Wang, S. Busque, C. R. Lenihan
Stanford University School of Medicine, Stanford, CA
*Purpose: Hypersensitized kidney transplant recipients (calculated panel reactive antibody (cPRA) ≥98%) may represent a population at high risk of posttransplant immunologic events. While access to…
2020 American Transplant Congress
Life Supporting Orthotopic Cardiac Xenotransplantation from Genetically Engineered Donor Pigs
A. K. Singh¹, C. E. Goerlich¹, T. Zhang¹, I. Tatarov¹, P. Odonkor¹, E. Strauss¹, B. Williams¹, B. Lewis¹, A. Hershfeld¹, F. Sentz¹, D. Ayares², D. Kaczorowski¹, B. Griffith¹, M. M. Mohiuddin¹
¹Department of Surgery, University of Maryland Baltimore, Baltimore, MD, ²Revivicor Inc, Blacksburg, VA
*Purpose: Cardiac xenotransplantation (CXTx) might be an alternative treatment for end-stage cardiac failure patients. The prolonged survival of a heterotopic genetically-engineered (GE) pig heart is…