ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2020 American Transplant Congress

    Short Recipient Warm Ischemia Time Improves Graft Survival in Liver Transplantation from Donation after Brain Death: 20-Year Experience of Liver Transplantation

    A. Al-Kurd, T. Kitajima, K. Delvecchio, A. M. Elsabbagh, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, S. Nagai

    Transplant Institute, Henry Ford Hospital, Detroit, MI

    *Purpose: Although the correlation between warm ischemia time (WIT) and the outcomes of liver transplantation has been extensively studied, few investigations have focused on the…
  • 2020 American Transplant Congress

    End-Hypothermic Oxygenated Machine Perfusion after Static Cold Storage versus Static Cold Storage Alone in Kidneys from Extended Criteria Brain-Dead Donors: An International Randomized Controlled Trial

    P. Husen1, C. Boffa2, I. Jochmans3, C. Krikke4, L. Davies2, H. Hofker4, J. Pirenne3, R. Ploeg2, A. Paul1

    1General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany, 2Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 3University Hospitals Leuven, Leuven, Belgium, 4University Medical Center Groningen, Groningen, Netherlands

    *Purpose: A prospective, randomized, single-blinded, multicenter trial comparing the effect of short-term 'in house' oxygenated hypothermic machine preservation (End-HMPO2) following static cold storage (SCS) versus…
  • 2020 American Transplant Congress

    The Significance of Donor Gender on Graft Survival and Histological Ischemia Reperfusion Injury in Liver Transplant Patients

    T. Ito, S. Kageyama, K. J. Dery, K. Nakamura, S. M. Younan, M. M. Lu, J. DiNorcia III, V. G. Agoian, H. Yersis, D. G. Farmer, R. W. Busuttil, F. M. Kaldas

    Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA

    *Purpose: Experimental animal models have demonstrated improved ability of females (F) to recover from ischemia-reperfusion injury (IRI) compared with males (M). Recent work combining human…
  • 2020 American Transplant Congress

    NASH is the Leading Indication for Liver Transplantation in Elderly Patients

    J. A. Steggerda1, J. Yang2, V. Sundaaram2, N. Alkouri3, W. Ayoub2, I. K. Kim1, M. Noureddin2

    1Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, 2Hepatology, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, 3Gastroenterology, University of Texas Health- San Antonio, San Antonio, TX

    *Purpose: Non-alcoholic steatohepatitis (NASH) is an increasingly prevalent cause of end-stage liver disease (ESLD) and indication for liver transplantation (LT) in the United States and…
  • 2020 American Transplant Congress

    Impact of Severity of Glomerulosclerosis on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury

    A. Brar1, A. Gruessner2, D. Adey1, M. Salifu2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: With long waitlist times for renal transplantation,there is a need to reduce discard rates of donor kidneys.The purpose of this study is to assess…
  • 2020 American Transplant Congress

    A Data-Driven Approach to Defining the Volume-Outcome Relationship in Renal Transplantation

    E. L. Godfrey1, M. D. Bailey1, W. C. Frankel1, A. Rana2

    1Baylor College of Medicine, Houston, TX, 2Division of Abdominal Transplantation, Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: Advances in immunosuppression and management continually improve short- and long-term outcomes of renal transplantation. However, center volume and expertise, while commonly believed to affect…
  • 2020 American Transplant Congress

    Impact of Kidney Donor Profile Index (KDPI) on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury

    A. Brar1, M. Salifu2, D. Adey1, A. Gruessner2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with donor acute kidney injury (AKI) are discarded at a higher rate. The purpose of the study is to assess long term renal…
  • 2020 American Transplant Congress

    Long-Term Islet Allo- and Xenograft Survival is Promoted by Immunoglobulin M Immunotherapy

    M. Ma, K. Brayman, P. Chhabra

    Department of Surgery, University of Virginia Health System, Charlottesville, VA

    *Purpose: To investigate if islet allo- and xenotransplant rejection is mitigated by IgM immunotherapy.*Methods: a) New onset diabetic NOD mice (n=14) were treated with IgM…
  • 2020 American Transplant Congress

    Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model

    S. Jain1, R. Plenter2, T. Nydam2, A. Jani1

    1Renal, University of Colorado, Aurora, CO, 2Transplant Microsurgery Program, University of Colorado, Aurora, CO

    *Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…
  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
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