ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2020 American Transplant Congress

    A Data-Driven Approach to Defining the Volume-Outcome Relationship in Renal Transplantation

    E. L. Godfrey1, M. D. Bailey1, W. C. Frankel1, A. Rana2

    1Baylor College of Medicine, Houston, TX, 2Division of Abdominal Transplantation, Department of Surgery, Baylor College of Medicine, Houston, TX

    *Purpose: Advances in immunosuppression and management continually improve short- and long-term outcomes of renal transplantation. However, center volume and expertise, while commonly believed to affect…
  • 2020 American Transplant Congress

    Impact of Kidney Donor Profile Index (KDPI) on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury

    A. Brar1, M. Salifu2, D. Adey1, A. Gruessner2

    1University of California, San Francisco, San Francisco, CA, 2SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Kidneys with donor acute kidney injury (AKI) are discarded at a higher rate. The purpose of the study is to assess long term renal…
  • 2020 American Transplant Congress

    Long-Term Islet Allo- and Xenograft Survival is Promoted by Immunoglobulin M Immunotherapy

    M. Ma, K. Brayman, P. Chhabra

    Department of Surgery, University of Virginia Health System, Charlottesville, VA

    *Purpose: To investigate if islet allo- and xenotransplant rejection is mitigated by IgM immunotherapy.*Methods: a) New onset diabetic NOD mice (n=14) were treated with IgM…
  • 2020 American Transplant Congress

    Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model

    S. Jain1, R. Plenter2, T. Nydam2, A. Jani1

    1Renal, University of Colorado, Aurora, CO, 2Transplant Microsurgery Program, University of Colorado, Aurora, CO

    *Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…
  • 2020 American Transplant Congress

    The Impact of Occult Graft Fibrosis on Clinical Outcomes in Human Liver Transplant Recipients

    H. Hirao1, T. Ito1, B. V. Naini1, K. Nakamura2, S. Kageyama1, K. Kadono1, H. Kojima1, K. J. Dery1, S. Younan1, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1UCLA, Los Angeles, CA, 2Kyoto University, Kyoto, Japan

    *Purpose: Although liver transplantation (LT) has become a standard therapy for end-stage liver disease, early allograft dysfunction (EAD) and graft rejection remain serious unsolved problems.…
  • 2020 American Transplant Congress

    Feasibility and Long Term Safety of T Regulatory Cell Therapy in Kidney Transplantation

    P. N. Harden1, D. Game2, J. Van der Net1, F. Issa3, W. Petchey1, M. Brook1, P. Friend1, R. Hilton4, G. Lombardi5, K. Wood3

    1Kidney Transplantation, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, 2Kidney Transplantation, Guys and St Thomas's Hospital, London, United Kingdom, 3Transplant Immunology Research Group, Oxford University, Oxford, United Kingdom, 4Kidney Transplantation, Guys and St Thomas's Hospital, Oxford, United Kingdom, 5Transplant Immunology Group, Kings Healthcare Partners, London, United Kingdom

    *Purpose: A sequential clinical trial of autologous polyclonal T regulatory cellular therapy compared with a standardised reference cohort of live donor kidney transplant recipients. The…
  • 2020 American Transplant Congress

    Post- Transplant Recurrence of IgA Nephropathy: HLA as a Predictive Factor

    C. R. Kavanagh1, N. G. Jain1, R. Vasilescu2, J. Kamal3, I. Batal2

    1Pediatric Nephrology, Columbia University Medical Center, New York, NY, 2Pathology, Columbia University Medical Center, New York, NY, 3Surgery, Columbia University Medical Center, New York, NY

    *Purpose: Genomic studies have identified several HLA antigens to be associated with IgA Nephropathy in the native kidney. In contrast to the native kidney, there…
  • 2020 American Transplant Congress

    Clinical and Laboratory Characteristics of Early and Late-Onset Cytomegalovirus Infection Following Universal Prophylaxis in Kidney Transplant Recipients

    M. M. Tavakol, B. Lee, S. Ashimine, H. Crossman, M. Park, Z. Laszik, J. Roberts

    University of California, San Francisco, San Francisco, CA

    *Purpose: Cytomegalovirus (CMV) is the most important viral infection in organ recipients and can cause life-threatening infections, compromising long-term graft function. Most transplant centers use…
  • 2020 American Transplant Congress

    Impact of Focal Cortical Necrosis (CN) in Preimplantation Biopsy (PBx) on Outcomes after Deceased Donor Kidney Transplantation

    S. S. Nair, J. Ninan, R. Heilman, K. Reddy, M. Smith

    Mayo Clinic, Phoenix, AZ

    *Purpose: The data on outcomes of focal CN in PBx after deceased donor transplantation is sparse. We studied the prognostic value of focal CN on…
  • 2020 American Transplant Congress

    Empowering Patients to Self-Care Dialysis Previous to Kidney Transplantation Does Not Warrant Adherence to Immunosuppression

    F. Ortiz1, I. Helanterä2

    1Nephrology, Helsinki University Hospital, Helsinki, Finland, 2Kidney and Liver Transplantation, Helsinki University Hospital, Helsinki, Finland

    *Purpose: Nonadherence to immunosuppression increases the risk of kidney graft loss. We hypothesized that patient education to self-care dialysis has a positive impact on adherence…
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