Articles tagged "Graft survival"

2020 American Transplant Congress
Long Term Outcomes Following Uncontrolled and Controlled Donation after Cardiac Death Liver Transplantation in the United States
R. A. Choudhury¹, D. Yoeli¹, H. Yaffe¹, H. B. Moore¹, G. Hoeltzel², A. Schulick¹, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: Poor short-term outcomes following uncontrolled donation after cardiac death (uDCD) liver transplantation has led to near non-utilization of such donor allografts in the modern…
2020 American Transplant Congress
Autologous Expanded Tregs Promote Bone Marrow Engraftment and Donor Kidney Survival in Non-Human Primate Chimerism Model
K. Bruestle¹, P. Alonso-Guallart¹, H. Sakai¹, F. Fredriksson¹, B. Piegari¹, E. Lopes¹, G. Pierre¹, A. Shou¹, D. Ekanayake-Alper¹, J. Weiner¹, A. Iuga², S. M. Coley², M. Sykes¹, A. Griesemer¹
¹Columbia Center for Translational Immunology, Columbia University, New York City, NY, ²Department of Pathology and Cell Biology, Columbia University, New York City, NY
*Purpose: Mixed chimerism (MC) induced with non-myeloablative conditioning in monkeys and humans induces tolerance to 70% of kidney grafts transplanted at the time of BMT.…
2020 American Transplant Congress
Uncontrolled DCD vs DBD Liver Transplantation in the United States: Is it Safe to Push the Envelope?
R. A. Choudhury¹, D. Yoeli¹, H. Yaffe¹, H. B. Moore¹, G. Hoeltzel², A. Schulick¹, K. D. Conzen¹, J. J. Pomposelli¹, E. A. Pomfret¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA
*Purpose: Uncontrolled donation after cardiac death (uDCD) liver transplantation has been theorized as a potential option to increase the donor pool due to the typical…
2020 American Transplant Congress
Induction Therapy with Basiliximab versus Thymoglobulin in African-American Kidney Transplant Recipients in the Current Era of Immunosuppression
M. Zachariah¹, I. Mallawaarachchi², N. Meeks³, D. Wright¹, R. Minawala¹, V. Liu¹, J. Rolls⁴, S. Hussein⁴, C. Jarrin⁵
¹Wayne State University, Detroit, MI, ²Division of Biostatistics, University of Virginia, Charlottsville, VA, ³Wayne State University School of Medicine, Detroit, MI, ⁴Surgery, Detroit Medical Center, Detroit, MI, ⁵Infectious Disease, Wayne State University, Detroit, MI
*Purpose: It is now common practice in the transplant community to select induction therapy on the basis of perceived immunological risk for acute rejection which…
2020 American Transplant Congress
Managing the Road to Kidney Transplantation in the Elderly
R. S. Munjal, K. Kalra, A. Cherukuri, D. Jorgensen, S. Verma, P. Sood, R. Mehta, C. Puttarajappa, S. Hariharan, C. Wu
Nephrology, UPMC, Pittsburgh, PA
*Purpose: We hypothesize that careful patient selection and waitlist management minimizes the impact of advanced recipient age on kidney transplant outcomes.*Methods: A total of 3,521…
2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus: UNOS Data Set
H. Patel¹, K. Agrawal¹, A. Pawar¹, N. Leeaphorn², F. Cardarelli¹, N. Agrawal¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…
2020 American Transplant Congress
UNOS Hard to Place Kidneys: Are We Working Too Hard?
S. Chaudhry, K. L. King, S. A. Husain, D. Cohen, L. Ratner, S. Mohan
Columbia University, New York, NY
*Purpose: Kidneys requiring more than 100 offers before acceptance are defined by UNOS as “hard to place," but many are suitable for transplantation. We sought…
2020 American Transplant Congress
Improvement in Long Term Kidney Transplant Survival Most Dramatic among Minorities, Diabetics and Older Patients
E. D. Poggio¹, S. Arrigain², A. Wee³, D. C. Brennan⁴, J. D. Schold²
¹Nephrology, Cleveland Clinic, Cleveland, OH, ²Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, ³Urology, Cleveland Clinic, Cleveland, OH, ⁴Nephrology, Johns Hopkins, Baltimore, MD
*Purpose: Short-term and long-term kidney transplant graft survival has been improving over time, but whether this improvement in outcomes is more pronounced in the early…
2020 American Transplant Congress
Comparative Analysis of Risks Factors for Kidney Allograft Loss Due to Bk Nephropathy and Graft Loss Due to Other Causes: UNOS Data Set
H. Patel¹, L. Kruger¹, K. Agarwal¹, A. Pawar¹, N. Leeaphorn², F. Cardarelli¹, N. Agrawal¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO
*Purpose: 1-10% of the kidney transplant recipients develop BK virus nephropathy (BKVN). The risk factors associated with BKVN are not clearly understood. Here, we evaluate…
2020 American Transplant Congress
Outcomes Following Deceased Donor Split/Partial Liver Transplant for Hepatocellular Carcinoma
L. Matsuoka, T. Sutcliffe, I. Feurer, S. Rega, S. Alexopoulos
Vanderbilt University Medical Center, Nashville, TN
*Purpose: To mitigate waiting time for liver transplant for hepatocellular carcinoma (HCC) and increase available organs, partial or split liver transplant (SLT) has been utilized.…