Articles tagged "Graft survival"

2021 American Transplant Congress
Machine Learning Approaches for Post-transplant Kidney Outcome Prediction
H. Ghali¹, D. Won¹, S. Yoon¹, A. Friedman²
¹Systems Science and Industrial Engineering, SUNY Binghamton, Binghamton, NY, ²LiveOnNY, New York, NY
*Purpose: Determine a robust prediction model for kidney graft survival based on analyzing a combination of decisive factors such as donor and recipient characteristics, biopsy,…
2020 American Transplant Congress
Short Recipient Warm Ischemia Time Improves Graft Survival in Liver Transplantation from Donation after Brain Death: 20-Year Experience of Liver Transplantation
A. Al-Kurd, T. Kitajima, K. Delvecchio, A. M. Elsabbagh, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, S. Nagai
Transplant Institute, Henry Ford Hospital, Detroit, MI
*Purpose: Although the correlation between warm ischemia time (WIT) and the outcomes of liver transplantation has been extensively studied, few investigations have focused on the…
2020 American Transplant Congress
End-Hypothermic Oxygenated Machine Perfusion after Static Cold Storage versus Static Cold Storage Alone in Kidneys from Extended Criteria Brain-Dead Donors: An International Randomized Controlled Trial
P. Husen¹, C. Boffa², I. Jochmans³, C. Krikke⁴, L. Davies², H. Hofker⁴, J. Pirenne³, R. Ploeg², A. Paul¹
¹General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany, ²Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ³University Hospitals Leuven, Leuven, Belgium, ⁴University Medical Center Groningen, Groningen, Netherlands
*Purpose: A prospective, randomized, single-blinded, multicenter trial comparing the effect of short-term 'in house' oxygenated hypothermic machine preservation (End-HMPO2) following static cold storage (SCS) versus…
2020 American Transplant Congress
The Significance of Donor Gender on Graft Survival and Histological Ischemia Reperfusion Injury in Liver Transplant Patients
T. Ito, S. Kageyama, K. J. Dery, K. Nakamura, S. M. Younan, M. M. Lu, J. DiNorcia III, V. G. Agoian, H. Yersis, D. G. Farmer, R. W. Busuttil, F. M. Kaldas
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Experimental animal models have demonstrated improved ability of females (F) to recover from ischemia-reperfusion injury (IRI) compared with males (M). Recent work combining human…
2020 American Transplant Congress
NASH is the Leading Indication for Liver Transplantation in Elderly Patients
J. A. Steggerda¹, J. Yang², V. Sundaaram², N. Alkouri³, W. Ayoub², I. K. Kim¹, M. Noureddin²
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, ²Hepatology, Cedars-Sinai Medical Center, Los Angeles, Los Angeles, CA, ³Gastroenterology, University of Texas Health- San Antonio, San Antonio, TX
*Purpose: Non-alcoholic steatohepatitis (NASH) is an increasingly prevalent cause of end-stage liver disease (ESLD) and indication for liver transplantation (LT) in the United States and…
2020 American Transplant Congress
Impact of Severity of Glomerulosclerosis on Long-Term Outcomes in Deceased Donor Renal Transplant Recipients with Donor Acute Kidney Injury
A. Brar¹, A. Gruessner², D. Adey¹, M. Salifu²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: With long waitlist times for renal transplantation,there is a need to reduce discard rates of donor kidneys.The purpose of this study is to assess…
2020 American Transplant Congress
Comparative Analysis of Risk Factors and Outcomes in Kidney Transplant Recipients with Lung Cancer and Those with No Malignancy: UNOS Data Set
H. Patel¹, V. Nissaisorakarn², E. Sula Karrecci¹, N. Agrawal¹, F. Cardarelli¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Department of Internal Medicine, Metrowest Medical Center, Boston, MA
*Purpose: Transplant recipients are at increased risk for malignancy. Patients who develop cancer after transplant have worse outcomes, especially those with lung cancer. Transplant-related risk…
2020 American Transplant Congress
Severity of Donor Acute Kidney Injury Does Not Impact Long-Term Outcomes in Deceased Donor Renal Transplant Recipients
A. Brar¹, A. Gruessner², D. Adey¹, M. Salifu²
¹University of California, San Francisco, San Francisco, CA, ²SUNY Downstate Medical Center, Brooklyn, NY
*Purpose: Kidneys with increased donor terminal creatinine are frequently discarded. This study used national data to assess renal allograft and patient outcomes in deceased donor…
2020 American Transplant Congress
Graft Perfusion with an Hsp90 Inhibitor Prolongs Graft Survival in Murine Heart Transplantation by Modulating Expression of Cyclin-Dependent Kinases and the Senolytic Effect
T. Tanaka, T. Maehana, N. Masumori
Department of Urology, Sapporo Medical University, Sapporo, Japan
*Purpose: We have previously demonstrated that administration of alvespimycin, a heat shock protein 90 (HSP90) inhibitor, prolongs the allograft survival in murine skin and heart…
2020 American Transplant Congress
Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression
I. Booth¹, J. Casale¹, S. Freedman¹, B. Ravichandran¹, J. Scalea², A. Haririan², B. Masters¹
¹Pharmacy, University of Maryland Medical Center, Baltimore, MD, ²Medicine, University of Maryland Medical Center, Baltimore, MD
*Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…