2015 American Transplant Congress
Comparison of Clinical Outcomes Between in the Spousal Donor Kidney Tranplants: Wife-to-Husband Versus Husband-to-Wife
Backgrounds:There is few clinical outcome data between the wife-to-husband recipients(WTHr) and husband-to-wife recipients(HTWr) kidney transplantation. This study was conducted to compare the clinical outcomes between…2015 American Transplant Congress
Single Center Experience of C4d Staining of Kidney Transplant Biopsies
Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.
Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…2015 American Transplant Congress
Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of Graft Failure and Mortality Among Kidney Transplant Recipients
Purpose: Graft loss and death are generally late events after kidney transplantation, and trials designed to assess the impact of interventions on these outcomes are…2015 American Transplant Congress
The Spleen Is the Primary Site for Breg Induction and Is Required for Anti-TIM-1 Mediated Tolerance
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.
B cells can exhibit potent IL-10-dependent regulatory (Breg) activity. IL-10-enriched Bregs can transfer tolerance in auto and allo-immune models. We showed that TIM-1 is an…2015 American Transplant Congress
miRNA-181 Promotes Graft Prolongation by Plasmacytoid Dendritic Cells By Increasing T Regulatory Cells and Decreasing B Cells as Revealed By Cytometry By Time-Of-Flight
1Surgery, Stanford University, Stanford, CA; 2Pediatrics, UCSF, San Francisco, CA.
Liver allografts are well tolerated and other solid organ allografts, when transplanted concurrently with livers, show improved outcomes. However, the mechanisms underlying hepatic tolerance have…2015 American Transplant Congress
Retrospective Cohort Study Concerning Efficacy and Safety of Bortezomib in Combination With Or Without Rituximab in Antibody Mediated Rejection in Renal Transplant Recipients
Charité Universitätsmedizin Berlin, Department of Nephrology, Berlin, Germany.
Treatment of antibody-mediated rejection (AMR) in renal transplant (tx) patients (pts) is still challenging and long-term outcome remains unsatisfying. Because plasma cells (PCs) are crucial…2015 American Transplant Congress
Pancreatic Islet Survival Under Confinement
UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.
The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…2015 American Transplant Congress
Immunological Evaluation of Acellular Extracellular Matrix Upon Transplantation
Background : To mitigate the scanty supply of donor organs, porcine tissues can be utilized since, it embrace the potential to accomplish the task of…2015 American Transplant Congress
The Impact of Center Volume on Simultaneous Kidney-Pancreas Transplantation Outcomes
Background: Pancreas transplantation is associated with a high incidence of surgical complications and successful outcomes require experienced surgical and post-transplant care. Prior studies have linked…2015 American Transplant Congress
Intermittent High Dose Intravenous Immunoglobulin as Treatment for Donor Specific Antibodies in Renal Transplant Recipients
Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population have indicated…
