ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2015 American Transplant Congress

    Serum Creatinine Is Most Predictive of Graft Loss in Late Antibody Mediated Rejection

    G. Agarwal, D. Diskin, R. Reed, J. Locke, V. Kumar.

    Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham, AL.

    Development of acute antibody mediated rejection (AMR) is associated with graft loss and can occur both early (< 3 months) and late (> 3 months)…
  • 2015 American Transplant Congress

    A Preliminary Study of Using Small Intestinal Submucosa Scaffolds Coated Islets and Mesenchymal Stem Cells to Built Artificial Pancreas

    D. Wang, X. Ding, W. Xue, J. Zheng, X. Feng, X. Tian, Y. Li.

    Department of Renal Transplant, Center of Nephropathy, The First Affiliated Hospital, Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

    Background: Although islet transplantation successful applied, shortage of donors, poor islet survival and toxicity of immunosuppressants often reduce the graft functional lifetime. Tissue engineered scaffold…
  • 2015 American Transplant Congress

    Bladder Drainage of Pancreas Transplants Alone: Friend or Foe?

    M. Bellini,1 G. Spoletini,2 S. Reddy,1 J. Gilbert,1 I. Quiroga,1 R. Ploeg,1 E. Sharples,3 S. Sinha,1 A. Vaidya,1 P. Friend.1

    1Nuffield Department of Surgery, Oxford University Hospital NHS Trust, Oxford, United Kingdom; 2Department of Hepatobiliary and Transplant Surgery, Royal Free London NHS Trust, London, United Kingdom; 3Nuffield Department of Medicine, Oxford University Hospital NHS Trust, Oxford, United Kingdom.

    Introduction: Immunological monitoring of Pancreas Transplants Alone (PTA) remains a challenge and bladder drainage is thought to facilitate early detection of rejection but may lead…
  • 2015 American Transplant Congress

    Comparison of Clinical Outcomes Between in the Spousal Donor Kidney Tranplants: Wife-to-Husband Versus Husband-to-Wife

    K. Jun,1 H. Kim,1 M. Kim,1 K. Park,2 S. Ahn,1 J. Hwang,1 S. Kim,1 S. Park,1 S. Kim,1 J. Kim,1 I. Moon.1

    1Vascular and Transplant Surgery, The Catholic University of Korea, Seoul, Korea; 2Vascular Surgery, Inha University, Incheon, Korea.

    Backgrounds:There is few clinical outcome data between the wife-to-husband recipients(WTHr) and husband-to-wife recipients(HTWr) kidney transplantation. This study was conducted to compare the clinical outcomes between…
  • 2015 American Transplant Congress

    Single Center Experience of C4d Staining of Kidney Transplant Biopsies

    R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.

    Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
  • 2015 American Transplant Congress

    ABO-Incompatible Live Donor Kidney Transplants Inferior to ABO-Compatible Transplants, but Match Deceased Donor Results: Is Kidney Paired Donation the Answer?

    J. Verbesey, M. Cooper, A. Gilbert, M. Grafals, P. Weems, J. Moore, S. Ghasemian, C. Nilubol, B. Javaid.

    Georgetown University School of Medicine, MedStar Georgetown Transplant Institute, Kidney and Pancreas Transplant Program, Washington, DC.

    Objective: Compare kidney allograft survival in ABO-incompatible (ABO-I) and ABO-compatible (ABO-C) live donor kidney transplant recipients.Methods: We analyzed UNOS database for patients who underwent a…
  • 2015 American Transplant Congress

    Role of Innate Immune Cells in Chronic Allograft Loss and Novel Strategies to Target Them

    C. Wu,1,2 P. Zhao,1 W. Liu,1 X. Xiao,1 X. Shi,1 Y. Peng,1 M. Kloc,1 X. He,2 M. Ghobrial,1 X. Li.1

    1Center for Immunobiology and Transplantation Research, Houston Methodist Hospital and Houston Methodist Research Institute, Houston, TX; 2Organ Transplant Center, 1st Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.

    Despite remarkable improvements in short term transplant survival, the long-term outcome of allografts remains poor in the clinic, and most transplants are eventually lost due…
  • 2015 American Transplant Congress

    Kidney Plasmacytoid Dendritic Cells Display Distinct Cell Surface Markers and May Explain the Induction of Tolerance by Kidney Allografts

    N. Oh, M. Tonsho, D. Ndishabandi, R. Colvin, J. Madsen, A. Alessandrini.

    Massachusetts General Hospital, Boston, MA.

    Achieving tolerance in heart allografts is an important area of research as the need for heart transplantations increase. Recent studies in non-human primates (NHPs) have…
  • 2015 American Transplant Congress

    Retrospective Cohort Study Concerning Efficacy and Safety of Bortezomib in Combination With Or Without Rituximab in Antibody Mediated Rejection in Renal Transplant Recipients

    M. Duerr, N. Lachmann, K. Budde, J. Waiser.

    Charité Universitätsmedizin Berlin, Department of Nephrology, Berlin, Germany.

    Treatment of antibody-mediated rejection (AMR) in renal transplant (tx) patients (pts) is still challenging and long-term outcome remains unsatisfying. Because plasma cells (PCs) are crucial…
  • 2015 American Transplant Congress

    Pancreatic Islet Survival Under Confinement

    A. Rodriguez, S. Sigrist, E. Maillard.

    UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.

    The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
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