ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Graft survival"

  • 2015 American Transplant Congress

    Comparison of Clinical Outcomes Between in the Spousal Donor Kidney Tranplants: Wife-to-Husband Versus Husband-to-Wife

    K. Jun,1 H. Kim,1 M. Kim,1 K. Park,2 S. Ahn,1 J. Hwang,1 S. Kim,1 S. Park,1 S. Kim,1 J. Kim,1 I. Moon.1

    1Vascular and Transplant Surgery, The Catholic University of Korea, Seoul, Korea; 2Vascular Surgery, Inha University, Incheon, Korea.

    Backgrounds:There is few clinical outcome data between the wife-to-husband recipients(WTHr) and husband-to-wife recipients(HTWr) kidney transplantation. This study was conducted to compare the clinical outcomes between…
  • 2015 American Transplant Congress

    Single Center Experience of C4d Staining of Kidney Transplant Biopsies

    R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.

    Division of Nephrology and Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While a diffuse positivity (>50%) of C4d in kidney transplant peritubular capillaries strongly co-relates with the presence of acute or chronic antibody mediated rejection,…
  • 2015 American Transplant Congress

    Decline in Estimated Glomerular Filtration Rate and Subsequent Risk of Graft Failure and Mortality Among Kidney Transplant Recipients

    P. Clayton,1,2,3 W. Lim,1,4 S. Chadban.1,2,3

    1Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, Australia; 2Transplantation, Royal Prince Alfred Hospital, Sydney, Australia; 3Sydney Medical School, University of Sydney, Sydney, Australia; 4Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia.

    Purpose: Graft loss and death are generally late events after kidney transplantation, and trials designed to assess the impact of interventions on these outcomes are…
  • 2015 American Transplant Congress

    The Spleen Is the Primary Site for Breg Induction and Is Required for Anti-TIM-1 Mediated Tolerance

    K. Mohib, Q. Ding, A. Cherukuri, D. Rothstein.

    Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA.

    B cells can exhibit potent IL-10-dependent regulatory (Breg) activity. IL-10-enriched Bregs can transfer tolerance in auto and allo-immune models. We showed that TIM-1 is an…
  • 2015 American Transplant Congress

    miRNA-181 Promotes Graft Prolongation by Plasmacytoid Dendritic Cells By Increasing T Regulatory Cells and Decreasing B Cells as Revealed By Cytometry By Time-Of-Flight

    A. Lau,1,2 M. Vitalone,1 X. Qu,1 T. Shawler,1 O. Martinez,1 C. Esquivel,1 S. Krams.1

    1Surgery, Stanford University, Stanford, CA; 2Pediatrics, UCSF, San Francisco, CA.

    Liver allografts are well tolerated and other solid organ allografts, when transplanted concurrently with livers, show improved outcomes. However, the mechanisms underlying “hepatic tolerance” have…
  • 2015 American Transplant Congress

    Retrospective Cohort Study Concerning Efficacy and Safety of Bortezomib in Combination With Or Without Rituximab in Antibody Mediated Rejection in Renal Transplant Recipients

    M. Duerr, N. Lachmann, K. Budde, J. Waiser.

    Charité Universitätsmedizin Berlin, Department of Nephrology, Berlin, Germany.

    Treatment of antibody-mediated rejection (AMR) in renal transplant (tx) patients (pts) is still challenging and long-term outcome remains unsatisfying. Because plasma cells (PCs) are crucial…
  • 2015 American Transplant Congress

    Pancreatic Islet Survival Under Confinement

    A. Rodriguez, S. Sigrist, E. Maillard.

    UMR DIATHEC EA 7294, Centre Européen d'Etude du Diabète, Strasbourg, France.

    The main advantage of cell therapy is the possibility to immune-isolate the graft in a device to avoid immune suppressive regimen. In islet transplantation field,…
  • 2015 American Transplant Congress

    Immunological Evaluation of Acellular Extracellular Matrix Upon Transplantation

    M. Ketaki,1 P. Pradeep,1 N. Nikhil,1 G. Dellgren,3 H. Suchitra, M. Olausson.2

    1Laboratory for Transplantation Regenerative Medicine, Surgery, Gothenburg University, Gothenburg, Sweden; 2Department of Surgery, SU/Sahlgrenska University Hospital, SE 41345, Gothenburg, Sweden; 3Cardiothoracic Surgery, Transplant Institute, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.

    Background : To mitigate the scanty supply of donor organs, porcine tissues can be utilized since, it embrace the potential to accomplish the task of…
  • 2015 American Transplant Congress

    The Impact of Center Volume on Simultaneous Kidney-Pancreas Transplantation Outcomes

    A. Malone,1 D. Brennan,1 J. Wellen,2 T. Alhamad.1

    1Transplantation Nephrology, Renal Division, Washington University, St Louis; 2Section of Transplant Surgery, Washington University, St Louis.

    Background: Pancreas transplantation is associated with a high incidence of surgical complications and successful outcomes require experienced surgical and post-transplant care. Prior studies have linked…
  • 2015 American Transplant Congress

    Intermittent High Dose Intravenous Immunoglobulin as Treatment for Donor Specific Antibodies in Renal Transplant Recipients

    P. Bolin,1 K. Parker,2 F. Rana,1 W. Bryant,1 P. Jawa,1 R. Harland.3

    1Internal Medicine, East Carolina University, Brody School of Medicine, Greenville, NC; 2Vidant Medical Center, Greenville, NC; 3Surgical Immunology and Transplantation, East Carolina University, Brody School of Medicine, Greenville, NC.

    Background: Donor-specific HLA antibody (DSA) formation in post-renal transplant patients is associated with chronic rejection and graft failure. Previous studies in our population have indicated…
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