2015 American Transplant Congress
Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection
Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…2015 American Transplant Congress
Three Year Outcomes of Renal Allograft Transplants in African American Recipients Receiving Alemtuzumab for Induction Immunosuppression
Ochsner Clinic Foundation, New Orleans, LA.
Background:Induction with Alemtuzumab is well documented to reduce the incidence and severity of acute rejection episodes, which may improve graft survival. Limited data are available…2015 American Transplant Congress
Immunologic Long-Term Outcome of Living Kidney Transplantation Depending On the Donor-Recipient Relationship
Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany.
Background. Only few data is available about long-term immunologic outcomes of living kidney transplantation (KTx) depending on the donor-recepient relationship.Patients and methods. This single center…2015 American Transplant Congress
Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation
Transplant Institute, Georgetown University Hospital, Washington, DC.
IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…2015 American Transplant Congress
Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2)
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…2015 American Transplant Congress
Is There a Difference in Patient and Graft Survival in Children Weighing <20 kg Versus Those Weighing >20 kg at the Time of Renal Transplantation?
Introduction: Renal transplantation (RTx) is the gold standard treatment modality for end-stage kidney disease. There are increased challenges in pediatric renal transplant recipients (pRTR) under…2015 American Transplant Congress
Targeting Complement Pathways During Ischemia and Reperfusion: Implications for the Prevention of Delayed Graft Function
Complement system plays a critical role in ischemia-reperfusion injury (IRI), and contributes to DGF. The aim of this study was to evaluate the effects of…2015 American Transplant Congress
Pancreas-Derived Mesenchymal Stem Cells from Chronic Pancreatitis Patients Enhance Islet Graft Function
PURPOSE: Islet transplantation represents a promising procedure to reverse or prevent diabetes. However, significant mass of islet graft is lost within hours of transplantation due…2015 American Transplant Congress
Complement Inhibition Via the Lectin Pathway Improves Experimental Cardiac Graft Survival
Purpose: While complement activation via both the classical as well as the lectin pathway is believed to contribute to allograft loss, their relative contribution is…2015 American Transplant Congress
A Novel Maintenance Regimen With Calcineurin Inhibitor, MMF and Everolimus Initiated By Dual Induction Therapy With Anti-CD20/25 Antibodies in Renal Transplantation
Surgery III, Tokyo Women's Medical University Hospital, Shinjuku-ku,Tokyo, Japan.
【background】Calcineurin inhibitor (CNI), MMF and steroid has been the gold standard of maintenance regimen in renal transplantation (RTx). A line of new immunosuppressants has emerged…