Articles tagged "Graft survival"

2015 American Transplant Congress
Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients
J. Locke,¹ R. Reed,¹ S. Mehta,¹ C. Durand,² R. Mannon,¹ P. MacLennan,¹ B. Shelton,¹ M. Martin,¹ H. Qu,¹ R. Shewchuk,¹ D. Segev.²
¹Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham; ²Comprehensive Transplant Center, Johns Hopkins Medical Institutions, Baltimore.
Background: Excellent outcomes among HIV+ kidney transplant (KT) recipients have been reported by the NIH consortium, but it is unclear if experience with HIV+ KT…
2015 American Transplant Congress
Immunological Aspects of Iron Overload in Heart and Kidney Transplantation
T. Resch,¹ S. Ebner,¹ P. Ritschl,¹ M. Ashraf,¹ C. Fabritius,¹ A. Brunner,² V. Nguyen,¹ J. Günther,¹ J. Pratschke,³ K. Kotsch.¹
¹Department of Surgery, Medical University Innsbruck, Innsbruck, Austria; ²Department of Pathology, Medical University Innsbruck, Innsbruck, Austria; ³Department of Surgery, Charité, Berlin, Germany.
Background: Clinical data suggest that iron (Fe) overload deleteriously affects graft survival after heart (HTX) and kidney transplantation (KTX) but possible immunologic mechanisms underlying this…
2015 American Transplant Congress
Poor Renal Function and Increased Mortality in Elderly Recipients of Deceased Donor Kidneys from Elderly Donors
S. Berger,¹ H. Peters-Sengers,² M. Heemskerk,³ F. Bemelman,² J. Homan van der Heide.²
¹Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands; ²Department of Nephrology, Academic Medical Center, Amsterdam, Netherlands; ³Dutch Transplant Foundation, Leiden, Netherlands.
Background: Within the Eurotransplant Senior Program kidneys form donors older than 65 both after cardiac death (DCD) or brain death (DBD) are allocated to recipients…
2015 American Transplant Congress
Kidney Transplant Outcomes in Patients With Amyloidosis
J. Verbesey, M. Cooper, P. Weems, A. Gilbert, M. Grafals, C. Nilubol, J. Moore, S. Ghasemian, B. Javaid.
Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC.
Objective: Analyze kidney allograft outcomes in patients with kidney failure due to amyloidosis, and compare kidney transplant survival to patients with other causes of kidney…
2015 American Transplant Congress
Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients
H. Monsour Jr,¹ M. Boktour,² A. Abimbola,¹ M. Elnemr,¹ S. Gordon Burroughs,² D. Victor III,¹ A. Saharia,² B. Trachtenberg,³ A. Bhimaraj,³ A. Gaber,² J. Estep,³ R. Ghobrial.²
¹Department of Medicine, Houston Methodist Hospital, Houston, TX; ²Department of Surgery, Houston Methodist Hospital, Houston, TX; ³Cardiology Department, Houston Methodist Hospital, Houston, TX.
Background: Combined heart-liver transplantation (CHLT) is life-saving for patients with end-stage heart-liver diseases. This is a review of patients who underwent CHLT at a single-center.Methods:…
2015 American Transplant Congress
Anti-BTLA Antibody (6B2) Induced Prolongation of Fully MHC-Mismatched Murine Cardiac Allograft and Generation of Foxp3+ Regulatory T Cells
M. Uchiyama,^1,2,3 E. Yin,^3,4 X. Jin,^3,5 T. Shimokawa,¹ H. Yagita,² M. Niimi.³
¹Cardiovascular Surgery, Teikyo University, Tokyo, Japan; ²Immunology, Juntendo University Hospital, Tokyo, Japan; ³Surgery, Teikyo University, Tokyo, Japan; ⁴Cardiovascular Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China; ⁵Cardiovascular and Thoracic Surgery, The 4th Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…
2015 American Transplant Congress
Outcomes of Patients With Hepatocellular Carcinoma Receiving a Donation After Cardiac Death Liver Graft
W. Goldkamp,¹ J. Vanatta,^2,3 S. Nair,^2,3 E. Wong,³ N. Dbouk.^2,3
¹Internal Medicine, The Universty of Tennessee Health Science Center, Memphis, TN; ²Surgery, The Universty of Tennessee Health Science Center, Memphis, TN; ³Methodist Universty Hospital Transplant Institute, Memphis, TN.
Background: Recent data suggests that patients with Hepatocellular carcinoma (HCC) who receive a donation after cardiac death (DCD) graft have inferior graft and patient survival…
2015 American Transplant Congress
The Gut Microbiota Regulates Murine Cardiac Transplant Outcome
C. Brinkman,¹ L. Hittle,¹ E. Mongodin,¹ W. Fricke,² J. Bromberg.¹
¹University of Maryland, Baltimore, MD; ²University of Hohenheim, Stuttgart, Germany.
Hypothesis: The gut microbiota regulates systemic immunity. Different characteristics of the microbiota can be defined that have pro- or anti-inflammatory effects. We tested the hypothesis…
2015 American Transplant Congress
Neighborhood Poverty Modifies Gender Disparities in Kidney Transplant Outcomes
T. Purnell, X. Luo, A. Massie, D. Crews, L. Cooper, D. Segev.
Johns Hopkins, Baltimore.
Earlier studies report mixed findings comparing transplant outcomes in women versus men, and little is known about the association of socioeconomic status (SES) with gender…
2015 American Transplant Congress
Depression of Complement Regulatory Factors in Human and Rat Renal Grafts in Association With Progress of Acute Cellular Rejection
K. Yamanaka,^１ T. Kato,^１ Y. Kakuta,¹ T. Abe,¹ R. Imamura,¹ A. Maeda,² S. Miyagawa,² N. Nonomura.¹
¹Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; ²Organ Transplantation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Introduction and ObjectiveIt is commonly known that complements play important roles in antibody mediated rejection in renal transplantation. However, the association of complements with progression…