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Articles tagged "Graft survival"

  • 2015 American Transplant Congress

    Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients

    H. Monsour Jr,1 M. Boktour,2 A. Abimbola,1 M. Elnemr,1 S. Gordon Burroughs,2 D. Victor III,1 A. Saharia,2 B. Trachtenberg,3 A. Bhimaraj,3 A. Gaber,2 J. Estep,3 R. Ghobrial.2

    1Department of Medicine, Houston Methodist Hospital, Houston, TX; 2Department of Surgery, Houston Methodist Hospital, Houston, TX; 3Cardiology Department, Houston Methodist Hospital, Houston, TX.

    Background: Combined heart-liver transplantation (CHLT) is life-saving for patients with end-stage heart-liver diseases. This is a review of patients who underwent CHLT at a single-center.Methods:…
  • 2015 American Transplant Congress

    Anti-BTLA Antibody (6B2) Induced Prolongation of Fully MHC-Mismatched Murine Cardiac Allograft and Generation of Foxp3+ Regulatory T Cells

    M. Uchiyama,1,2,3 E. Yin,3,4 X. Jin,3,5 T. Shimokawa,1 H. Yagita,2 M. Niimi.3

    1Cardiovascular Surgery, Teikyo University, Tokyo, Japan; 2Immunology, Juntendo University Hospital, Tokyo, Japan; 3Surgery, Teikyo University, Tokyo, Japan; 4Cardiovascular Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China; 5Cardiovascular and Thoracic Surgery, The 4th Affiliated Hospital of Harbin Medical University, Harbin, China.

    Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA; CD272) has been implicated in the regulation of autoimmune and may potentially play an important…
  • 2015 American Transplant Congress

    Outcomes of Patients With Hepatocellular Carcinoma Receiving a Donation After Cardiac Death Liver Graft

    W. Goldkamp,1 J. Vanatta,2,3 S. Nair,2,3 E. Wong,3 N. Dbouk.2,3

    1Internal Medicine, The Universty of Tennessee Health Science Center, Memphis, TN; 2Surgery, The Universty of Tennessee Health Science Center, Memphis, TN; 3Methodist Universty Hospital Transplant Institute, Memphis, TN.

    Background: Recent data suggests that patients with Hepatocellular carcinoma (HCC) who receive a donation after cardiac death (DCD) graft have inferior graft and patient survival…
  • 2015 American Transplant Congress

    Outcomes of ABO Incompatible Kidney Transplantation in Children

    J. Stojanovic,1 A. Adamusiak,2 A. Waters,1 D. Bockenhauer,1 N. Kessaris,2 C. Barton,3 H. Jones,3 J. Taylor,3 S. Marks,1 N. Mamode.2

    1Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom; 2Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; 3Department of Paediatric Nephrology, Evelina London Children's Hospital, London, United Kingdom.

    Purpose: ABO blood group incompatible transplantation (ABOi) has become increasingly common over the last decade, in part due to a shortage of suitable deceased donor…
  • 2015 American Transplant Congress

    Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients

    J. Locke,1 R. Reed,1 S. Mehta,1 C. Durand,2 R. Mannon,1 P. MacLennan,1 B. Shelton,1 M. Martin,1 H. Qu,1 R. Shewchuk,1 D. Segev.2

    1Comprehensive Transplant Institute, University of Alabama at Birmingham, Birmingham; 2Comprehensive Transplant Center, Johns Hopkins Medical Institutions, Baltimore.

    Background: Excellent outcomes among HIV+ kidney transplant (KT) recipients have been reported by the NIH consortium, but it is unclear if experience with HIV+ KT…
  • 2015 American Transplant Congress

    Immunological Aspects of Iron Overload in Heart and Kidney Transplantation

    T. Resch,1 S. Ebner,1 P. Ritschl,1 M. Ashraf,1 C. Fabritius,1 A. Brunner,2 V. Nguyen,1 J. Günther,1 J. Pratschke,3 K. Kotsch.1

    1Department of Surgery, Medical University Innsbruck, Innsbruck, Austria; 2Department of Pathology, Medical University Innsbruck, Innsbruck, Austria; 3Department of Surgery, Charité, Berlin, Germany.

    Background: Clinical data suggest that iron (Fe) overload deleteriously affects graft survival after heart (HTX) and kidney transplantation (KTX) but possible immunologic mechanisms underlying this…
  • 2015 American Transplant Congress

    Poor Renal Function and Increased Mortality in Elderly Recipients of Deceased Donor Kidneys from Elderly Donors

    S. Berger,1 H. Peters-Sengers,2 M. Heemskerk,3 F. Bemelman,2 J. Homan van der Heide.2

    1Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands; 2Department of Nephrology, Academic Medical Center, Amsterdam, Netherlands; 3Dutch Transplant Foundation, Leiden, Netherlands.

    Background: Within the Eurotransplant Senior Program kidneys form donors older than 65 both after cardiac death (DCD) or brain death (DBD) are allocated to recipients…
  • 2015 American Transplant Congress

    Immunologic Long-Term Outcome of Living Kidney Transplantation Depending On the Donor-Recipient Relationship

    D. Khadzhynov, F. Halleck, D. Schmidt, S. Kreimer, K. Budde, O. Staeck.

    Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany.

    Background. Only few data is available about long-term immunologic outcomes of living kidney transplantation (KTx) depending on the donor-recepient relationship.Patients and methods. This single center…
  • 2015 American Transplant Congress

    Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation

    M. Ertreo, C. Desai, R. Girlanda, T. Frias, T. Fishbein.

    Transplant Institute, Georgetown University Hospital, Washington, DC.

    IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…
  • 2015 American Transplant Congress

    Indefinite Survival of Fully MHC-Mismatched Murine Cardiac Allografts by Combination of Anti-BTLA mAb (6B2) and Anti-PD-1 mAb (PIM-2)

    E. Yin,1,2 M. Uchiyama,1,3,4 X. Jin,1,5 T. Shimokawa,3 H. Yagita,4 M. Niimi.1

    1Department of Surgery, Teikyo University, Tokyo, Japan; 2Department of Cardiovascular Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China; 3Department of Cardiovascular Surgery, Teikyo University, Tokyo, Japan; 4Department of Immunology, Juntendo University Hospital, Tokyo, Japan; 5Department of Cardiovascular and Thoracic Surgery, The 4th Affiliated Hospital of Harbin Medical University, Harbin, China.

    Background: The co-inhibitory receptor B and T lymphocyte attenuator (BTLA) and Programmed death (PD)-1 had been suggested to have immunomodulatory activity. This study investigated the…
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