Articles tagged "Graft survival"

2022 American Transplant Congress
Complete and High-Resolution HLA Typing Improves the Accuracy of Post-Transplant Assessment of De Novo Anti-Donor Immune-Mediated Events
M. Meneghini¹, A. Perona², E. Crespo³, F. J. Bemelman⁴, P. M. Reinke⁵, O. Viklicky⁶, M. Giral⁷, O. Bestard¹
¹Vall d'Hebron University Hospital, Barcelona, Spain, ²Universitat de Barcelona, Barcelona, Spain, ³Nephrology and Transplantation Laboratory, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, ⁴Amsterdam University Medical Centers, Amsterdam, Netherlands, ⁵Charité Universitätsmedizin, Berlin, Germany, ⁶Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, ⁷Nantes Université, Inserm, CHU Nantes, Nantes, France
*Purpose: High-resolution (HR) HLA typing using NGS technology has shown to improve the accuracy of assessing donor-recipient compatibility and characterization of pre-transplant anti HLA antibodies…
2022 American Transplant Congress
Kinetic Analysis of Post-Clearance Phase Inflammation in Kidney Biopsies After BK Viremia
M. Vincent¹, J. T. Rajagopal¹, E. Farkash²
¹University of Michigan, Ann Arbor, MI, ²Dept. of Pathology, University of Michigan, Ann Arbor, MI
*Purpose: During the post-clearance phase of BK polyomavirus nephropathy, tubulointerstitial inflammation can persist despite resolution of BK viremia. This inflammation is indistinguishable from low grade…
2022 American Transplant Congress
High Level Cytomegalovirus Viremia in Liver Transplant Recipients: Risk Factors and Associated Outcomes
H. L. Kleiboeker¹, M. R. Jorgenson¹, G. E. Leverson², J. P. Rice³, C. M. Saddler⁴, J. A. Smith⁴, D. Al-Adra³
¹Pharmacy, University of Wisconsin Hospital and Clinics, Madison, WI, ²Department of Surgery, UW School of Medicine and Public Health, Madison, WI, ³Department of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ⁴Department of Medicine, Division of Infectious Diseases, University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: To evaluate epidemiology, risk-factors and outcomes of high-level CMV viremia in LTX recipients.*Methods: Retrospective review of adults who received LTX between 1/1/2017-9/30/2020. Inclusion criteria…
2022 American Transplant Congress
Validation of the iBox Surrogate End Point in CNI Free, Belatacept Treated Patients (BENEFIT & BENEFIT-EXT)
G. Divard¹, O. Aubert¹, M. Raynaud¹, F. Vincenti², L. Rostaing³, A. Durbach⁴, C. Legendre¹, R. Vadanici⁵, A. Loupy¹, -. BENEFIT & BENEFIT-EXT Investigators⁶
¹Paris Transplant Group, INSERM, Paris, France, ²UCSF, San Francisco, CA, ³Grenoble, Grenoble, France, ⁴APHP, Paris, France, ⁵BMS, Rueil Malmaison, France, ⁶BMS, New York, NY
*Purpose: The iBox is a prognostication system for long-term kidney allograft survival, developed with mostly patients under a CNI based immunosuppression. Patients treated with a…
2022 American Transplant Congress
Bone Effect and Safety of One Year Denosumab Therapy in a Cohort of Renal Transplanted Patients: An Observational Monocentric Study
C. Alfieri, M. Gandolfo, D. Cresseri, M. Campise, A. Regalia, P. Messa, G. Castellano
Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico Milano, Milano, Italy
*Purpose: In our observational monocentric study, we evaluated the effects on femoral and lumbar bone mineral density (BMD) and on MM parameters, and the safety…
2022 American Transplant Congress
COVID-19 Infection Post-Transplant: What is the Collateral Damage to the Graft? A Case for Pre-Transplant Vaccination
A. Fabick¹, E. Overly¹, V. Rao², V. Rohan³, N. Patel¹, D. DuBay³, C. Candland³, N. Pilch¹
¹Department of Pharmacy, Medical University of South Carolina, Charleston, SC, ²Department of Transplant Nephrology, Medical University of South Carolina, Charleston, SC, ³Department of Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: COVID-19 produces an unpredictable immune reaction and is challenging to manage during active infection and post-infection, in kidney transplant (KTX) recipients. The first peak…
2022 American Transplant Congress
Long Term Analysis of Pediatric En-Bloc Kidney Transplantation: A Single Center Experience
H. H. Patel¹, P. Di Cocco², J. Almario², A. Fratti², S. Akshelyan², E. Benedetti², I. Tzvetanov², M. Spaggiari²
¹University of Missouri-Kansas City School of Medicine, Kansas City, MO, ²University of Illinois at Chicago, Chicago, IL
*Purpose: Pediatric en-bloc kidney transplantations for adult recipients are uncommonly performed due to unique donor characteristics, the technical challenge of the operation, and potential surgical…
2022 American Transplant Congress
Outcome of Living Donor Kidney Transplant and Deceased Donor Kidney Transplant: A Retrospective Cohort Study at National Kidney and Transplant Institute
A. B. Burog, A. Parayno
ORGAN TRANSPLANTATION AND VASCULAR SURGERY, National Kidney And Transplant Institute, Quezon City, Philippines
*Purpose: To compare the graft and patient survival of living and deceased donor kidney transplant and identify the factors that affect graft survival.*Methods: Retrospective cohort…
2022 American Transplant Congress
Binding Mechanisms For Donor Dc-derived Exosomes To Cross-dress Of Recipient Dc
L. ZHANG¹, X. LI¹, J. LIU¹, H. WEI¹, C. LI¹, A. HUANG², C. ZHENG¹, Q. LIU¹
¹Department of Biochemistry, Southern University of Science and Technology, Shenzhen, China, ²Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Our previous evidence suggests donor dendritic cell (DC)-derived exosomes cross-dress recipient DC after heart transplantation in mice. This process plays a critical role in…
2022 American Transplant Congress
Risk Factors Associated with Medium-Term Allograft and Recipient Survival: Learned from 1,587 Adults with Single Kidney Transplantation
S. Chang¹, B. Liu¹, D. Du¹, N. Gong², L. Zhu¹, G. Chen¹, W. Zhang¹, Z. Chen²
¹Institute of Organ Transplantation,Tongji Hospital,Tongji Medical College,HUST, Wuhan, China, ²Huazhong University of Science and Technology, Wuhan, China
*Purpose: Retrospectively investigated the reason for graft failure during the perioperative period and discussed whether DGF and the high SCr level in a short time…